Bacterial Cystitis Diagnosis Quiz

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What are the cardinal signs of lower urinary tract disease?

Polyuria, Pollakiuria, and Incontinence

Which part of the urinary tract is responsible for localizing the disease to the upper urinary tract?

Kidneys

What is the definition of polyuria?

Increased volume of urine

What is the main goal of differentiating urinary tract infections from subclinical bacteriuria?

<p>To generate a treatment plan</p> Signup and view all the answers

What is the most common cause of pyelonephritis?

<p>Ascending bacterial infections from the lower urinary tract</p> Signup and view all the answers

Which of the following is a potential clinical sign of pyelonephritis?

<p>Polyuria/polydipsia</p> Signup and view all the answers

What is a potential predisposing factor for pyelonephritis?

<p>Urethral abnormalities</p> Signup and view all the answers

Which diagnostic test is most definitive for pyelonephritis?

<p>Pyelocentesis</p> Signup and view all the answers

What is the recommended treatment for pyelonephritis?

<p>Empiric antibiotic therapy based on culture and sensitivity results</p> Signup and view all the answers

What is a potential consequence of chronic, untreated pyelonephritis?

<p>Chronic kidney disease</p> Signup and view all the answers

What is the most likely cause of the bacteriuria in the given case?

<p>Pyelonephritis</p> Signup and view all the answers

What is the most definitive finding in abdominal ultrasound for pyelonephritis?

<p>Pyelectasia</p> Signup and view all the answers

What type of medication is commonly used in the treatment of pyelonephritis?

<p>Fluoroquinolone</p> Signup and view all the answers

What is a potential sign of systemic illness in pyelonephritis?

<p>Fever</p> Signup and view all the answers

What is a potential evidence of comorbidity/predisposing factor in urinalysis for pyelonephritis?

<p>Glucosuria</p> Signup and view all the answers

What is a potential consequence of untreated pyelonephritis?

<p>Permanent renal injury</p> Signup and view all the answers

What is the most appropriate treatment time for reinfection of bacterial cystitis?

<p>3-5 days</p> Signup and view all the answers

What is the recommended treatment for recurrent bacterial cystitis if the infection is resistant to empiric antibiotic?

<p>Continue empiric antibiotic if animal is clinically responding</p> Signup and view all the answers

What is the appropriate initial treatment time for reinfection of pyelonephritis?

<p>3-5 days</p> Signup and view all the answers

What is the most appropriate empiric therapy for a 2 yo FS Bulldog with UTI caused by E. coli?

<p>Amoxicillin for 5 days</p> Signup and view all the answers

What is the appropriate treatment time for relapse or persistence of bacterial cystitis?

<p>7-14 days</p> Signup and view all the answers

What is the most common reason for isolates with < 1,000 CFUs in urine culture?

<p>Contamination</p> Signup and view all the answers

What is the appropriate treatment for recurrent bacterial cystitis if the animal is not responding within 48 hours?

<p>Further investigation</p> Signup and view all the answers

What should be considered before selecting a drug for multi-drug resistant organisms causing UTI?

<p>Regional resistance patterns</p> Signup and view all the answers

What is the appropriate follow-up for sporadic bacterial cystitis?

<p>Correct/manage predisposing conditions</p> Signup and view all the answers

What is the most appropriate treatment for sporadic bacterial cystitis if the infection is resistant to empiric antibiotic?

<p>Switch to culture and susceptibility-based antibiotic</p> Signup and view all the answers

What is the recommended initial treatment time for reinfection of pyelonephritis?

<p>3-5 days</p> Signup and view all the answers

What is the appropriate treatment for recurrent bacterial cystitis if the infection is resistant to empiric antibiotic?

<p>Continue empiric antibiotic if animal is clinically responding</p> Signup and view all the answers

What are the three cardinal signs of lower urinary tract disease?

<p>Polyuria, pollakiuria, stranguria</p> Signup and view all the answers

What is the most common cause of urinary tract infections (UTIs) in dogs?

<p>Bacteria</p> Signup and view all the answers

Which anatomical structure's impairment predisposes to UTIs?

