Podcast
Questions and Answers
What characteristic distinguishes teicoplanin from vancomycin?
What characteristic distinguishes teicoplanin from vancomycin?
- Steric shield formation
- Oxidative couplings
- Dimerisation
- Alkyl chain anchoring to the cell membrane (correct)
Which process does not contribute to the biosynthesis of vancomycin?
Which process does not contribute to the biosynthesis of vancomycin?
- Ester link formation (correct)
- Glycosidation
- Chlorination
- Hydroxylation
What leads to resistance in vancomycin due to mutation?
What leads to resistance in vancomycin due to mutation?
- Oxidative couplings in the hexapeptide
- Dimerisation of the molecule
- Replacement of D-alanine by D-lactate (correct)
- Formation of a steric shield
What distinguishes oritavancin from eremomycin?
What distinguishes oritavancin from eremomycin?
Which characteristic is not true for telavancin analogues?
Which characteristic is not true for telavancin analogues?
What distinguishes eremomycin from vancomycin?
What distinguishes eremomycin from vancomycin?
What is the mechanism of action of cycloserine in inhibiting bacterial cell wall synthesis?
What is the mechanism of action of cycloserine in inhibiting bacterial cell wall synthesis?
How does vancomycin inhibit bacterial cell wall synthesis?
How does vancomycin inhibit bacterial cell wall synthesis?
Which enzyme is inhibited by phosphomycine in the process of bacterial cell wall synthesis?
Which enzyme is inhibited by phosphomycine in the process of bacterial cell wall synthesis?
What is the role of bacitracin in inhibiting bacterial cell wall synthesis?
What is the role of bacitracin in inhibiting bacterial cell wall synthesis?
Which phase of bacterial cell wall synthesis does teicoplanin target for inhibition?
Which phase of bacterial cell wall synthesis does teicoplanin target for inhibition?
What is the mechanism by which cycloserine inhibits bacterial cell wall synthesis?
What is the mechanism by which cycloserine inhibits bacterial cell wall synthesis?
Flashcards
Teicoplanin vs. Vancomycin difference
Teicoplanin vs. Vancomycin difference
Teicoplanin differs from vancomycin due to an alkyl chain anchoring to the cell membrane.
Vancomycin biosynthesis step missing
Vancomycin biosynthesis step missing
Ester link formation is not part of vancomycin's biosynthesis process.
Vancomycin resistance mutation
Vancomycin resistance mutation
Resistance arises from replacing D-alanine with D-lactate in vancomycin.
Oritavancin vs. Eremomycin difference
Oritavancin vs. Eremomycin difference
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Telavancin analogue FALSE characteristic
Telavancin analogue FALSE characteristic
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Eremomycin vs. Vancomycin: Key difference
Eremomycin vs. Vancomycin: Key difference
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Cycloserine's cell wall inhibition mechanism
Cycloserine's cell wall inhibition mechanism
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Vancomycin's cell wall inhibition mechanism
Vancomycin's cell wall inhibition mechanism
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Phosphomycine inhibited enzyme
Phosphomycine inhibited enzyme
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Bacitracin's cell wall inhibition role
Bacitracin's cell wall inhibition role
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Teicoplanin's target phase in bacterial cell wall
Teicoplanin's target phase in bacterial cell wall
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Cycloserine's mechanism of action
Cycloserine's mechanism of action
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