B Cell Development and Selection Quiz
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Questions and Answers

Which process is responsible for changing the specificity of the antigen receptor in immature B cells?

  • Positive selection
  • Apoptosis
  • Negative selection
  • Receptor editing (correct)

What type of antigens are mostly recognized by developing B cells in the bone marrow?

  • Self antigens (correct)
  • Ubiquitous antigens
  • Microbial antigens
  • Foreign antigens

Is the process of Ig gene recombination biased towards recognition of microbes?

  • Yes
  • Only in T cells
  • It depends on the antigen
  • No (correct)

Flashcards

B cell receptor editing

A process that changes the specificity of the antigen receptor in immature B cells.

Antigen specificity

The ability of an antigen receptor to recognize a particular unique antigen.

Immature B cells

B cells that have not yet completed development and have antigen receptors.

Self-antigens

Antigens of the body that are not recognized as harmful by the immune system.

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Developing B cells

B cells in the bone marrow, in the process of maturation.

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Bone marrow

The site where B cells mature.

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Ig gene recombination

The process of rearranging immunoglobulin genes to create unique antigen receptors.

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Microbes

Foreign organisms that can cause diseases.

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Antigen recognition

Process when the immune system detects an invader (antigen).

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Receptor bias

Preference towards recognition of a specific type of antigen.

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Study Notes

Which process is responsible for changing the specificity of the antigen receptor in immature B cells? What type of antigens are mostly recognized by developing B cells in the bone marrow? Is the process of Ig gene recombination biased towards recognition of microbes?

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Description

Quiz: Understanding B Cell Development and Selection Test your knowledge on B cell development and selection with this quiz! Explore how B cells are positively selected based on the expression of complete antigen receptors and learn about the role of negative selection in shaping the B cell repertoire. Find out more about the intriguing processes that occur during B cell maturation.

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