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Questions and Answers
What is the temperature at sea level in the International Standard Atmosphere (ISA)?
What is the temperature at sea level in the International Standard Atmosphere (ISA)?
At what altitude is atmospheric pressure approximately ½ of mean sea level (MSL) pressure?
At what altitude is atmospheric pressure approximately ½ of mean sea level (MSL) pressure?
What happens to temperature as altitude increases according to the lapse rate?
What happens to temperature as altitude increases according to the lapse rate?
What is the approximate temperature at an altitude of 36,090 ft (11 km)?
What is the approximate temperature at an altitude of 36,090 ft (11 km)?
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Which gas constitutes the largest percentage of the Earth's atmosphere?
Which gas constitutes the largest percentage of the Earth's atmosphere?
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What is the transition altitude (TA) in aviation?
What is the transition altitude (TA) in aviation?
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What does FL290 represent in aviation terms?
What does FL290 represent in aviation terms?
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According to Boyle's Law, what happens to gas pressure when volume increases?
According to Boyle's Law, what happens to gas pressure when volume increases?
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Which of the following is NOT a risk factor for hypertension?
Which of the following is NOT a risk factor for hypertension?
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What is considered primary (essential) hypertension?
What is considered primary (essential) hypertension?
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Which of the following methods is recommended to reduce high blood pressure?
Which of the following methods is recommended to reduce high blood pressure?
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Which condition is NOT a result of hypertension?
Which condition is NOT a result of hypertension?
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Which of the following dietary changes can help in managing blood pressure?
Which of the following dietary changes can help in managing blood pressure?
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What is the correct definition of cardiac output?
What is the correct definition of cardiac output?
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Which of the following is a secondary cause of hypertension?
Which of the following is a secondary cause of hypertension?
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What can be a possible effect of excessive alcohol consumption on blood pressure?
What can be a possible effect of excessive alcohol consumption on blood pressure?
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What is the formula to calculate cardiac output (CO)?
What is the formula to calculate cardiac output (CO)?
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What is the average stroke volume (SV) for a 70 kg individual?
What is the average stroke volume (SV) for a 70 kg individual?
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Which of the following is NOT a common cause of coronary artery disease?
Which of the following is NOT a common cause of coronary artery disease?
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What is a common symptom of coronary artery disease?
What is a common symptom of coronary artery disease?
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How much blood does an average adult male have?
How much blood does an average adult male have?
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What is the mean temperature of human blood?
What is the mean temperature of human blood?
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Which risk factor is associated with both coronary artery disease and high blood pressure?
Which risk factor is associated with both coronary artery disease and high blood pressure?
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What blood characteristic contributes to its higher viscosity compared to water?
What blood characteristic contributes to its higher viscosity compared to water?
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What is one of the primary functions of hemoglobin in red blood cells?
What is one of the primary functions of hemoglobin in red blood cells?
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Which of the following is NOT a function of platelets?
Which of the following is NOT a function of platelets?
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Anemia can be reported in a blood test as low:
Anemia can be reported in a blood test as low:
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What can lead to insufficient oxygen carried in the blood?
What can lead to insufficient oxygen carried in the blood?
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How do platelets contribute to stopping bleeding?
How do platelets contribute to stopping bleeding?
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What is the arterial oxygen saturation range in the Indifferent Stage/Zone?
What is the arterial oxygen saturation range in the Indifferent Stage/Zone?
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At which altitude does the Compensatory Stage/Zone begin?
At which altitude does the Compensatory Stage/Zone begin?
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Which of the following symptoms occurs in the Disturbance Stage/Zone?
Which of the following symptoms occurs in the Disturbance Stage/Zone?
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What is a critical symptom of the Critical Stage/Zone?
What is a critical symptom of the Critical Stage/Zone?
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How does arterial oxygen saturation change in the Compensatory Stage/Zone?
How does arterial oxygen saturation change in the Compensatory Stage/Zone?
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Which altitude marks the end of the Disturbance Stage/Zone?
Which altitude marks the end of the Disturbance Stage/Zone?
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What physiological adaptation occurs in the Compensatory Stage/Zone to maintain homeostasis?
What physiological adaptation occurs in the Compensatory Stage/Zone to maintain homeostasis?
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What is one of the primary effects of hypoxia starting at around 12 000 ft?
What is one of the primary effects of hypoxia starting at around 12 000 ft?
