16 Questions
What happens to the plasma membrane in me-size fragments?
It is disrupted
What is the role of me-size fragments in the body?
They play a pathologic role in cell injury
What happens to cellular contents in me-size fragments?
They are enzymatically digested and may leak out of the cell
What is the significance of adjacent inflammation in me-size fragments?
It is frequently present
What is the role of intact cells in the body?
They often play a physiologic role
What happens to the plasma membrane in intact cells?
It remains intact with altered structure
What is the significance of apoptotic bodies in intact cells?
They are sometimes present
What is the role of DNA damage in intact cells?
It may lead to cell injury and pathologic changes
What is the typical characteristic of cell size in necrosis?
Enlarged (swelling)
What happens to the nucleus in apoptosis?
Fragmentation into nucleosomes
What is a key distinction between necrosis and apoptosis?
Nuclear changes
In which process does karyorrhexis occur?
Necrosis
What is the outcome of karyolysis?
Nuclear dissolution
In which process does cell shrinkage occur?
Apoptosis
What is a characteristic feature of necrotic cells?
Enlarged cell size
What is a key difference between apoptosis and necrosis?
Cell size and nuclear changes
Study Notes
Cell Death
Necrosis
- Enlarged cell size (swelling)
- Pyknosis, karyorrhexis, and karyolysis of the nucleus
- Disrupted plasma membrane
- Cellular contents may leak out of the cell due to enzymatic digestion
- Often accompanied by adjacent inflammation
- Always a pathologic process (result of irreversible cell injury)
Apoptosis
- Reduced cell size (shrinkage)
- Fragmentation of the nucleus into nucleosome-sized fragments
- Intact plasma membrane with altered structure and lipid orientation
- Cellular contents remain intact and may be released in apoptotic bodies
- No adjacent inflammation
- Can be a physiologic process (elimination of unwanted cells) or pathologic (after certain types of cell injury, such as DNA damage)
Other Chapter Notes
Chapter 2
- Various points discussed (no specific key takeaways)
Chapter 10
- Multiple topics covered (no specific key takeaways)
Chapters 5, 6, 7, and 8
- No specific key takeaways or notable points mentioned
This quiz assesses your understanding of basic logic and reasoning concepts. Test your skills with these questions and improve your critical thinking.
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