Batterjee Medical College: Basic Mycology
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Questions and Answers

What is the characteristic of the yeast form of Candida albicans?

  • It forms pseudohyphae and hyphae when part of the normal flora
  • It forms only hyphae when it invades tissue
  • It has a single, broad-based bud and a thick, refractile wall
  • It produces germ tubes when incubated in serum at 37°C (correct)

    • What is the mode of transmission of Paracoccidioides brasiliensis?

  • Through skin lesions
  • Through ingestion of contaminated food
  • Through contact with contaminated soil
  • Through inhalation of airborne conidia (correct)

    • What is the disease caused by Candida albicans?

  • Cutaneous Mycoses
  • Fungal Cell Membrane Disorder
  • Thrush, Disseminated candidiasis, Chronic mucocutaneous candidiasis (correct)
  • Paracoccidioidomycosis

    • What is a predisposing factor for Candida albicans infection?

    <p>Reduced cell-mediated immunity</p> Signup and view all the answers

    What is the natural habitat of Paracoccidioides brasiliensis?

    <p>Soil</p> Signup and view all the answers

    What is the characteristic of the thermally dimorphic yeast form of Paracoccidioides brasiliensis?

    <p>It has a single, broad-based bud and a thick, refractile wall</p> Signup and view all the answers

    What is the purpose of using KOH in the preparation of a fungal sample?

    <p>To visualize fungal structures</p> Signup and view all the answers

    What is the mechanism of action of Amphotericin B?

    <p>Disrupting the integrity of fungal cell membranes</p> Signup and view all the answers

    What is the purpose of using Sabouraud's agar in fungal laboratory diagnosis?

    <p>To allow slower-growing fungi to emerge</p> Signup and view all the answers

    What is the type of hypersensitivity response caused by the inhalation of spores of Aspergillus fumigatus?

    <p>IgE-mediated immediate hypersensitivity response</p> Signup and view all the answers

    What is the effect of aflatoxin on the p53 tumor suppressor protein?

    <p>It causes a mutation in the p53 gene</p> Signup and view all the answers

    What is the mechanism of action of Echinocandins?

    <p>Inhibiting the synthesis of D-glucan</p> Signup and view all the answers

    What is the main component of fungal cell walls?

    <p>Chitin</p> Signup and view all the answers

    What type of host defense response is typically observed in infections with Histoplasma and Coccidioides?

    <p>Granulomatous response</p> Signup and view all the answers

    Which of the following fungal toxins inhibits RNA polymerase?

    <p>Amanitin</p> Signup and view all the answers

    What is the characteristic of yeast reproduction?

    <p>Daughter cells are unequal in size</p> Signup and view all the answers

    What is the characteristic of mold reproduction?

    <p>Daughter cells are equal in size</p> Signup and view all the answers

    What is the component of fungal cell membrane?

    <p>Ergosterol</p> Signup and view all the answers

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