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Study Notes
Human Performance and Limitation
- Human bodily functions can be affected by factors like altitude, pressure, temperature, acceleration and perception changes while in flight.
Atmosphere
- The International Standard Atmosphere (ISA) is a model that shows how Earth's atmosphere changes with altitude.
- The ISA at sea level has a temperature of +15°C, pressure of 1013.25 mbs (760 mm Hg), and density of 1225 g/m³.
Lapse Rate
- Temperature decreases with altitude, with a lapse rate of 1.98°C/1000 ft (6.5°/km) up to 36,090 ft (11 km).
- Above 36,090 ft, temperature remains constant at -56.5°C up to 65,617 ft (20 km).
Atmospheric Pressure
- Pressure decreases with altitude.
- At approximately 36,000 ft, pressure is ¼ of sea level pressure.
- At approximately 18,000 ft, pressure is ½ of sea level pressure.
- At approximately 8,000 ft, pressure is ¾ of sea level pressure.
Composition of the Atmosphere
- Earth's atmosphere is composed of:
- Oxygen (O2) 21%
- Nitrogen (N2) 78%
- Argon (Ar) 0.93%
- Carbon dioxide (CO2) 0.03%
- Rare gases 0.04%
- This composition remains relatively constant up to about 70,000 ft (21 km).
Altitude in Aviation
- Altitude refers to elevation above mean sea level (MSL).
- Height refers to the vertical distance of an aircraft above the airfield elevation.
- Transition Altitude (TA) is the altitude above sea level where aircraft switch from using local barometric altitudes to flight levels.
- Flight Level (FL) represents altitude in thousands of feet above a standard pressure datum of 1013.2 mb. For example, FL290 means the aircraft altimeter indicates 29,000 ft.
- Cabin altitude refers to the pressure maintained within the aircraft cabin.
Physical Gas Laws
- The text mentions key gas laws including Boyle's Law, Dalton's Law, Henry's Law, and the General Gas Law.
Hypertension (High Blood Pressure)
- It's a condition where blood pressure is consistently high.
- Primary (essential) hypertension has no identifiable cause.
- Secondary hypertension is caused by other medical conditions:
- Obstructive sleep apnea
- Kidney problems
- Adrenal gland tumors
- Thyroid problems
- Certain birth defects in blood vessels
- Medications (birth control pills, cold remedies, decongestants, pain relievers)
- Illegal drugs (cocaine, amphetamines)
Hypertension Risk Factors
- Age
- Race
- Family history
- Being overweight or obese
- Not being physically active
- Using tobacco
- Excessive salt intake
- Low potassium intake
- Drinking too much alcohol
- Stress
- Certain chronic conditions
- Pregnancy (sometimes)
Reducing High Blood Pressure
-
Lifestyle Modifications:
- Increase activity and exercise.
- Lose weight if overweight.
- Reduce sugar and refined carbohydrates intake.
- Increase potassium intake and decrease sodium intake.
- Limit processed food consumption.
- Stop smoking.
- Manage stress.
- Try meditation or yoga.
-
Other Strategies:
- Eat dark chocolate.
- Use medicinal herbs.
- Ensure restful sleep.
- Consume garlic or take garlic extract supplements.
- Eat healthy high-protein foods.
- Take BP-lowering supplements.
- Moderate alcohol consumption.
- Reduce caffeine intake.
- Consider prescription medication.
Cardiac Output
- Cardiac output (CO) is the amount of blood pumped by each ventricle per minute.
- Stroke volume (SV) is the amount of blood pumped by each ventricle per beat.
- Heart rate (HR) is the number of heart contractions per minute (beats per minute, bpm).
- Mean CO for a 70 kg person is 5.25 L/min, with a range of 5.0–5.5 L/min for an average person.
- CO is calculated as: CO = HR * SV
Major Factors Influencing Cardiac Output
- This section points to a resource (video) for more information on factors influencing cardiac output.
Coronary Artery Disease
- Occurs when blood vessels supplying the heart become diseased or damaged.