<p>Glycosaminoglycans</p> Signup and view all the answers

What is the definitive method for diagnosing a urinary tract infection (UTI)?

<p>Quantitative urine culture</p> Signup and view all the answers

Which organisms are commonly associated with bacterial cystitis in dogs?

<p>Gram-negative organisms</p> Signup and view all the answers

What clinical signs indicate upper urinary tract infection (pyelonephritis)?

<p>Fever, inappetence, vomiting, lethargy</p> Signup and view all the answers

What does pyuria (> 3-5 WBCs/hpc) indicate in a urinalysis?

<p>Supportive evidence for UTI</p> Signup and view all the answers

What can be mistaken for bacteriuria in a urinalysis?

<p>Stain precipitate</p> Signup and view all the answers

What is the most common cause of UTIs in cats?

<p>E. coli</p> Signup and view all the answers

What percentage of positive urine cultures in cats are Enterococcus spp.?

<p>27%</p> Signup and view all the answers

What can indicate non-urinary systemic disease in the case of polymicrobial infections?

<p>Fever, inappetence, vomiting, lethargy</p> Signup and view all the answers

What is the most common cause of polymicrobial infections in dogs?

<p>Bacterial cystitis</p> Signup and view all the answers

What is the most appropriate drug to prescribe for a 12-year-old male neutered Cocker Spaniel found to be proteinuric (UPC 3.2) and hypertensive (BP 170 mmHg) on routine geriatric panel?

<p>Amlodipine</p> Signup and view all the answers

Which antiplatelet drug is generally used in the management of hypercoagulability?

<p>Clopidogrel</p> Signup and view all the answers

Which factor Xa inhibitor is mentioned in the text for the management of hypercoagulability?

<p>Rivaroxaban</p> Signup and view all the answers

What are the mild diuretics mentioned in the text for managing fluid accumulation?

<p>Spironolactone</p> Signup and view all the answers

In the treatment of underlying glomerular disease, how often should monitoring be conducted initially?

<p>Every 2-4 weeks</p> Signup and view all the answers

Which drug is mentioned in the text as an immunosuppressive protocol for glomerulopathies?

<p>Mycophenolate mofetil</p> Signup and view all the answers

What is a negative prognostic indicator for glomerular disease in dogs?

<p>Azotemia</p> Signup and view all the answers

Which drug is most appropriate to prescribe for hypertension in a proteinuric dog?

<p>Amlodipine</p> Signup and view all the answers

What is the main cause of glomerular (renal) proteinuria?

<p>Abnormal filtration by the glomerulus</p> Signup and view all the answers

Which type of glomerular disease is the most common, causing damage to the glomerular filtration apparatus?

<p>Immune-complex glomerulonephritis (ICGN)</p> Signup and view all the answers

What are the potential complications of glomerular diseases?

<p>Hypertension, hypercoagulability, and fluid accumulation</p> Signup and view all the answers

What type of proteinuria results from excess plasma proteins exceeding resorption in proximal renal tubules?

<p>Pre-renal proteinuria</p> Signup and view all the answers

Which type of glomerular disease causes damage to the glomerular filtration barrier?

<p>Glomerulosclerosis</p> Signup and view all the answers

What is the potential cause of post-renal proteinuria?

<p>Inflammation below the collecting duct</p> Signup and view all the answers

What are the types of glomerular diseases?

<p>Functional and structural</p> Signup and view all the answers

What is the cause of renal proteinuria?

<p>Diseases affecting the proximal tubules</p> Signup and view all the answers

Which type of glomerular disease is due to abnormal filtration by the glomerulus?

<p>Immune-complex glomerulonephritis (ICGN)</p> Signup and view all the answers

What are the potential consequences of glomerular diseases?

<p>Hypertension, hypercoagulability, and fluid accumulation</p> Signup and view all the answers

What is the cause of glomerular (renal) proteinuria?

<p>Abnormal filtration by the glomerulus</p> Signup and view all the answers

What is the main type of proteinuria caused by diseases affecting the proximal tubules?

<p>Renal proteinuria</p> Signup and view all the answers

Which of the following is a hallmark of glomerular disease?

