Basic Blood Banking Principles Quiz
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Questions and Answers

What is the relationship between the chemical composition of an antigen and its immunogenicity?

The more complex the chemical composition of an antigen, the more immunogenic it is.

What is an antigen?

An antigen is a foreign substance that can stimulate an immune response, such as a toxin, microorganism, or any molecule that can bind to a B-cell receptor, T-cell receptor, or an antibody.

What is an immunogen?

An immunogen is an antigen that stimulates the immune response.

What are the five classes of antibodies?

<p>The five classes of antibodies are IgG, IgA, IgM, IgD, and IgE.</p> Signup and view all the answers

What are the two main characteristics of antigens that determine their immunogenicity?

<p>The two main characteristics of antigens that determine their immunogenicity are size (the larger the molecular weight/size, the more immunogenic) and complexity (the more complex the antigen, the more immunogenic).</p> Signup and view all the answers

What is a hapten?

<p>A hapten is an incomplete antigen.</p> Signup and view all the answers

What is the most abundant immunoglobulin in plasma/serum?

<p>Immunoglobulin G (IgG)</p> Signup and view all the answers

At what temperature does IgG react?

<p>IgG reacts at body temperature (37°C)</p> Signup and view all the answers

How many subclasses of IgG are there?

<p>There are 4 subclasses of IgG: IgG1, IgG2, IgG3, and IgG4.</p> Signup and view all the answers

What is the largest antibody?

<p>Immunoglobulin M (IgM) is the largest antibody.</p> Signup and view all the answers

At what temperature does IgM react?

<p>IgM reacts at ambient temperature (22-24°C).</p> Signup and view all the answers

When is the peak response for the secondary immune response?

<p>The peak response for the secondary immune response is usually 5-10 days after immunization.</p> Signup and view all the answers

What is the significance of Immunoglobulin A (IgA) in cases of anaphylactic reactions?

<p>Usually involved</p> Signup and view all the answers

Where is Immunoglobulin A (IgA) found in the body?

<p>Body fluids, secretion, serum</p> Signup and view all the answers

What can happen if Immunoglobulin A (IgA) is transfused in IgA deficient patients?

<p>Severe anaphylaxis</p> Signup and view all the answers

What is the role of Immunoglobulin E (IgE) in the body?

<p>Allergic reactions, parasitic reactions</p> Signup and view all the answers

Why is Immunoglobulin D (IgD) considered the least significant in blood banking?

<p>Least significant</p> Signup and view all the answers

What type of antibodies are derived from more than one antibody-producing parent cell?

<p>Polyclonal antibody</p> Signup and view all the answers

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