Podcast
Questions and Answers
What determines how a word is pronounced and what it means?
What determines how a word is pronounced and what it means?
What type of bond exists between A-U and G-C in RNA?
What type of bond exists between A-U and G-C in RNA?
What is the basis of formation of a stem structure in RNA?
What is the basis of formation of a stem structure in RNA?
What happens when there is no complementarity in RNA?
What happens when there is no complementarity in RNA?
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What is the maximum number of bonds that can form between G-C in RNA?
What is the maximum number of bonds that can form between G-C in RNA?
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What is the result of the attraction between complementary strands in RNA?
What is the result of the attraction between complementary strands in RNA?
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In discussing RNA or DNA, which direction do we always refer to, from the 5 prime to the 3 prime end?
In discussing RNA or DNA, which direction do we always refer to, from the 5 prime to the 3 prime end?
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Which group of organisms was mentioned to be more primitive compared to bacteria?
Which group of organisms was mentioned to be more primitive compared to bacteria?
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When describing a ribbon-like RNA molecule, which end is considered the left and which the right?
When describing a ribbon-like RNA molecule, which end is considered the left and which the right?
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Why does the Formose reaction not favor a pentose sugar ribose as opposed to favoring many different molecules?
Why does the Formose reaction not favor a pentose sugar ribose as opposed to favoring many different molecules?
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What tool is predominantly used for comparing different organisms and their relatedness?
What tool is predominantly used for comparing different organisms and their relatedness?
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What raises the question of selectivity in the significance of a pentose sugar like ribose?
What raises the question of selectivity in the significance of a pentose sugar like ribose?
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Which bacterial group prefers a very high temperature environment?
Which bacterial group prefers a very high temperature environment?
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Where does the selectivity arise from when considering a pentose sugar like ribose for RNA?
Where does the selectivity arise from when considering a pentose sugar like ribose for RNA?
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Where does the branch of interest lie when comparing archaea and bacteria?
Where does the branch of interest lie when comparing archaea and bacteria?
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What is the significance of understanding molecules formed by the Formose reaction for the context of RNA?
What is the significance of understanding molecules formed by the Formose reaction for the context of RNA?
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What type of RNA was specifically mentioned to be used for comparing different organisms in the text?
What type of RNA was specifically mentioned to be used for comparing different organisms in the text?
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What do high genetic similarities between Thermococcus and thermos suggest?
What do high genetic similarities between Thermococcus and thermos suggest?
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What does the 'D' stand for in 'beta D ribo furanose'?
What does the 'D' stand for in 'beta D ribo furanose'?
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Which type of sugars are predominantly found in living organisms?
Which type of sugars are predominantly found in living organisms?
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What is the property of chemical molecules like amino acids that can rotate the plane of polarization of light?
What is the property of chemical molecules like amino acids that can rotate the plane of polarization of light?
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Which of the following statements is true regarding purines like adenine and guanine?
Which of the following statements is true regarding purines like adenine and guanine?
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In the prebiotic world, why did only some molecules get recruited into RNA structure?
In the prebiotic world, why did only some molecules get recruited into RNA structure?
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Which group of molecules are mainly formed due to physical and thermal activities in the prebiotic world?
Which group of molecules are mainly formed due to physical and thermal activities in the prebiotic world?
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What is one of the major limitations of DNA mentioned in the text?
What is one of the major limitations of DNA mentioned in the text?
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Why is extreme stability of DNA a limitation in terms of catalysis?
Why is extreme stability of DNA a limitation in terms of catalysis?
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What are the implications of DNA's stability on its reactivity during catalysis?
What are the implications of DNA's stability on its reactivity during catalysis?
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Why is stability an obstacle for DNA to act as a catalyst according to the text?
Why is stability an obstacle for DNA to act as a catalyst according to the text?
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What is one key difference between DNA and RNA mentioned in the text?
What is one key difference between DNA and RNA mentioned in the text?
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What kind of evidence has not been demonstrated regarding DNA's catalytic abilities in laboratory conditions according to the text?
What kind of evidence has not been demonstrated regarding DNA's catalytic abilities in laboratory conditions according to the text?
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Study Notes
Limitations of DNA
- DNA is a good prospect for storing genetic information, but it has limitations
- DNA is less reactive and very stable, which makes it reasonably inactive for catalysis
- There is no experimental evidence showing that DNA can act as a catalyst, even in laboratory conditions
RNA as a Storage of Genetic Information
- The sequence of RNA can contain information and mean something specific
- The hydrogen bonding between A-U and G-C allows RNA to carry information
- A RNA strand can make a copy of itself by attracting another nucleotide and pairing with it
Template and Complementarity
- A RNA strand will always attract a complementary strand, forming a stem structure
- When there is no complementarity, the structure remains a loop
- Directionality is important in RNA and DNA, with the 5' end being the "left hand" and the 3' end being the "right hand"
Prebiotic Synthesis of Sugars
- The Formose reaction can form many molecules, but it doesn't favor the pentose sugar ribose
- There is selectivity in the choice of ribose as a pentose sugar, but the mechanism of this selectivity is unclear
Classification of Living Organisms
- Living organisms can be classified into two categories: prokaryotes and eukaryotes
- Prokaryotes are more primitive and thought to have evolved earlier than eukaryotes
- Bacteria can be classified into three groups: archaea, bacteria, and eucarya
RNA Phylogeny
- RNA phylogeny is used to compare the relatedness of different organisms
- Thermococcus and thermus have high genetic similarity, indicating a close evolutionary relationship
- Ribosomal RNA phylogeny can reveal information about the evolutionary history of organisms
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Description
Test your knowledge on the classification of bacteria into different groups, including archaea and prokaryotes. Understand the differences between prokaryotes and eukaryotes and their evolutionary timelines.
