Batterjee Medical College: Basic Mycology

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What is the characteristic of the yeast form of Candida albicans?

It forms pseudohyphae and hyphae when part of the normal flora

It forms only hyphae when it invades tissue

It has a single, broad-based bud and a thick, refractile wall

It produces germ tubes when incubated in serum at 37°C (correct)

What is the mode of transmission of Paracoccidioides brasiliensis?

Through skin lesions

Through ingestion of contaminated food

Through contact with contaminated soil

Through inhalation of airborne conidia (correct)

What is the disease caused by Candida albicans?

Cutaneous Mycoses

Fungal Cell Membrane Disorder

Thrush, Disseminated candidiasis, Chronic mucocutaneous candidiasis (correct)

Paracoccidioidomycosis

What is a predisposing factor for Candida albicans infection?

Reduced cell-mediated immunity Signup and view all the answers

What is the natural habitat of Paracoccidioides brasiliensis?

Soil Signup and view all the answers

What is the characteristic of the thermally dimorphic yeast form of Paracoccidioides brasiliensis?

It has a single, broad-based bud and a thick, refractile wall Signup and view all the answers

What is the purpose of using KOH in the preparation of a fungal sample?

To visualize fungal structures Signup and view all the answers

What is the mechanism of action of Amphotericin B?

Disrupting the integrity of fungal cell membranes Signup and view all the answers

What is the purpose of using Sabouraud's agar in fungal laboratory diagnosis?

To allow slower-growing fungi to emerge Signup and view all the answers

What is the type of hypersensitivity response caused by the inhalation of spores of Aspergillus fumigatus?

IgE-mediated immediate hypersensitivity response Signup and view all the answers

What is the effect of aflatoxin on the p53 tumor suppressor protein?

It causes a mutation in the p53 gene Signup and view all the answers

What is the mechanism of action of Echinocandins?

Inhibiting the synthesis of D-glucan Signup and view all the answers

What is the main component of fungal cell walls?

Chitin Signup and view all the answers

What type of host defense response is typically observed in infections with Histoplasma and Coccidioides?

Granulomatous response Signup and view all the answers

Which of the following fungal toxins inhibits RNA polymerase?

Amanitin Signup and view all the answers

What is the characteristic of yeast reproduction?

Daughter cells are unequal in size Signup and view all the answers

What is the characteristic of mold reproduction?

Daughter cells are equal in size Signup and view all the answers

What is the component of fungal cell membrane?

Ergosterol Signup and view all the answers