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Autacoid and Autacoid Antagonist Quiz
31 Questions
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Autacoid and Autacoid Antagonist Quiz

Created by
@FearlessComputerArt

Questions and Answers

Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?

  • Phospholipase A2 (correct)
  • Prostaglandin
  • Cyclooxygenase
  • Lipoxygenase

    • Which pathway is responsible for the formation of leukotrienes?

  • Phospholipids pathway
  • Lipoxygenase pathway (correct)
  • Prostacyclin pathway
  • Cyclooxygenase (COX) pathway

    • Which isoform of the COX enzyme is responsible for basal production of eicosanoids?

  • Lipoxygenase
  • COX-2
  • Phospholipase A2
  • COX-1 (correct)

    • Which enzyme pathway is associated with asthma and anaphylactic shock?

    <p>Lipoxygenase pathway</p> Signup and view all the answers

    Which autacoid is also known as a local hormone?

    <p>Prostaglandin</p> Signup and view all the answers

    Which molecule is cleaved from membrane-bound phosphatidylcholine to form arachidonic acid (AA)?

    <p>Phospholipase A2</p> Signup and view all the answers

    Which type of drug has been approved for therapeutic uses on the female reproductive system?

    <p>Facilitation of Labor</p> Signup and view all the answers

    What is the primary effect of LTC4 and LTD4 on the cardiovascular system?

    <p>Reduce myocardial contractility and coronary blood flow</p> Signup and view all the answers

    Which drug is used for the treatment of pulmonary hypertension?

    <p>COX2-selective inhibitor</p> Signup and view all the answers

    What is the primary effect of LTB4 in inflammation?

    <p>Adherence and activation of inflammatory cells</p> Signup and view all the answers

    Which mediator is responsible for causing bronchoconstriction and increased mucus secretion in the airways?

    <p>LTD4</p> Signup and view all the answers

    What is the primary characteristic of asthma?

    <p>Inflammation of the airway</p> Signup and view all the answers

    What triggers the early asthmatic response?

    <p>Release of leukotrienes</p> Signup and view all the answers

    What enzyme pathway is targeted by COX2-selective inhibitors?

    <p>Cyclooxygenase pathway</p> Signup and view all the answers

    Which drug is used to inhibit leukotriene receptors for the treatment of asthma?

    <p>Glucocorticoids</p> Signup and view all the answers

    Which drug is used for the treatment of erectile dysfunction?

    <p>Alprostadil</p> Signup and view all the answers

    What is the primary function of autacoids in the body?

    <p>Inducing vasodilation</p> Signup and view all the answers

    Which enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?

    <p>Phospholipase A2</p> Signup and view all the answers

    Which isoform of the COX enzyme is inducible by cytokines and other inflammatory stimuli?

    <p>COX-2</p> Signup and view all the answers

    Which pathway is responsible for the formation of leukotrienes?

    <p>Lipoxygenase pathway</p> Signup and view all the answers

    Which autacoid is associated with causing bronchoconstriction and increased mucus secretion in the airways?

    <p>Leukotrienes</p> Signup and view all the answers

    What is the primary effect of thromboxane A2 (TXA2) in the body?

    <p>Promoting blood clotting</p> Signup and view all the answers

    What is the primary effect of LTB4 in inflammation?

    <p>Promotes adherence and activation of inflammatory cells</p> Signup and view all the answers

    What triggers the early asthmatic response?

    <p>Binding of allergen with IgE on mast cell</p> Signup and view all the answers

    Which drug is used for the treatment of pulmonary hypertension?

    <p>Leukotrienes receptor inhibitor</p> Signup and view all the answers

    What enzyme pathway is responsible for the formation of leukotrienes?

    <p>Lipoxygenase pathway</p> Signup and view all the answers

    Which drug is used to inhibit leukotriene receptors for the treatment of asthma?

    <p>Leukotrienes receptor inhibitor</p> Signup and view all the answers

    What is the primary effect of LTC4 and LTD4 on the cardiovascular system?

    <p>Reduces myocardial contractility and coronary blood flow</p> Signup and view all the answers

    Which type of drug has been approved for therapeutic uses on the female reproductive system?

    <p>Abortion inducer</p> Signup and view all the answers

    Which drug is used for the treatment of erectile dysfunction?

    <p>Alprostadil</p> Signup and view all the answers

    What enzyme is responsible for the cleavage of arachidonic acid (AA) from membrane-bound phosphatidylcholine?

    <p>Phospholipase A2</p> Signup and view all the answers

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