Batterjee Medical College: Basic Mycology
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Questions and Answers

What is the characteristic of the yeast form of Candida albicans?

  • It forms pseudohyphae and hyphae when part of the normal flora
  • It forms only hyphae when it invades tissue
  • It has a single, broad-based bud and a thick, refractile wall
  • It produces germ tubes when incubated in serum at 37°C (correct)

What is the mode of transmission of Paracoccidioides brasiliensis?

  • Through skin lesions
  • Through ingestion of contaminated food
  • Through contact with contaminated soil
  • Through inhalation of airborne conidia (correct)

What is the disease caused by Candida albicans?

  • Cutaneous Mycoses
  • Fungal Cell Membrane Disorder
  • Thrush, Disseminated candidiasis, Chronic mucocutaneous candidiasis (correct)
  • Paracoccidioidomycosis

What is a predisposing factor for Candida albicans infection?

<p>Reduced cell-mediated immunity (D)</p> Signup and view all the answers

What is the natural habitat of Paracoccidioides brasiliensis?

<p>Soil (C)</p> Signup and view all the answers

What is the characteristic of the thermally dimorphic yeast form of Paracoccidioides brasiliensis?

<p>It has a single, broad-based bud and a thick, refractile wall (C)</p> Signup and view all the answers

What is the purpose of using KOH in the preparation of a fungal sample?

<p>To visualize fungal structures (D)</p> Signup and view all the answers

What is the mechanism of action of Amphotericin B?

<p>Disrupting the integrity of fungal cell membranes (B)</p> Signup and view all the answers

What is the purpose of using Sabouraud's agar in fungal laboratory diagnosis?

<p>To allow slower-growing fungi to emerge (C)</p> Signup and view all the answers

What is the type of hypersensitivity response caused by the inhalation of spores of Aspergillus fumigatus?

<p>IgE-mediated immediate hypersensitivity response (D)</p> Signup and view all the answers

What is the effect of aflatoxin on the p53 tumor suppressor protein?

<p>It causes a mutation in the p53 gene (D)</p> Signup and view all the answers

What is the mechanism of action of Echinocandins?

<p>Inhibiting the synthesis of D-glucan (A)</p> Signup and view all the answers

What is the main component of fungal cell walls?

<p>Chitin (A)</p> Signup and view all the answers

What type of host defense response is typically observed in infections with Histoplasma and Coccidioides?

<p>Granulomatous response (B)</p> Signup and view all the answers

Which of the following fungal toxins inhibits RNA polymerase?

<p>Amanitin (D)</p> Signup and view all the answers

What is the characteristic of yeast reproduction?

<p>Daughter cells are unequal in size (D)</p> Signup and view all the answers

What is the characteristic of mold reproduction?

<p>Daughter cells are equal in size (D)</p> Signup and view all the answers

What is the component of fungal cell membrane?

<p>Ergosterol (D)</p> Signup and view all the answers

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