27 Questions
Which of the following is NOT a major role of microtubules in cells?
Regulating gene expression
Which of the following is NOT a role of actin microfilaments in cells?
Facilitating protein transport
The dynamic instability of microtubules, where they rapidly grow and shrink, is explained by which concept?
Treadmilling
Which of the following is a structural feature of microfilaments found in lamellipodia?
Branched filaments
Which of the following proteins is involved in promoting the growth of microtubules?
Growth promoting proteins
Which of the following statements about membrane organization is correct?
Spatial organization of rafts is determined by their association with the cytoskeleton.
Which of the following statements about membrane fluidity is correct?
Liquid disordered and liquid ordered states refer to the packing of phospholipids in the membrane.
Which of the following is NOT a primary function of membrane proteins?
Synthesizing lipids for the membrane bilayer.
Which of the following statements about the membrane bilayer is correct?
The lipid bilayer creates an impermeable barrier to the passive diffusion of most molecules.
Which of the following is NOT a component of the fluid mosaic model of the cell membrane?
Ribosomes
Which of the following processes involves the SNARE proteins in the membrane?
Exocytosis
Which of the following is a primary function of microtubules within cells?
Maintaining cell polarity and forming cilia and flagella
Which of the following statements about microfilaments is correct?
They are involved in cell motility, lamellipodia, and filopodia formation.
What is the primary function of intermediate filaments within cells?
Providing structural support and withstanding tensile forces
Which of the following statements about linker proteins is correct?
They connect microtubules to microfilaments and intermediate filaments.
Which of the following statements accurately describes the relationship between the different cytoskeletal components?
Microtubules provide compressive strength, microfilaments generate tension, and intermediate filaments are elastic and withstand tensile forces.
Which of the following statements about the composition of cytoskeletal components is correct?
All of the above statements are correct.
What is the primary function of microtubule-associated proteins (MAPs) such as Tau?
Facilitate the formation of long, stable microtubule bundles
Which of the following statements about actin filaments is correct?
They exhibit plus-end growth and are polarized structures
What is the role of the Arp2/3 complex in actin dynamics?
It promotes the nucleation of new branching growth along existing filaments
Which of the following Rho GTPases is associated with the formation of filopodia?
Cdc42
What is the primary function of intermediate filaments (IFs) in animal cells?
Provide structural support and bear tension in tissues
What is the primary role of stathmin/Op18 in regulating microtubule dynamics?
It binds to and sequesters tubulin heterodimers
Which of the following actin-binding proteins is responsible for crosslinking adjacent microfilaments that cross?
Filamin
What is the primary function of katanin in regulating microtubule dynamics?
It severs microtubules, leading to their disassembly
Which of the following statements about microtubule dynamics is correct?
Microtubules exhibit plus-end growth and minus-end anchoring to the MTOC
What is the primary function of thymosin β4 in regulating actin dynamics?
It binds and sequesters free G-actin monomers, limiting F-actin growth
Test your knowledge on the major elements of bacterial and eukaryotic cytoskeleton, including the role of tubulins in forming microtubules, microtubules in cell functions, and the structure of cytoskeletal microtubules. Explore concepts like treadmilling and the role of actin in forming microfilaments.
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