<p>Proteinuria</p> Signup and view all the answers

What is the screening test for proteinuria in diagnosing glomerular disease?

<p>Urine protein:creatinine ratio (UPC)</p> Signup and view all the answers

Which of the following is a common finding in glomerular disease?

<p>Hypoalbuminemia</p> Signup and view all the answers

What is essential for managing proteinuria and its complications in glomerular disease?

<p>Sodium restriction</p> Signup and view all the answers

What is the adverse effect of Angiotensin Converting Enzyme Inhibitors (ACEi) and Angiotensin Receptor Blockers (ARBs)?

<p>Hyperkalemia</p> Signup and view all the answers

What is crucial for reducing intraglomerular pressures and magnitude of proteinuria in glomerular disease?

<p>RAAS blockade</p> Signup and view all the answers

What is necessary for distinguishing between primary glomerular diseases in glomerular disease diagnosis?

<p>Renal biopsy</p> Signup and view all the answers

What is essential for confirming proteinuria and identifying non-renal causes of hypertension in glomerular disease?

<p>Advanced diagnostics</p> Signup and view all the answers

What helps reduce proteinuria by inhibiting AngII production and blocking its receptor in glomerular disease management?

<p>RAAS blockade</p> Signup and view all the answers

What is essential for successful management of glomerular disease?

<p>Identifying and treating the underlying disease</p> Signup and view all the answers

What may be necessary to distinguish between primary glomerular diseases and look for an underlying cause in glomerular disease diagnosis?

<p>Renal biopsy</p> Signup and view all the answers

What is important for managing proteinuria and its complications in glomerular disease?

<p>Sodium restriction</p> Signup and view all the answers

Which of the following is a negative prognostic indicator for glomerular disease in dogs?

<p>Hypertension</p> Signup and view all the answers

What is the most appropriate drug to prescribe for a 12-year-old male neutered Cocker Spaniel found to be proteinuric (UPC 3.2) and hypertensive (BP 170 mmHg) on routine geriatric panel?

<p>Amlodipine</p> Signup and view all the answers

What are the mild diuretics mentioned in the text for managing fluid accumulation?

<p>Hydrochlorothiazide</p> Signup and view all the answers

Which factor Xa inhibitor is mentioned in the text for the management of hypercoagulability?

<p>Rivaroxaban</p> Signup and view all the answers

What is the recommended monitoring interval for primary glomerulopathies initially?

<p>Every 2-4 weeks</p> Signup and view all the answers

Which drug is mentioned in the text as an immunosuppressive protocol for glomerulopathies?

<p>Mycophenolate mofetil</p> Signup and view all the answers

What is the most common cause of pyelonephritis?

<p>E. coli</p> Signup and view all the answers

Which antiplatelet drug is generally used in the management of hypercoagulability?

<p>Clopidogrel</p> Signup and view all the answers

What is the hallmark of glomerular disease?

<p>Proteinuria</p> Signup and view all the answers

What is the screening test for proteinuria in diagnosing glomerular disease?

<p>Urine protein:creatinine ratio (UPC)</p> Signup and view all the answers

What is the most common complication of glomerular disease?

<p>Thromboembolism</p> Signup and view all the answers

Which medication helps reduce proteinuria by inhibiting AngII production and blocking its receptor?

<p>Angiotensin Receptor Blockers (ARBs)</p> Signup and view all the answers

What is the essential diagnostic test for distinguishing between primary glomerular diseases?

<p>Renal biopsy</p> Signup and view all the answers

What is crucial for reducing intraglomerular pressures and magnitude of proteinuria?

<p>RAAS blockade</p> Signup and view all the answers

What is an adverse effect of Angiotensin Converting Enzyme Inhibitors (ACEi) and Angiotensin Receptor Blockers (ARBs)?

<p>Hyperkalemia</p> Signup and view all the answers

What is important for confirming proteinuria and identifying non-renal causes of hypertension?

<p>Serial monitoring</p> Signup and view all the answers

What is more common in middle-aged to older dogs with breed predispositions and a poorer prognosis?

<p>Protein-losing nephropathy (PLN)</p> Signup and view all the answers

What is a characteristic of protein-losing nephropathy (PLN)?

