Bacterial Structure and Organization Quiz
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Questions and Answers

What is the general organization of a bacterial cell?

  • Cell membrane and cytoplasm (correct)
  • Cell membrane, cytoplasm, and flagella
  • Cell wall, cytoplasm, and pili
  • Cell membrane, cell wall, and capsule

Which bacterial structure is responsible for protecting the cell from lysis due to changes in osmotic pressure?

  • Flagella
  • Periplasm
  • Pili/fimbriae
  • Capsule (correct)

What is the main function of the bacterial cell wall?

  • Provide structural support and shape to the cell (correct)
  • Facilitate cellular locomotion
  • Regulate the entry of nutrients into the cell
  • Facilitate genetic exchange between cells

Which component of the bacterial cell envelope is associated with adherence to host cells and tissues?

<p>Pili/fimbriae (B)</p> Signup and view all the answers

What is the function of the plasma membrane in bacteria?

<p>Barrier against aqueous ions (B)</p> Signup and view all the answers

What is the main function of peptidoglycan?

<p>Structural support and shape (A)</p> Signup and view all the answers

Where is cardiolipin found in bacteria?

<p>In the plasma membrane (D)</p> Signup and view all the answers

Which components of the bacterial cell wall differ between different types and species of bacteria?

<p>Peptidoglycan layer (B)</p> Signup and view all the answers

What is the main function of the outer membrane in Gram-negative bacteria and Chlamydiaceae?

<p>Selective barrier and protection against lysis (C)</p> Signup and view all the answers

What is present in the outer leaflet of the outer membrane?

<p>Lipopolysaccharide (LPS) (D)</p> Signup and view all the answers

How does the outer membrane contribute to host mimicry and antigenic variation?

<p>Via sugars (O-antigen) and proteins (D)</p> Signup and view all the answers

What is the function of the periplasm in bacteria?

<p>Protection against osmotic lysis via solutes (C)</p> Signup and view all the answers

What is the major function of capsules in bacteria?

<p>Antiphagocytic activity (B)</p> Signup and view all the answers

Which component is responsible for adhesion to surfaces and biofilm formation in bacteria?

<p>Slime (A)</p> Signup and view all the answers

What is the main function of pili/fimbriae in bacteria?

<p>Adhesion to host cell receptors (B)</p> Signup and view all the answers

What is the role of the 'K' antigen in some serotyping schemes of bacteria?

<p>Vaccine target (D)</p> Signup and view all the answers

Which drug prevents the recycling of bactoprenol-PP during peptidoglycan synthesis?

<p>Bacitracin (C)</p> Signup and view all the answers

What is inhibited by Fosfomycin during peptidoglycan synthesis?

<p>MurA (C)</p> Signup and view all the answers

Which drug inhibits alanine racemase and D-ala-D-ala synthetase during peptidoglycan synthesis?

<p>Cycloserine (A)</p> Signup and view all the answers

What does Tunicamycin prevent during peptidoglycan synthesis?

<p>NAM-P to Und-P transfer (D)</p> Signup and view all the answers

Which antibacterial enzyme cleaves the bond between NAG and NAM in peptidoglycan?

<p>Lysozyme (C)</p> Signup and view all the answers

What is the primary function of the plasma membrane in bacteria?

<p>Control over osmotic balance (B)</p> Signup and view all the answers

Which component forms a 3D multilayered net in the peptidoglycan structure?

<p>Peptide tail (A)</p> Signup and view all the answers

What is the role of cardiolipin in the plasma membrane of bacteria?

<p>Barrier against aqueous ions (D)</p> Signup and view all the answers

Where is the outer membrane absent in some genera or species of bacteria?

<p>Gram-positive bacteria (D)</p> Signup and view all the answers

What type of bacteria has a variable outer membrane structure used for differentiating strains or species?

<p>Gram-negative bacteria (D)</p> Signup and view all the answers

What is added in phase II of PG biosynthesis in the presence of a bridge peptide?

