Benzodiazepines Overview Quiz

<p>Buspirone. (B)</p> Signup and view all the answers

<p>Hypnotics induce sleep, while anxiolytics reduce anxiety, although some overlap exists. (B)</p> Signup and view all the answers

<p>Modafinil. (B)</p> Signup and view all the answers

<p>Anterograde amnesia. (C)</p> Signup and view all the answers

<p>They are rapidly metabolized by the liver. (C)</p> Signup and view all the answers

<p>Drowsiness (C)</p> Signup and view all the answers

<p>Seizures (C)</p> Signup and view all the answers

<p>Chloral hydrate (C)</p> Signup and view all the answers

<p>Benzodiazepines (A)</p> Signup and view all the answers

<p>Flushing and nausea (B)</p> Signup and view all the answers

<p>Has a shallow dose-response curve (A)</p> Signup and view all the answers

<p>Milder withdrawal symptoms (B)</p> Signup and view all the answers

<p>Constipation (B)</p> Signup and view all the answers

<p>Alprazolam (A)</p> Signup and view all the answers

<p>They are highly addictive and can lead to dependence. (B)</p> Signup and view all the answers

<p>They have a long half-life, potentially leading to daytime sedation and accumulation. (D)</p> Signup and view all the answers

<p>Drowsiness and confusion (C)</p> Signup and view all the answers

<p>Activation of specific GABA receptors in the brain (D)</p> Signup and view all the answers

<p>It is a benzodiazepine receptor antagonist with a short half-life, used to treat overdose. (B)</p> Signup and view all the answers

<p>They have a high therapeutic index and a wide safety margin. (C)</p> Signup and view all the answers

<p>They can cross the placenta and depress the newborn's respiratory system. (C)</p> Signup and view all the answers

<p>Their metabolism and clearance are slower, leading to potential accumulation. (D)</p> Signup and view all the answers

<p>Tolerance develops primarily to the sedative-hypnotic and anticonvulsant effects, but not to anxiolytic effects. (A)</p> Signup and view all the answers

<p>Seizures and death (A)</p> Signup and view all the answers

<p>They are highly protein-bound, but few clinically significant drug interactions occur. (C)</p> Signup and view all the answers

<p>Zolpidem (B)</p> Signup and view all the answers

<p>Zaleplon (B)</p> Signup and view all the answers

<p>Benzodiazepines (C)</p> Signup and view all the answers

<p>Buspirone (D)</p> Signup and view all the answers

<p>Hydroxyzine (C)</p> Signup and view all the answers

<p>Flumazenil (C)</p> Signup and view all the answers

<p>Benzodiazepines (C)</p> Signup and view all the answers

<p>Clonidine (D)</p> Signup and view all the answers

<p>Propranolol (C)</p> Signup and view all the answers

<p>Thiopental (C)</p> Signup and view all the answers

<p>Barbiturates can block excitatory glutamate receptors. (B)</p> Signup and view all the answers

<p>Phenobarbital (D)</p> Signup and view all the answers

<p>Barbiturates may potentiate the effects of other central nervous system (CNS) depressants. (D)</p> Signup and view all the answers

<p>Benzodiazepines should be used cautiously in patients with liver disease. (D)</p> Signup and view all the answers

<p>Barbiturates have a high potential for dependence and severe withdrawal symptoms. (B)</p> Signup and view all the answers

Medications used to reduce anxiety symptoms.

A class of drugs used primarily as anxiolytics and hypnotics; examples include Diazepam and Alprazolam.

Benzodiazepines enhance GABA effects by binding to specific sites on its receptors, increasing channel openings.

A potential side effect of benzodiazepines, leading to an inability to form new memories after taking the drug.

Medications aimed at inducing sleep, which may also have anxiolytic effects.

A phenomenon where the effectiveness of a drug decreases over time with continuous use, often occurring in 1-2 weeks.

An anxiolytic drug that works differently than benzodiazepines and does not cause sedation.

An antagonist of benzodiazepines used to reverse their effects, particularly in overdose situations.

The study of drug movement through the body.

Symptoms include drowsiness and impaired concentration, especially with barbiturates.

Abrupt withdrawal from certain drugs can cause severe symptoms.

Can lead to respiratory depression and is often fatal.

Blocks acetaldehyde oxidation, causing severe reactions to alcohol.

Metabolized to acetaldehyde and then acetate primarily in the liver.

An effective sedative that induces sleep within 30 minutes.

Diphenhydramine and doxylamine are used to treat mild insomnia.

Conditions characterized by excessive fear or worry, treated by benzodiazepines.

A benzodiazepine effective for panic disorders, short and long-term.

A benzodiazepine used for the chronic treatment of epilepsy.

A long-acting benzodiazepine for anxiety and muscle spasms.

Short-acting benzodiazepines used for memory loss during procedures.

A long-acting benzodiazepine for insomnia, effective up to 4 weeks.

Symptoms experienced during discontinuation of benzodiazepines, such as anxiety.

Calming effects produced by some benzodiazepines.

Tolerance that occurs with related substances, like alcohol and benzodiazepines.

Undesired side effects from benzodiazepines like drowsiness and confusion.

Benzodiazepines that are effective for insomnia and sleep disorders.

Benzodiazepines can have additive effects when used with other central nervous system depressants like alcohol.

A hypnotic agent acting on BZ1 receptors, used for insomnia with minimal tolerance effects.

An oral sedative for insomnia, known for a half-life of 6 hours and side effects like dry mouth.

An antihistamine with sedative properties used for anxiety and pre-surgery sedation.

An alpha-2 agonist used for anxiety, especially during nicotine or opioid withdrawal.

A beta-blocker used for anxiety symptoms like trembling and palpitations, especially in performance anxiety.

Sedatives that have largely been replaced by benzodiazepines due to dependence risks and severe withdrawal.

A long-acting barbiturate used to treat seizures.

An ultra-short-acting barbiturate used for IV anesthetic induction.

Receptors that benzodiazepines and barbiturates enhance to produce their sedative effects.