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Questions and Answers
Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
- Phospholipase A2 (correct)
- Prostaglandin
- Cyclooxygenase
- Lipoxygenase
Which pathway is responsible for the formation of leukotrienes?
Which pathway is responsible for the formation of leukotrienes?
- Phospholipids pathway
- Lipoxygenase pathway (correct)
- Prostacyclin pathway
- Cyclooxygenase (COX) pathway
Which isoform of the COX enzyme is responsible for basal production of eicosanoids?
Which isoform of the COX enzyme is responsible for basal production of eicosanoids?
- Lipoxygenase
- COX-2
- Phospholipase A2
- COX-1 (correct)
Which enzyme pathway is associated with asthma and anaphylactic shock?
Which enzyme pathway is associated with asthma and anaphylactic shock?
Which autacoid is also known as a local hormone?
Which autacoid is also known as a local hormone?
Which molecule is cleaved from membrane-bound phosphatidylcholine to form arachidonic acid (AA)?
Which molecule is cleaved from membrane-bound phosphatidylcholine to form arachidonic acid (AA)?
Which type of drug has been approved for therapeutic uses on the female reproductive system?
Which type of drug has been approved for therapeutic uses on the female reproductive system?
What is the primary effect of LTC4 and LTD4 on the cardiovascular system?
What is the primary effect of LTC4 and LTD4 on the cardiovascular system?
Which drug is used for the treatment of pulmonary hypertension?
Which drug is used for the treatment of pulmonary hypertension?
What is the primary effect of LTB4 in inflammation?
What is the primary effect of LTB4 in inflammation?
Which mediator is responsible for causing bronchoconstriction and increased mucus secretion in the airways?
Which mediator is responsible for causing bronchoconstriction and increased mucus secretion in the airways?
What is the primary characteristic of asthma?
What is the primary characteristic of asthma?
What triggers the early asthmatic response?
What triggers the early asthmatic response?
What enzyme pathway is targeted by COX2-selective inhibitors?
What enzyme pathway is targeted by COX2-selective inhibitors?
Which drug is used to inhibit leukotriene receptors for the treatment of asthma?
Which drug is used to inhibit leukotriene receptors for the treatment of asthma?
Which drug is used for the treatment of erectile dysfunction?
Which drug is used for the treatment of erectile dysfunction?
What is the primary function of autacoids in the body?
What is the primary function of autacoids in the body?
Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
Which isoform of the COX enzyme is inducible by cytokines and other inflammatory stimuli?
Which isoform of the COX enzyme is inducible by cytokines and other inflammatory stimuli?
Which pathway is responsible for the formation of leukotrienes?
Which pathway is responsible for the formation of leukotrienes?
Which autacoid is associated with causing bronchoconstriction and increased mucus secretion in the airways?
Which autacoid is associated with causing bronchoconstriction and increased mucus secretion in the airways?
What is the primary effect of thromboxane A2 (TXA2) in the body?
What is the primary effect of thromboxane A2 (TXA2) in the body?
What is the primary effect of LTB4 in inflammation?
What is the primary effect of LTB4 in inflammation?
What triggers the early asthmatic response?
What triggers the early asthmatic response?
Which drug is used for the treatment of pulmonary hypertension?
Which drug is used for the treatment of pulmonary hypertension?
What enzyme pathway is responsible for the formation of leukotrienes?
What enzyme pathway is responsible for the formation of leukotrienes?
Which drug is used to inhibit leukotriene receptors for the treatment of asthma?
Which drug is used to inhibit leukotriene receptors for the treatment of asthma?
What is the primary effect of LTC4 and LTD4 on the cardiovascular system?
What is the primary effect of LTC4 and LTD4 on the cardiovascular system?
Which type of drug has been approved for therapeutic uses on the female reproductive system?
Which type of drug has been approved for therapeutic uses on the female reproductive system?
Which drug is used for the treatment of erectile dysfunction?
Which drug is used for the treatment of erectile dysfunction?
What enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
What enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?
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