<p>Hypoalbuminemia</p> Signup and view all the answers

What is crucial for successful management of glomerular disease?

<p>Protein restriction</p> Signup and view all the answers

What is the mild antihypertensive mentioned in the text for managing hypertension in glomerular disease?

<p>Calcium channel blockers</p> Signup and view all the answers

Which type of proteinuria results from diseases affecting the proximal tubules?

<p>Renal proteinuria</p> Signup and view all the answers

What is the most common type of glomerular disease, causing damage to the glomerular filtration apparatus?

<p>Immune-complex glomerulonephritis (ICGN)</p> Signup and view all the answers

What can be the consequence of untreated glomerular diseases?

<p>Hypertension</p> Signup and view all the answers

What is the cause of glomerular (renal) proteinuria?

<p>Abnormal filtration by the glomerulus</p> Signup and view all the answers

What are the potential complications of glomerular diseases?

<p>Hypertension, hypercoagulability, and fluid accumulation</p> Signup and view all the answers

What is the most common cause of glomerular (renal) proteinuria?

<p>Abnormal filtration by the glomerulus</p> Signup and view all the answers

What type of glomerular disease is due to abnormal filtration by the glomerulus?

<p>Immune-complex glomerulonephritis (ICGN)</p> Signup and view all the answers

Which factor Xa inhibitor is mentioned in the text for the management of hypercoagulability?

<p>Rivaroxaban</p> Signup and view all the answers

What are the types of glomerular diseases?

<p>Functional and structural</p> Signup and view all the answers

What is the appropriate initial treatment time for reinfection of bacterial cystitis?

<p>7 days</p> Signup and view all the answers

What should be considered before selecting a drug for multi-drug resistant organisms causing UTI?

<p>Urine culture and sensitivity results</p> Signup and view all the answers

In the treatment of underlying glomerular disease, how often should monitoring be conducted initially?

<p>Every 6 months</p> Signup and view all the answers

Study Notes

Proteinuria and Glomerular Disease Overview

  • Proteinuria defined as abnormal amount of protein in urine
  • Proteinuria can be pre-renal, renal, or post-renal
  • Pre-renal proteinuria results from excess plasma proteins exceeding resorption in proximal renal tubules
  • Renal proteinuria is caused by diseases affecting the proximal tubules
  • Glomerular (renal) proteinuria is due to abnormal filtration by the glomerulus
  • Glomerular diseases can be functional or structural, with functional changes possibly progressing to structural damage
  • Post-renal proteinuria results from inflammation below the collecting duct
  • Glomerular diseases cause damage to the glomerular filtration barrier
  • Immune-complex glomerulonephritis (ICGN) is the most common glomerular disease, causing damage to the glomerular filtration apparatus
  • Glomerulosclerosis, amyloidosis, and hereditary nephropathies are other types of glomerular diseases
  • Glomerular diseases can lead to complications such as hypertension, hypercoagulability, and fluid accumulation
  • Hypertension is a common complication of glomerular diseases and can lead to end-organ damage

Proteinuria and Glomerular Disease Overview

  • Proteinuria defined as abnormal amount of protein in urine
  • Proteinuria can be pre-renal, renal, or post-renal
  • Pre-renal proteinuria results from excess plasma proteins exceeding resorption in proximal renal tubules
  • Renal proteinuria is caused by diseases affecting the proximal tubules
  • Glomerular (renal) proteinuria is due to abnormal filtration by the glomerulus
  • Glomerular diseases can be functional or structural, with functional changes possibly progressing to structural damage
  • Post-renal proteinuria results from inflammation below the collecting duct
  • Glomerular diseases cause damage to the glomerular filtration barrier
  • Immune-complex glomerulonephritis (ICGN) is the most common glomerular disease, causing damage to the glomerular filtration apparatus
  • Glomerulosclerosis, amyloidosis, and hereditary nephropathies are other types of glomerular diseases
  • Glomerular diseases can lead to complications such as hypertension, hypercoagulability, and fluid accumulation
  • Hypertension is a common complication of glomerular diseases and can lead to end-organ damage

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