Barbiturates

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Questions and Answers

Which organ system is minimally affected by benzodiazepines, even at high doses of general anesthetics?

  • Muscular
  • Cerebral
  • Cardiovascular (correct)
  • Respiratory

What effect do benzodiazepines have on blood pressure when administered alone?

  • Increase
  • Fluctuate
  • No effect
  • Decrease (correct)

Which organ system do benzodiazepines primarily affect in terms of reducing cerebral oxygen consumption and intracranial pressure?

  • Cerebral (correct)
  • Cardiovascular
  • Muscular
  • Respiratory

Which receptor do barbiturates bind to in the brain?

<p>GABAA receptor (D)</p> Signup and view all the answers

What determines the hypnotic potency and anticonvulsant activity of barbiturates?

<p>The substitution at the C5 carbon (C)</p> Signup and view all the answers

Which barbiturate has greater lipid solubility due to the substitution of an oxygen atom at C2?

<p>Thiopental (D)</p> Signup and view all the answers

Which of the following is true about the excretion of barbiturates?

<p>Barbiturates are primarily excreted in the feces (B)</p> Signup and view all the answers

What effect do barbiturates have on the cerebral vasculature?

<p>Barbiturates cause a decrease in cerebral blood flow (A)</p> Signup and view all the answers

Which of the following is true about the renal effects of barbiturates?

<p>Barbiturates decrease glomerular filtration rate (D)</p> Signup and view all the answers

Which of the following is true about the distribution of benzodiazepines in the body?

<p>Benzodiazepines easily penetrate the blood-brain barrier (A)</p> Signup and view all the answers

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