Dementia
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Questions and Answers

Which of the following is a motor feature commonly seen in patients exhibiting Parkinsonian movements?

  • Enhanced cognitive abilities
  • Rigidity (correct)
  • Increased energy levels
  • Rapid speech

What type of neurodegeneration is primarily associated with Behavioural-Variant Frontotemporal Dementia?

  • Accumulation of abnormal tau protein (correct)
  • Insulin resistance in the brain
  • Decrease in amyloid plaques
  • Neurofibrillary tangles in occipital lobe

Which symptom is NOT commonly associated with Behavioural-Variant Frontotemporal Dementia?

  • Memory deficits (correct)
  • Preference for sweets
  • Repetitive behaviors
  • Lack of insight

Which behavioral symptom may be present in patients with Behavioural-Variant Frontotemporal Dementia?

<p>Emotional rigidity (A)</p> Signup and view all the answers

What characterizes mild cognitive impairment?

<p>Some deficits upon testing but not severe enough to cause problems in day-to-day living (D)</p> Signup and view all the answers

Which cognitive abilities are likely to show declines in life-long processing speed?

<p>Working memory (C)</p> Signup and view all the answers

What does subjective cognitive decline refer to?

<p>An experience of cognitive decline without objective impairment (A)</p> Signup and view all the answers

At what age do thinking skills typically peak, according to normal age-related cognitive decline?

<p>Twenties to thirties (A)</p> Signup and view all the answers

Which of the following is NOT part of the diagnostic criteria for subjective cognitive decline?

<p>Evidence of objective cognitive impairment (D)</p> Signup and view all the answers

What percentage of individuals with Subjective Cognitive Decline (SCD) is projected to progress to Mild Cognitive Impairment (MCI)?

<p>27% (B)</p> Signup and view all the answers

Which factor is NOT considered a predictor of Mild Cognitive Impairment (MCI)?

<p>Low socioeconomic status (C)</p> Signup and view all the answers

What is the primary management approach for individuals diagnosed with SCD?

<p>Reassurance about normal cognition (C)</p> Signup and view all the answers

What percentage of individuals over 65 are estimated to experience Mild Cognitive Impairment (MCI)?

<p>11-17% (B)</p> Signup and view all the answers

Which of the following is a characteristic of Mild Cognitive Impairment (MCI)?

<p>Cognitive decline not evident in functional tasks (A)</p> Signup and view all the answers

What is the approximate percentage of individuals with MCI who develop dementia within five years?

<p>45% (B)</p> Signup and view all the answers

Which statement about dementia is true?

<p>It affects cognitive or behavioral functionality, leading to decline. (C)</p> Signup and view all the answers

What is NOT a feature of the diagnostic criteria for Mild Cognitive Impairment (MCI)?

<p>Significant impairment in daily functioning. (C)</p> Signup and view all the answers

Which non-pharmacological intervention has shown significant improvement for individuals with MCI?

<p>Cognitive training programs (B)</p> Signup and view all the answers

Which group is predicted to have a higher risk of converting from MCI to dementia?

<p>Individuals with MCI and depression (A)</p> Signup and view all the answers

What is one of the most significant risk factors for dementia?

<p>Previous/repeated traumatic brain injury (TBI) (D)</p> Signup and view all the answers

Which subtype of dementia typically has an insidious onset after the age of 65?

<p>Alzheimer's Disease (D)</p> Signup and view all the answers

What is a protective factor against dementia?

<p>Mediterranean diet (D)</p> Signup and view all the answers

What differentiates the cognitive pattern of Vascular Cognitive Impairment (VCI) from Alzheimer's Disease (AD)?

<p>VCI typically presents with a frontosubcortical pattern of deficits (B)</p> Signup and view all the answers

Which of the following is NOT a typical symptom of Alzheimer's Disease?

<p>Difficulty with movement (A)</p> Signup and view all the answers

What is one of the characteristic neuroanatomical changes found in Alzheimer's Disease?

<p>Presence of senile/amyloid plaques (B)</p> Signup and view all the answers

Which statement is true regarding Dementia with Lewy Bodies?

<p>Visual hallucinations are a common feature. (B)</p> Signup and view all the answers

What cognitive dysfunction is the first symptom typically associated with Alzheimer's Disease?

<p>Memory impairment (D)</p> Signup and view all the answers

What kind of decline is often associated with Vascular Cognitive Impairment?

<p>Step-wise decline often associated with strokes (B)</p> Signup and view all the answers

Which is a common comorbidity found with Alzheimer's Disease?

<p>Cerebrovascular pathology (D)</p> Signup and view all the answers

What type of deficits are typically seen in dementia with Lewy Bodies?

<p>Visuospatial deficits (C)</p> Signup and view all the answers

Which factors can influence the modification of dementia risk?

<p>Years of formal education and physical activity (D)</p> Signup and view all the answers

What characterizes the diagnosis process for Alzheimer’s Disease?

<p>Alzheimer's clinical syndrome is noted until plaques are confirmed. (B)</p> Signup and view all the answers

What is the primary distinction between mild cognitive impairment and dementia?

<p>Dementia involves objective cognitive deficits impacting daily living. (C)</p> Signup and view all the answers

Which of the following statements best represents normal age-related cognitive decline?

