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What is the primary role of genetic susceptibility in autoimmune diseases?
What is the primary role of genetic susceptibility in autoimmune diseases?
- Suppressing T-cell mediated responses
- Developing cross-reacting epitopes with self-antigens
- Playing an important role in the development of autoimmune diseases (correct)
- Triggering infections and tissue injury
What is the term used to describe the phenomenon where the body responds to a microbial antigen and attacks self-tissues?
What is the term used to describe the phenomenon where the body responds to a microbial antigen and attacks self-tissues?
- Self-antigen recognition
- Molecular tolerance
- Molecular mimicry (correct)
- Autoimmune response
What is the result of the breakdown of self-tolerance in autoimmune disorders?
What is the result of the breakdown of self-tolerance in autoimmune disorders?
- Release of sequestered antigens
- Loss of one or more mechanisms of self-tolerance (correct)
- Triggering of molecular mimicry
- Development of genetic susceptibility
Which of the following is an example of an autoimmune disease triggered by molecular mimicry?
Which of the following is an example of an autoimmune disease triggered by molecular mimicry?
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What is the role of HLA loci in autoimmune diseases?
What is the role of HLA loci in autoimmune diseases?
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What is the term used to describe the display and recognition of self-antigens after tissue injury or infection?
What is the term used to describe the display and recognition of self-antigens after tissue injury or infection?
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