Podcast
Questions and Answers
What proportion of known Mendelian disorders are inherited as autosomal dominant traits?
What proportion of known Mendelian disorders are inherited as autosomal dominant traits?
- More than half (correct)
- Less than one quarter
- Exactly one quarter
- One third
What is the chance of a child inheriting the affected allele if one parent is heterozygous (D/d) and the other is homozygous for the normal allele (d/d)?
What is the chance of a child inheriting the affected allele if one parent is heterozygous (D/d) and the other is homozygous for the normal allele (d/d)?
- 75%
- 25%
- 50% (correct)
- 100%
What is the genotype of offspring of two affected individuals (D/d) 25% of the time?
What is the genotype of offspring of two affected individuals (D/d) 25% of the time?
- D/D (correct)
- D/d
- d/d
- d/D
What can limit the observation of individuals with a homozygous genotype for a dominant phenotype?
What can limit the observation of individuals with a homozygous genotype for a dominant phenotype?
How can X-linked disorders be classified?
How can X-linked disorders be classified?
What is the characteristic of X-linked recessive conditions?
What is the characteristic of X-linked recessive conditions?
What is the main feature of mitochondrial inherited diseases?
What is the main feature of mitochondrial inherited diseases?
What is pleiotropy in the context of mitochondrial disorders?
What is pleiotropy in the context of mitochondrial disorders?
What is the process by which the mitochondrial genome is inherited from mother to offspring?
What is the process by which the mitochondrial genome is inherited from mother to offspring?
What is homoplasmy and heteroplasmy in the context of mtDNA inheritance?
What is homoplasmy and heteroplasmy in the context of mtDNA inheritance?
What is the condition for autosomal recessive diseases to occur in an individual?
What is the condition for autosomal recessive diseases to occur in an individual?
What is the risk of transmitting autosomal recessive disorders when both parents are carriers?
What is the risk of transmitting autosomal recessive disorders when both parents are carriers?
What is the genotype of an individual who is a carrier of an autosomal recessive disorder?
What is the genotype of an individual who is a carrier of an autosomal recessive disorder?
What is the phenotype of an individual who is a carrier of an autosomal recessive disorder?
What is the phenotype of an individual who is a carrier of an autosomal recessive disorder?
What is the result when both parents have the same autosomal recessive disorder?
What is the result when both parents have the same autosomal recessive disorder?
What is the term for the expression of an individual's genotype as observable traits?
What is the term for the expression of an individual's genotype as observable traits?
What is the term for having identical alleles at a locus?
What is the term for having identical alleles at a locus?
What type of disorders are determined by alleles at a single locus and follow Mendelian inheritance patterns?
What type of disorders are determined by alleles at a single locus and follow Mendelian inheritance patterns?
What is the term for an individual who inherits two different mutant alleles of a gene, one from each parent?
What is the term for an individual who inherits two different mutant alleles of a gene, one from each parent?
What is unique about mitochondrial DNA genotypes in terms of terminology?
What is unique about mitochondrial DNA genotypes in terms of terminology?
