Atomoxetine Flashcards
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Questions and Answers

What is the brand name of Atomoxetine?

  • Adderall
  • Concerta
  • Ritalin
  • Strattera (correct)
  • What class of medication is Atomoxetine?

    Selective norepinephrine reuptake inhibitor

    What conditions is Atomoxetine commonly prescribed for?

    ADHD and treatment of resistant depression

    What is the mechanism of action of Atomoxetine?

    <p>Boosts norepinephrine and may also increase dopamine in the prefrontal cortex.</p> Signup and view all the answers

    How long until Atomoxetine works? The onset of therapeutic actions in ADHD can be seen as early as the first day of dosing, therapeutic actions may continue to improve for ___ weeks.

    <p>8-12</p> Signup and view all the answers

    What symptoms does Atomoxetine target in ADHD?

    <p>Inattentiveness, motor hyperactivity, and impulsiveness.</p> Signup and view all the answers

    Match the following side effects of Atomoxetine:

    <p>Increased appetite = Common side effect Dry mouth = Common side effect Increased heart rate = Common side effect Dizziness = Common side effect Increased heart rate and hypertension = Life-threatening side effect Severe liver damage = Life-threatening side effect</p> Signup and view all the answers

    What are some life-threatening side effects of Atomoxetine?

    <p>Increased heart rate, hypertension, severe liver damage, hypomania, and rare activation of suicidal ideation and behavior.</p> Signup and view all the answers

    How should Atomoxetine be dosed for children less than 70kg?

    <p>0.5mg/kg/day after 7 days increase to 1.2mg/kg/day.</p> Signup and view all the answers

    What are common overdose symptoms of Atomoxetine?

    <p>Sedation, agitation, hyperactivity, abnormal behavior, GI symptoms.</p> Signup and view all the answers

    What drug interaction associated with Atomoxetine increases the risk of seizures?

    <p>Tramadol</p> Signup and view all the answers

    Which medications increase plasma concentrations of Atomoxetine?

    <p>Both A and B</p> Signup and view all the answers

    Atomoxetine should be used with caution in patients with urinary retention and cardiovascular disease.

    <p>True</p> Signup and view all the answers

    Study Notes

    Atomoxetine Overview

    • Brand name is Strattera.
    • Classified as a selective norepinephrine reuptake inhibitor (NRI).
    • Commonly prescribed for ADHD and treatment-resistant depression.

    Mechanism of Action

    • Increases norepinephrine neurotransmission.
    • May enhance dopamine levels in the prefrontal cortex.

    Efficacy Timeline

    • Therapeutic effects for ADHD may be observed as early as the first day of dosing.
    • Continuous improvement can occur over 8-12 weeks; if ineffective after 6-8 weeks, discontinue.

    Symptom Reduction

    • Targets symptoms of inattentiveness, motor hyperactivity, and impulsiveness.
    • Aims to improve functioning in social, academic, and occupational settings.

    Side Effects

    • Common side effects include increased appetite, dry mouth, insomnia, anxiety, and dizziness.
    • Other effects: abdominal pain, dyspepsia, sweating, and decreased appetite.

    Severe Side Effects

    • Life-threatening risks include increased heart rate, hypertension, severe liver damage, and potential suicidal ideation.

    Dosing Guidelines

    • For children under 70 kg: Initial dose of 0.5 mg/kg/day; may increase to 1.2 mg/kg/day after 7 days. Maximum is 1.4 mg/kg/day or 100 mg, whichever is lower.
    • For adults or children over 70 kg: Start with 4 mg/day; can increase to 80 mg/day after 7 days and up to 100 mg/day in 2-4 weeks.

    Overdose Symptoms

    • Symptoms of overdose include sedation, agitation, hyperactivity, and gastrointestinal issues.

    Drug Interactions

    • Tramadol may increase seizure risk when combined with antidepressants.
    • Plasma concentrations may be elevated with paroxetine and fluoxetine.

    Cautionary Use

    • Use with caution in patients with urinary retention, benign prostatic hyperplasia (BPH), cardiovascular disease (CVD), cerebrovascular disease, hypertension, or tachycardia.

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    Description

    Test your knowledge on Atomoxetine with these flashcards. Covering key terms like brand name, class, and mechanism of action, this quiz is perfect for students of pharmacology or those interested in ADHD treatments. Enhance your understanding of this medication and its uses.

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