10 Questions
Which organ system is minimally affected by benzodiazepines, even at high doses of general anesthetics?
Cardiovascular
What effect do benzodiazepines have on blood pressure when administered alone?
Decrease
Which organ system do benzodiazepines primarily affect in terms of reducing cerebral oxygen consumption and intracranial pressure?
Cerebral
Which receptor do barbiturates bind to in the brain?
GABAA receptor
What determines the hypnotic potency and anticonvulsant activity of barbiturates?
The substitution at the C5 carbon
Which barbiturate has greater lipid solubility due to the substitution of an oxygen atom at C2?
Thiopental
Which of the following is true about the excretion of barbiturates?
Barbiturates are primarily excreted in the feces
What effect do barbiturates have on the cerebral vasculature?
Barbiturates cause a decrease in cerebral blood flow
Which of the following is true about the renal effects of barbiturates?
Barbiturates decrease glomerular filtration rate
Which of the following is true about the distribution of benzodiazepines in the body?
Benzodiazepines easily penetrate the blood-brain barrier
Test your knowledge on barbiturates and their mechanism of action in this quiz. Learn about their effects on the brain's reticular activating system and their interaction with the GABAA receptor.
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