BDS10034 Viral Infections: Orofacial Manifestations of HIV Disease
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Questions and Answers

Which virus is believed to have originated in chimpanzees and then spread to humans, leading to the HIV 1 infection?

  • Virus Y: Sooty mangabeys to humans Species jump probably via bites or injury
  • Virus Z: Spread in humans via effects of European colonialism and urbanization
  • Virus W: Spread to US via Haiti (migration from Congo)
  • Virus X: Chimpanzee subspecies Pan troglodytes troglodytes to apes to man (correct)
  • When were the oral aspects of HIV disease first described?

  • 1980s (correct)
  • 1970s
  • 1990s
  • 1960s
  • How many years passed between the identification of HIV as the cause of AIDS and the revelation of a heterosexual AIDS epidemic in Africa?

  • 20 years
  • 25 years
  • 10 years
  • 15 years (correct)
  • When was the first therapy for AIDS, zidovudine (AZT), approved for use in the USA?

    <p>1985</p> Signup and view all the answers

    What event marked the launch of Highly Active Antiretroviral Treatment?

    <p>The Human Immune Deficiency Virus (HIV) identified as the cause of AIDS</p> Signup and view all the answers

    When was the first treatment regimen developed to reduce mother-to-child transmission of HIV?

    <p>1995</p> Signup and view all the answers

    Which country became the first developing country to provide antiretroviral therapy through its public health system?

    <p>Brazil</p> Signup and view all the answers

    What event led to the spread of HIV within Africa and across the globe starting in the 1960s?

    <p>Effects of European colonialism and urbanization</p> Signup and view all the answers

    Which organization launched the '3 x 5' initiative with the goal of reaching 3 million people in the developing world with antiretroviral therapy by 2005?

    <p>World Health Organization (WHO)</p> Signup and view all the answers

    In which year did the first major downturns in the HIV epidemic in developing countries occur?

    <p>1993</p> Signup and view all the answers

    Which therapeutic strategy for HIV disease involves the specific inhibition of HIV replication and is generally not available in the developing world?

    <p>EIs</p> Signup and view all the answers

    What percentage fall in HIV-related deaths occurred between 2005 and 2016?

    <p>48%</p> Signup and view all the answers

    Which classification system for HIV oral manifestations is outdated but provides a marker of what oral disease can arise if therapy is not given or patients are unaware of their HIV infection?

    <p>Malignancy (typically viral-related)</p> Signup and view all the answers

    Which type of fungal infection is more common in the developing world and usually correlates with CD4+ T cell count & high viral load?

    <p>Superficial candidosis</p> Signup and view all the answers

    Which viral infection is more likely in children, not common in adults, and not a strong marker of HIV disease?

    <p>HSV-1</p> Signup and view all the answers

    'Shingles' is associated with which virus and is not a strong marker of HIV?

    <p>Varicella zoster virus</p> Signup and view all the answers

    Which virus causes oral hairy leukoplakia and has a low frequency with antiretroviral therapy & reversed by antiretroviral therapy?

    <p>Epstein bar virus (EBV)</p> Signup and view all the answers

    Which type of HPV oral carriage increases in HIV disease and has a higher prevalence compared to non-HIV individuals?

    <p>HPV sub-clinical oral carriage</p> Signup and view all the answers

    Which type of HPV has no link with oral sex and reflects activation of previous Epstein bar virus infections?

    <p>Low-risk HPV infection</p> Signup and view all the answers

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