Podcast
Questions and Answers
Which of the following is a key neurotransmitter system implicated in the pathophysiology of schizophrenia?
Which of the following is a key neurotransmitter system implicated in the pathophysiology of schizophrenia?
- Serotonergic system
- Noradrenergic system
- Cholinergic system
- Dopaminergic system (correct)
What type of receptor is primarily responsible for the rapid, excitatory effects of the neurotransmitter glutamate in the central nervous system?
What type of receptor is primarily responsible for the rapid, excitatory effects of the neurotransmitter glutamate in the central nervous system?
- Kainate receptor
- NMDA receptor
- Metabotropic glutamate receptor
- AMPA receptor (correct)
Which of the following is considered a leading genetic risk factor for the development of schizophrenia?
Which of the following is considered a leading genetic risk factor for the development of schizophrenia?
- Overexpression of the APOE gene
- Polymorphism in the DRD2 gene
- Deletion in the 22q11.2 chromosomal region (correct)
- Mutation in the BRCA1 gene
Which of the following neurotransmitter receptors is considered a potential therapeutic target for the treatment of cognitive deficits in schizophrenia?
Which of the following neurotransmitter receptors is considered a potential therapeutic target for the treatment of cognitive deficits in schizophrenia?
Which of the following is a proposed mechanism by which environmental factors, such as maternal infection during pregnancy, may increase the risk of developing schizophrenia?
Which of the following is a proposed mechanism by which environmental factors, such as maternal infection during pregnancy, may increase the risk of developing schizophrenia?
Which of the following is a key mechanism by which antipsychotic medications exert their therapeutic effects in the treatment of schizophrenia?
Which of the following is a key mechanism by which antipsychotic medications exert their therapeutic effects in the treatment of schizophrenia?
Which gene is involved in modulating hippocampal synaptic plasticity and behavior in schizophrenia?
Which gene is involved in modulating hippocampal synaptic plasticity and behavior in schizophrenia?
Which gene is responsible for breakdown of extracellular matrix in normal physiological processes related to schizophrenia?
Which gene is responsible for breakdown of extracellular matrix in normal physiological processes related to schizophrenia?
Which gene is associated with neuron development and synapse formation in the context of schizophrenia?
Which gene is associated with neuron development and synapse formation in the context of schizophrenia?
Which gene enables protein-macromolecule adaptor activity and is involved in negative regulation of transcription in schizophrenia?
Which gene enables protein-macromolecule adaptor activity and is involved in negative regulation of transcription in schizophrenia?
What function do proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner in schizophrenia?
What function do proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner in schizophrenia?
Which gene is involved in the initiation of neuronal differentiation related to schizophrenia?
Which gene is involved in the initiation of neuronal differentiation related to schizophrenia?
What is the main excitatory neurotransmitter in the CNS?
What is the main excitatory neurotransmitter in the CNS?
Which neurotransmitter is associated with the reward system through CB1R activation?
Which neurotransmitter is associated with the reward system through CB1R activation?
In schizophrenia, what pathway is associated with positive symptoms like hallucinations and delusions?
In schizophrenia, what pathway is associated with positive symptoms like hallucinations and delusions?
Which of the following is NOT a symptom associated with schizophrenia psychopathology?
Which of the following is NOT a symptom associated with schizophrenia psychopathology?
What is the possible cause of schizophrenia related to neurotransmitters?
What is the possible cause of schizophrenia related to neurotransmitters?
Which ionotropic receptor type is implicated in schizophrenia, particularly in relation to dopamine imbalance?
Which ionotropic receptor type is implicated in schizophrenia, particularly in relation to dopamine imbalance?