<p>Pentaglycine bridge (A)</p> Signup and view all the answers

Where does monomer production for PG biosynthesis occur?

<p>Cytoplasm (C)</p> Signup and view all the answers

What is used for the production of many extracellular polysaccharides in phase I of PG biosynthesis?

<p>Bactoprenol-PP (C)</p> Signup and view all the answers

What is responsible for incorporating the new monomer into the PG macromolecule in phase III of PG biosynthesis?

<p>Transglycosylases (C)</p> Signup and view all the answers

Which type of drug inhibits transpeptidases and leads to cell lysis as autolysins continue to function by weakening the new peptidoglycan?

<p>$\beta$-lactams (penicillins, cephalosporins, etc.) (D)</p> Signup and view all the answers

Which of the following bacterial genera is Gram-negative?

<p>Salmonella (B)</p> Signup and view all the answers

What is a characteristic feature of the outer membrane of Gram-negative bacteria?

<p>Containment of crystal violet during Gram staining (B)</p> Signup and view all the answers

Which type of bacteria has a cell wall structure that includes mycolic acids?

<p>Mycobacterium (D)</p> Signup and view all the answers

Which staining technique is specifically used for acid-fast bacteria?

<p>Ziehl-Neelsen stain (D)</p> Signup and view all the answers

Which bacterial genus is known for its resistance to chemicals and antibiotics due to its unique cell wall components?

<p>Bacteroides (D)</p> Signup and view all the answers

What is the main function of Penicillin-binding proteins (PBPs) in the peptidoglycan (PG) biosynthetic process?

<p>Cleaving PG crosslinks to allow cell growth and separation (A)</p> Signup and view all the answers

Which bacteria have an outer membrane with lipopolysaccharides (LPS) but no peptidoglycan (PG)?

<p>Chlamydia and Chlamydophila (A)</p> Signup and view all the answers

What is the main role of the protein layer in the context of bacterial cell wall biosynthesis?

<p>Providing structural support to the bacterial cell wall (B)</p> Signup and view all the answers

Why is the Gram stain not useful for visualizing spirochetes such as Treponema and Borrelia?

<p>They have a very thin structure that is not visible by light microscopy (D)</p> Signup and view all the answers

Which enzyme is responsible for removing the last D-alanine from peptide tails that have not been crosslinked in peptidoglycan (PG)?

<p>DD-carboxypeptidase (C)</p> Signup and view all the answers

What is the main function of peptidoglycan in bacteria?

<p>Protection against osmotic lysis (A)</p> Signup and view all the answers

Which statement best describes the biological effects of peptidoglycan?

<p>Unique to bacteria and induces cytokines (C)</p> Signup and view all the answers

What role do teichoic and lipoteichoic acids play in Gram-positive bacteria?

<p>Regulation of autolysis (B)</p> Signup and view all the answers

Which bacterial component is involved in adherence to host cells and tissues?

<p>Peptidoglycan (B)</p> Signup and view all the answers

What is the general role of adhesins in bacteria?

<p>Facilitating adherence to host cells and tissues (A)</p> Signup and view all the answers

Which component is a specific type of peptidoglycan fragment targeting ciliated respiratory epithelial cells?

<p>Cytotoxin (B)</p> Signup and view all the answers

What is the primary effect of teichoic and lipoteichoic acids in Gram-positive bacteria?

<p>Regulation of autolysis (B)</p> Signup and view all the answers

What is the function of PAMPs (Pathogen Associated Molecular Patterns) in bacteria?

<p>Inducing cytokines like IL-1, IL-6, GCSF, TNF (D)</p> Signup and view all the answers

What distinguishes teichoic and lipoteichoic acids from peptidoglycan in their role within Gram-positive bacteria?

<p>Regulation of autolysis (A)</p> Signup and view all the answers

What is the key function of adhesins in bacteria?

<p>Facilitating adherence to host cells and tissues (C)</p> Signup and view all the answers

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