Basement Membrane and Intercellular Junctions Quiz

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What molecules self-assemble to form a lace-like sheet below the cells' basal poles?

BASEMENT MEMBRANE

What is the function of type IV collagen in junctions?

Seals to prevent the flow of materials

Which adhesive glycoprotein holds together laminin and type IV collagen in the basement membrane?

ENTACTIN/NIDOGEN and PERLECAN

What type of junctions provide channels for communication between adjacent cells?

Gap junctions Signup and view all the answers

What is the major component of anchoring fibrils in the basement membrane?

Type VII collagen Signup and view all the answers

What type of collagen forms a supporting network in the reticular lamina of the basement membrane?

Type III collagen Signup and view all the answers

What is the main function of stratified columnar epithelium?

Protection, Secretion Signup and view all the answers

Describe the appearance of transitional (urothelium) epithelium when the organ is distended.

Appear very thin Signup and view all the answers

What is the classification of glandular epithelia based on how the secretory products leave the cell?

Merocrine, Holocrine, Apocrine Signup and view all the answers

Where is the stratified columnar epithelium found in the body?

Lining of trachea, Bronchi, Nasal cavity Signup and view all the answers

Explain the variation in shape of cells in stratified columnar epithelium.

Tall columnar, Fusiform/spheroidal Signup and view all the answers

What is the main function of secretory epithelia and glands?

Secretion Signup and view all the answers

What are the two main classifications of exocrine glands based on the way secretory products leave the cell?

Merocrine and Holocrine Signup and view all the answers

Describe the secretory portion of acinar exocrine glands.

Rounded and sac-like Signup and view all the answers

Which type of gland maintains the integrity of their constituent cells throughout the process of secretion?

Merocrine glands Signup and view all the answers

Give an example of an exocrine gland that exhibits holocrine secretion.

Sebaceous glands of the skin Signup and view all the answers

What is the main difference between merocrine and holocrine secretion in terms of cell involvement?

Merocrine secretion involves minimal cell disruption, while holocrine secretion involves complete cell disruption. Signup and view all the answers

What type of cells are gap junctions present in and absent in?

Present in: between osteocytes, smooth and cardiac muscles, neurons; Absent in: skeletal muscle, blood Signup and view all the answers

What is the mutation associated with congenital disease related to Connexin 26?

Mutation of Connexin 26 Signup and view all the answers

Which exocrine gland type is characterized by the release of spermatozoa in the testis?

Holocrine glands Signup and view all the answers

What is the role of Junction Desmosome in cells?

Provides points of strong intermediate coupling between adjacent cells, strengthening the tissue. Signup and view all the answers

What are the major transmembrane proteins involved in Junction Desmosome?

Cadherin family proteins (desmoglein s, desmocollin) Signup and view all the answers

What cytoskeletal components are associated with Junction Desmosome?

Intermediate filaments (keratin) Signup and view all the answers

What is the major function of Gap Junctions?

Allow transfer of small molecules and ions from one cell to other. Signup and view all the answers

What is the main function of stereocilia found in the lining epithelium of the epididymis and proximal part of the ductus deferens?

Promote absorption by amplifying cell surface like the microvilli Signup and view all the answers

How do basal infoldings contribute to the function of epithelial cells?

Increases the surface area at the base of a cell promoting absorption like the microvilli Signup and view all the answers

What is the difference between primary cilium and motile cilia in terms of motility?

Primary cilium is non-motile while motile cilia are capable of movement Signup and view all the answers

What important role does nodal play in embryonic development?

Nodal plays an important role in embryonic development Signup and view all the answers

Where are simple squamous epithelium cells typically found?

Endothelium Signup and view all the answers

What are the main groups for the classification of epithelia based on function?

Covering (lining) epithelia and Secretory (glandular) epithelia Signup and view all the answers

Basement Membrane Molecules

Molecules that self-assemble to form a lace-like sheet below cells' basal poles.

Type IV Collagen Function

Seals junctions, preventing material flow.