- Symptoms include:
- Chest pain (angina)
- Shortness of breath
- Heart attack
Coronary Artery Disease Causes
- Smoking
- High blood pressure
- High cholesterol
- Diabetes or insulin resistance
- Sedentary lifestyle
Coronary Artery Disease Risk Factors
- Age
- Diabetes
- Sex
- Overweight or obesity
- Family history
- Physical inactivity
- Smoking
- High stress
- High blood pressure
- Unhealthy diet
- High blood cholesterol levels
Other Coronary Artery Disease Risk Factors
- Sleep apnea
- High-sensitivity C-reactive protein (hs-CRP)
- High triglycerides
- Homocysteine
- Preeclampsia
- Alcohol use
- Autoimmune diseases
Facts About Blood
- Blood makes up approximately 8% of an adult's body weight.
- Females have about 4-5 liters of blood, while males have about 5-6 liters.
- Blood temperature is about 38 degrees Celsius.
- Blood pH is slightly basic, ranging from 7.35 to 7.45.
- Blood is 4.5-5.5 times more viscous than water.
- Arterial blood is brighter red due to higher oxygen levels.
- There's no artificial substitute for human blood.
Platelets (Trombocitai)
- Platelets have several functions:
- Secrete vasoconstrictors to constrict blood vessels during bleeding.
- Form temporary platelet plugs to stop bleeding.
- Secrete procoagulants to promote blood clotting.
- Dissolve blood clots when no longer needed.
- Digest and destroy bacteria.
- Attract neutrophils and monocytes to inflammation sites.
- Secrete growth factors to maintain blood vessel linings.
Platelet Function During Bleeding
- The text explains the steps involved in blood clotting:
- Vascular spasms: Constriction of blood vessels.
- Platelet plug formation: Formation of a temporary plug over the injured area.
- Blood clotting (coagulation): Formation of a stable clot.
Hemoglobin (Hemoglobinas)
- Hemoglobin is a metalloprotein found in red blood cells.
- Normal hemoglobin levels:
- Male adults: 13.8 – 17.2 g/dL
- Female adults (non-pregnant): 12.1 – 15.1 g/dL
Hemoglobin Functions
- Oxygen carrier
- Carbon dioxide carrier
- Gives blood its red color
- Maintains red blood cell shape
- Acts as a buffer
- Interacts with other ligands
- Degradation produces physiologically active catabolites
Insufficient Oxygen Carried
- Causes of insufficient oxygen carried include:
- Anemia: Low number of red blood cells or hemoglobin.
- Insufficient oxygen pressure in the air
- Lack of iron
Anemia (Mažakraujystė)
- Anemia is characterized by a low number of red blood cells.
- Diagnosed through low hemoglobin or hematocrit readings in a blood test.
Altitude and Hypoxia
- The text describes the four stages of hypoxic hypoxia at different altitudes:
1. The Indifferent Stage/Zone (GL - 10,000 ft)
- Arterial oxygen saturation: 98% to 87%
- Dark adaption is negatively impacted (can be affected as low as 5,000 ft).
- Visual sensitivity decreases by approximately 10%.
- Performance of new tasks may be impaired.
- Heart and breathing rates increase slightly.
2. The Compensatory Stage/Zone (10,000 ft - 15,000 ft)
- Arterial oxygen saturation: 87% to 80%
- Physiological responses compensate for hypoxia to maintain homeostasis.
- These responses include:
- Increased respiratory volume
- Increased cardiac output and blood pressure
- Hypoxia-induced CNS effects include:
- Drowsiness
- Decreased judgment and memory
- Difficulty in performing complex tasks
- Short-term memory loss (detectable from about 12,000 ft)
3. The Disturbance Stage/Zone (15,000 ft - 20,000 ft)
- Arterial oxygen saturation: 80% to 65%
- Physiological responses are no longer sufficient for adequate oxygenation.
- Symptoms:
- Euphoria
- Dizziness
- Sleepiness
- Headache
- Fatigue
- Intellectual impairment and slow thought processes
- Memory impairment
- Severely impaired motor performance
- Loss of judgment
- "Grey-out" and tunnelled vision
4. The Critical Stage/Zone (20,000 ft - 23,000 ft)
- Arterial oxygen saturation: 65% to 60%
- Mental performance deteriorates rapidly.
- Confusion and dizziness occur within minutes.
- Loss of consciousness and incapacitation occur with little warning.
Summary of Body Oxygen Requirement at Altitude
- Factors influencing the severity and susceptibility to hypoxic hypoxia:
- Altitude
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Description
Explore how altitude, pressure, and temperature affect human bodily functions during flight. This quiz covers topics like the International Standard Atmosphere and the lapse rate, providing essential knowledge for understanding aircraft operations and human limitations at various altitudes.