Basic Pharmacology

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Questions and Answers

What is the study of drugs, their effects on the body, and their therapeutic applications called?

  • Pharmaceutics
  • Pharmacodynamics
  • Toxicology
  • Pharmacology (correct)

How are medications classified?

  • Their effect on the body
  • Their mechanism of action
  • Their therapeutic use
  • All of the above (correct)

What does 'MOA' stand for in the context of pharmacology?

  • Method of Analysis
  • Molecular Organization
  • Metabolic Output
  • Mechanism of Action (correct)

Grouping drugs by the condition they treat is known as their:

<p>Therapeutic Class (B)</p> Signup and view all the answers

What is the molecular structure of a drug associated with?

<p>Chemical Class (B)</p> Signup and view all the answers

Which of the following best describes pharmacokinetics?

<p>How the body processes drugs (B)</p> Signup and view all the answers

What is the process by which a drug enters the bloodstream called?

<p>Absorption (A)</p> Signup and view all the answers

Which route of administration provides 100% bioavailability?

<p>Intravenous (IV) (D)</p> Signup and view all the answers

What term refers to the transport of a drug from the bloodstream to the target tissues?

<p>Distribution (B)</p> Signup and view all the answers

What does it mean when a drug is 'protein bound'?

<p>The drug is inactive. (A)</p> Signup and view all the answers

What is the chemical alteration of a drug in the body called?

<p>Metabolism (B)</p> Signup and view all the answers

Where does the first-pass effect primarily occur?

<p>Liver (A)</p> Signup and view all the answers

What is the process of removing drugs and their metabolites from the body called?

<p>Excretion (C)</p> Signup and view all the answers

What is the primary route of excretion for drugs?

<p>Urine (D)</p> Signup and view all the answers

What is the study of the therapeutic and adverse effects of drugs called?

<p>Pharmacodynamics (B)</p> Signup and view all the answers

What happens when an agonist binds to a receptor?

<p>It produces a physiological effect. (C)</p> Signup and view all the answers

What do antagonists do?

<p>Block receptor activation (D)</p> Signup and view all the answers

What is the dose required to produce the desired effect in 50% of patients called?

<p>Effective Dose 50% (ED50) (D)</p> Signup and view all the answers

What is the dose that causes death in 50% of test subjects termed?

<p>LD50 (C)</p> Signup and view all the answers

What does a high Therapeutic Index (TI) indicate about a drug?

<p>It is relatively safe (B)</p> Signup and view all the answers

Flashcards

Pharmacology

The study of drugs, their effects on the body, and their therapeutic applications.

Mechanism of Action (MOA)

How a drug interacts with receptors, enzymes, or cell structures to produce effects.

Therapeutic Class

Grouped by the condition they treat (e.g., antihypertensives, analgesics).

Pharmacokinetics

Describes how drugs move through the body using four main processes: absorption, distribution, metabolism, and excretion.

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Absorption

The process by which a drug enters the bloodstream.

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Distribution

The transport of a drug from the bloodstream to target tissues.

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Metabolism (Biotransformation)

The chemical alteration of a drug, primarily by the liver.

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Excretion

The process of removing drugs and their metabolites from the body.

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Pharmacodynamics

Explains the therapeutic and adverse effects of drugs.

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Agonists

Bind to a receptor and produce a physiological effect.

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Antagonists

Block receptor activation.

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Therapeutic Dose (ED50)

The dose required to produce the desired effect in 50% of patients.

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Half-Life (t½)

The time required for a drug's plasma concentration to decrease by 50%.

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Loading Dose

A large initial dose to rapidly achieve a therapeutic level.

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First-Order Elimination

Most drugs follow first-order kinetics, meaning the rate of elimination is proportional to drug concentration.

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Zero-Order Elimination

A few drugs follow zero-order kinetics, meaning a constant amount is eliminated per unit time, regardless of drug concentration.

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Prescription Drugs (Rx)

Medications requiring a healthcare provider's authorization.

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Over-the-Counter Drugs (OTC)

Medications available without a prescription.

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DEA (Drug Enforcement Administration)

Enforces controlled substance laws.

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FDA (Food and Drug Administration)

Regulates prescription, OTC, biologics, and supplements.

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