B Cell Proliferation Outcomes Quiz
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Questions and Answers

What is the main function of Th cells in the immune response?

  • Activate B cells to produce antibodies (correct)
  • Induce apoptosis in B cells
  • Recognize MHC I
  • Directly attack pathogens
  • Which molecule is responsible for the signal from Th cells to B cells during class switching?

  • IL-21
  • CD40
  • IgM
  • CD154 (correct)
  • In what location are IgA antibodies mainly transported to by B cells upon activation?

  • Bone marrow
  • Mucosal surfaces (correct)
  • Lymph nodes
  • Bloodstream
  • Which process introduces point mutations in V region exons of B cells during RNA transcription?

    <p>Somatic hypermutation</p> Signup and view all the answers

    What is the enzyme responsible for converting cytosine to uracil during somatic hypermutation?

    <p>Cytidine Deaminase</p> Signup and view all the answers

    What is the main outcome of competition among B cells with different antigen receptors?

    <p>Diversity in the mutated forms of antigen receptors</p> Signup and view all the answers

    Which cytokine can block the activation of IgA antibodies by IL-21 in B cells?

    <p>[IL-4]</p> Signup and view all the answers

    What is the mechanism by which high affinity plasma and memory cells are selected during somatic hypermutation?

    <p>[APOPTOSIS] of low affinity B cells</p> Signup and view all the answers

    Which factor contributes more significantly to affinity maturation between class switching and somatic hypermutation?

    <p>[Somatic hypermutation]</p> Signup and view all the answers

    Why are memory B cells able to produce antibodies with higher affinity during the secondary response?

    <p>Due to affinity maturation through somatic hypermutation</p> Signup and view all the answers

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