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Bacterial Cell Wall Synthesis Inhibition Quiz

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Bacterial Cell Wall Synthesis Inhibition Quiz

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Questions and Answers

What characteristic distinguishes teicoplanin from vancomycin?

Steric shield formation

Oxidative couplings

Dimerisation

Alkyl chain anchoring to the cell membrane (correct)

Which process does not contribute to the biosynthesis of vancomycin?

Ester link formation (correct)

Glycosidation

Chlorination

Hydroxylation

What leads to resistance in vancomycin due to mutation?

Oxidative couplings in the hexapeptide

Dimerisation of the molecule

Replacement of D-alanine by D-lactate (correct)

Formation of a steric shield

What distinguishes oritavancin from eremomycin?

Presence of a hydrophobic tail Signup and view all the answers

Which characteristic is not true for telavancin analogues?

Derived from a flexible hexapeptide Signup and view all the answers

What distinguishes eremomycin from vancomycin?

Naturally occurring glycopeptide Signup and view all the answers

What is the mechanism of action of cycloserine in inhibiting bacterial cell wall synthesis?

Inhibition of phosphoenolpyruvate transferase Signup and view all the answers

How does vancomycin inhibit bacterial cell wall synthesis?

Inhibition of transeptidase Signup and view all the answers

Which enzyme is inhibited by phosphomycine in the process of bacterial cell wall synthesis?

Phosphoenolpyruvate transferase Signup and view all the answers

What is the role of bacitracin in inhibiting bacterial cell wall synthesis?

Inhibition of phosphatase Signup and view all the answers

Which phase of bacterial cell wall synthesis does teicoplanin target for inhibition?

II° phase: Inhibition of peptidoglycan synthetase Signup and view all the answers

What is the mechanism by which cycloserine inhibits bacterial cell wall synthesis?

Acts within the cytoplasm and inhibits L-alanine racemase and D-Ala-D-Ala ligase Signup and view all the answers