Barbiturates: mechanisms, medications, and effects
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Questions and Answers

Which of the following is a mechanism of action for barbiturates?

  • Stimulating neuronal impulse conduction in the ascending RAS, depressing the CNS.
  • Enhancing neuronal impulse conduction in the descending RAS, stimulating the CNS.
  • Inhibiting hormone production in the pituitary gland.
  • Inhibiting neuronal impulse conduction in the ascending RAS, depressing the CNS. (correct)

Which of the following medications is a barbiturate?

  • Lorazepam
  • Haloperidol
  • Fluoxetine
  • Phenobarbital (correct)

Which of the following conditions is a contraindication for barbiturate use?

  • Latent Porphyria (correct)
  • Diabetes
  • Hypertension
  • Hyperlipidemia

What is a common adverse effect associated with barbiturates?

<p>Sedation (C)</p> Signup and view all the answers

Which substance, when taken with barbiturates, could lead to increased CNS depression?

<p>Alcohol (C)</p> Signup and view all the answers

Flashcards

Barbiturates: Mechanism of Action

Inhibits neuronal impulse conduction in the ascending RAS, depressing the CNS.

Barbiturates: Indications

Anxiety disorders, pre-anesthesia seizures, sedation, acute manic reactions, and insomnia.

Barbiturates: Contraindications

Latent/manifest porphyria, liver/kidney dysfunction, respiratory distress, and pregnancy.

Barbiturates: Adverse Effects

Sedation, drowsiness, ataxia, hallucinations, N/V, cardiovascular & respiratory depression, Steven-Johnson Syndrome.

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Barbiturates: Drug-Drug Interactions

Alcohol, anticoagulants, digoxin, and contraceptives.

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