36 Questions
What is the expected percentage of adult obesity in the US by 2030?
50%
Which factor is NOT listed as a determinant of weight gain in the learning objectives?
Social
What is the most common age range affected by adult obesity according to the background information?
40-59 years old
What is the current percentage of adult obesity in the US?
41.9%
Which population is disproportionately affected by adult obesity according to the background information?
Black
Which guideline is mentioned for the management of overweight and obesity in adults?
2013 AHA/ACC/TOS Guideline
What is the additional annual cost attributed to adult obesity according to the text?
$1,861/year
What is the formula to calculate energy balance?
Energy balance = intake + storage - output
Which hormone acts as a common appetite suppressor?
Leptin
What is the impact of obesity on drug metabolism and excretion?
Decrease in glomerular filtration and tubular reabsorption
What is the additional annual cost of metabolic syndrome due to obesity?
$2,200/year
How much weight loss is associated with lowering A1c by 0.6 to 1% in Type 2 Diabetes Mellitus?
5-10%
What benefit is associated with a 3 kg (6.6 lbs) weight loss in hyperlipidemia?
15 mg/dL reduction in triglycerides
Which guideline focuses on treatment based on BMI?
2013 AHA/ACC/TOS
What type of therapy recommends keeping the calorie deficit below 800 kcal/day for severely obese people?
Very Low Calorie Diet Style
Which diet style is dangerous for patients with diabetes?
Low Carb Diet Style
What does a Low Calorie diet style recommend for energy deficit?
1200 - 1500 kcal/day energy deficit for women, 1500 - 1800 kcal/day for men
What is the recommended evaluation strategy for discontinuing Liraglutide (Saxenda) if 5% weight loss is not achieved?
Discontinue if 5% weight loss is not achieved at 12 weeks of max tolerated dose
Which GLP-1 Agonist has the longest duration for storing the opened pen at room temperature?
Saxenda (liraglutide) → 30 days
Which medication class may lead to weight gain according to the medication reconciliation information provided?
Antipsychotics
What is the primary determinant of body weight according to the lecture summary?
Genetic factors
Which bariatric surgery classification bypasses a portion of the intestine to limit nutrient absorption?
Biliopancreatic Diversion + Duodenal Switch Bypass
Which GLP-1 Agonist has the same active ingredient as Ozempic and Rybelsus for T2DM?
Wegovy (semaglutide)
What is the primary risk associated with dumping syndrome after malabsorptive surgeries?
Vasomotor due to accelerated emptying of hyperosmolar content into the small intestine
What type of surgery reduces the size of the stomach to limit the amount of food that can be consumed at one time?
Adjustable Gastric Band
Which natural product's safety & efficacy are undetermined?
5-Hydroxytryptophan
What is the recommended daily calorie intake range for men to achieve weight loss?
1500-1800 kcal/day
Which drug has been associated with an increased risk of heart attack and strokes?
Belviq
What is the mechanism of action of lipase inhibitor Orlistat?
Inhibition of dietary fat absorption by 30%
Which combination drug includes naltrexone as an opioid antagonist?
Contrave
What is the main mechanism of action of phentermine/topiramate (Qsymia)?
Suppresses appetite and increases satiety
Which condition is a contraindication for using sympathomimetics for weight loss?
Glaucoma
What is the main boxed warning associated with the use of lipase inhibitor Orlistat?
Oily rectal leakage and related gastrointestinal side effects
Which drug has a boxed warning related to thyroid C-cell tumor risk?
[Saxenda]
Which condition warrants caution when using sympathomimetics for weight loss?
[Heart failure]
Which diet style has evidence from 2 RCTs supporting weight loss and lowering blood pressure?
DASH Diet
Learn about balanced deficit diets and their role in achieving weight loss, with a focus on energy deficit requirements and recommended calorie intake. Explore different diet styles such as the Mediterranean Diet, Vegan, or Vegetarian, supported by evidence from randomized controlled trials (RCTs) for weight loss and reduced risk of major cardiovascular events.
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