<p>Processing speed typically begins to decline significantly during middle age. (D)</p> Signup and view all the answers

What factors could contribute to subjective cognitive decline in individuals over 60 years old?

<p>Increased media coverage on dementia and societal attitudes toward aging. (C)</p> Signup and view all the answers

Which cognitive abilities remain stable throughout an individual's life, despite the aging process?

<p>Autobiographical memory and procedural memory. (B)</p> Signup and view all the answers

Flashcards

Dementia

Cognitive impairments severe enough to impact daily life.

Mild Cognitive Impairment

Cognitive deficits noticeable on testing, but not interfering with daily life.

Subjective Cognitive Decline

Feeling a decline in cognitive abilities, but no objective evidence of impairment.

Normal Age-Related Cognitive Decline

Expected cognitive changes associated with aging, with some abilities declining more than others.

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Preclinical Dementia

People who will likely develop dementia, even though at that point there aren't any evident issues.

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Subjective Cognitive Decline (SCD)

Experiencing a perceived decline in memory, but not affecting daily life, compared to past performance.

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Mild Cognitive Impairment (MCI)

Cognitive decline greater than expected for age/education, but not affecting daily life.

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Dementia

Progressive, neurodegenerative disorder causing cognitive decline and functional impairment.

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Predictors of SCD to MCI/Dementia

Factors associated with SCD progressing to MCI or dementia.

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Prevalence of MCI

The percentage of individuals over 65 with Mild Cognitive Impairment.

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Predictors of MCI to Dementia

Factors suggesting MCI might progress to dementia.

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Diagnostic Criteria for MCI

Standards for diagnosing MCI, now including multiple cognitive domains.

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Management of SCD

Strategies for managing Subjective Cognitive Decline, primarily reassurance and promoting healthy aging.

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Management of MCI

Strategies for managing Mild Cognitive Impairment, focusing on lifestyle and reversible factors.

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Management of Dementia

Strategies for managing dementia, often involving medication and support for the person and family.

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Behavioural-Variant FTD

A form of frontotemporal dementia characterized by significant behavioral changes rather than prominent cognitive problems.

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Neuropsych Exam of FTD

Neuropsychological assessment might show less problems in structured test settings; however, behavioural markers suggestive of executive dysfunction are key diagnostic tools, through interviews with both patients and caregivers

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Parkinsonian Movements in FTD

Motor symptoms in frontotemporal dementia, including shuffling gait, falls, rigidity, and slowness of movement.

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Cognitive Profile - FTD

FTD often includes significant executive dysfunction (problem with planning and decision-making) but may not be immediately obvious on tests.

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FTD Diagnosis

Diagnosis of FTD focuses on behavioral changes like inappropriate actions, emotional blunting, repetitive behavior, and lack of insight more so than standard cognitive tests.

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SSRIs

A type of antidepressant medication that can help manage dementia-related behaviors.

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Antipsychotics

Medication used for dementia-related behavioral issues, but use can be limited due to potential side effects.

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Behaviour Support Plan

A plan that provides strategies to manage challenging behaviours in individuals with dementia, particularly in nursing homes.

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Behaviour Management

Strategies to help control challenging behaviours associated with dementia.

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Modifiable Dementia Risks

Risk factors for dementia that can be lessened or avoided with lifestyle changes.

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Previous TBI

Significant risk factor for dementia, especially those with repeated head injuries.

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Cognitive Intervention Programs

Programs that aim to stimulate cognitive function in dementia, but are less effective in advancing function due to cognitive decline.

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Alzheimer's Disease

Most common type of dementia, primarily affecting memory and later other cognitive functions.

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Vascular Dementia

Dementia caused by impaired blood flow to the brain, often from strokes or other vascular issues.

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Mixed Dementia

Dementia resulting from a combination of different types of dementia, often Alzheimer's and vascular.

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Frontotemporal Dementia

Dementia type often affecting personality, language, and behavior, causing behavioural problems.

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Lewy Body Dementia

Dementia characterised by abnormal protein deposits (Lewy bodies) in the brain, impacting movement, thinking, and behavior.

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MCI

Mild Cognitive Impairment; a transitional stage between normal aging and dementia, important for identifying dementia subtypes.

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Amyloid Plaques

Abnormal clumps of beta-amyloid protein outside neurons, disrupting brain communication in Alzheimer's.

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Neurofibrillary Tangles

Abnormal clumps of tau protein inside neurons, disrupting nutrient transport in Alzheimer's.

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Alzheimer's Cognitive Profile

Typical pattern of cognitive decline in Alzheimer's, characterized by memory loss as the initial symptom and progressing backward temporally.

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Subjective Cognitive Decline

Feeling a decline in thinking skills, but no noticeable problems in everyday life when tested.

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Mild Cognitive Impairment

Subtle problems with thinking skills that may not affect daily activities, but show up during tests

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Dementia

Significant cognitive problems affecting daily living. It's more than just normal aging.

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Normal Age-Related Cognitive Decline

Brain changes expected with age that can speed up cognitive decline.

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Preclinical Dementia

People who will likely develop dementia but don't yet have any apparent issues.

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