10 Questions
What is the main function of Th cells in the immune response?
Activate B cells to produce antibodies
Which molecule is responsible for the signal from Th cells to B cells during class switching?
CD154
In what location are IgA antibodies mainly transported to by B cells upon activation?
Mucosal surfaces
Which process introduces point mutations in V region exons of B cells during RNA transcription?
Somatic hypermutation
What is the enzyme responsible for converting cytosine to uracil during somatic hypermutation?
Cytidine Deaminase
What is the main outcome of competition among B cells with different antigen receptors?
Diversity in the mutated forms of antigen receptors
Which cytokine can block the activation of IgA antibodies by IL-21 in B cells?
[IL-4]
What is the mechanism by which high affinity plasma and memory cells are selected during somatic hypermutation?
[APOPTOSIS] of low affinity B cells
Which factor contributes more significantly to affinity maturation between class switching and somatic hypermutation?
[Somatic hypermutation]
Why are memory B cells able to produce antibodies with higher affinity during the secondary response?
Due to affinity maturation through somatic hypermutation
Test your knowledge on the outcomes of B cell proliferation, including class switching and antibody production. Learn about the role of T helper cells in the activation process and the functions of plasma cells.
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