ATI Pharmacology Infection Flashcards
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Questions and Answers

A nurse is caring for a client who has streptococcal pharyngitis and an allergy to penicillin. Which of the following drugs can be safely administered to this client?

  • Cefotetan
  • Isoniazid
  • Azithromycin (correct)
  • Acyclovir

A nurse is administering cefotetan IV to a client with an intra-abdominal infection. Which action should the nurse take if the IV site is warm, edematous, and painful?

  • Notify the provider immediately
  • Stop the cefotetan infusion (correct)
  • Increase the infusion rate
  • Flush the IV line

A nurse is caring for a client who has a new prescription for aztreonam. Which finding should the nurse recognize as requiring cautious use?

  • Diabetes
  • Hypertension
  • Renal impairment (correct)
  • Pregnancy

Which instruction should be included when teaching a client who takes an oral contraceptive and is beginning rifampin therapy?

<p>Use additional/non-hormonal form of contraception (D)</p> Signup and view all the answers

A nurse should identify that which of the following drugs can cause a reaction similar to disulfiram if the client drinks alcohol while taking it?

<p>Metronidazole (B), Cefotetan (D)</p> Signup and view all the answers

Cautious use of acyclovir IV is essential if the client also has which condition?

<p>Dehydration (A)</p> Signup and view all the answers

A nurse identifies that a client who was treated with imipenem IV might be experiencing which adverse effect if they report mouth pain?

<p>Superinfection (B)</p> Signup and view all the answers

A nurse should clarify the use of gentamicin with the provider if the client is taking which drug?

<p>Ethacrynic acid (A)</p> Signup and view all the answers

What adverse effect should a nurse monitor for when administering oral erythromycin to a client with acute diphtheria?

<p>Cardiac dysrhythmias (B)</p> Signup and view all the answers

Concurrent use of warfarin and trimethoprim/sulfamethoxazole increases the client's risk for which condition?

<p>Bleeding (A)</p> Signup and view all the answers

What medication will likely be administered to a client with methicillin-resistant MRSA?

<p>Vancomycin (A)</p> Signup and view all the answers

A nurse should instruct a client beginning isoniazid to report which adverse effects?

<p>Jaundice, numbness of the hands, and dizziness (B)</p> Signup and view all the answers

Which drug should the provider prescribe to prevent resistance to rifampin in a client being treated for TB?

<p>Isoniazid (INH) (C)</p> Signup and view all the answers

What condition indicates cautious use of metronidazole?

<p>Seizure disorder (D)</p> Signup and view all the answers

What should a nurse monitor when caring for a client beginning gentamicin therapy?

<p>Urine output (B)</p> Signup and view all the answers

A patient taking nitrofurantoin should report which adverse effect?

<p>Cough (D)</p> Signup and view all the answers

A nurse suspects a client on tetracycline may be experiencing which condition due to severe blood-tinged diarrhea?

<p>Clostridium difficile-associated diarrhea (A)</p> Signup and view all the answers

What instruction should a nurse give to a client taking ciprofloxacin who reports dyspepsia?

<p>Take an antacid at least 2 hours after taking the drug (B)</p> Signup and view all the answers

Prior to administering amphotericin B IV, which drugs should be given to minimize adverse reactions?

<p>Acetaminophen and diphenhydramine (A)</p> Signup and view all the answers

A patient taking ciprofloxacin should report which adverse effect due to the risk of tendon injury?

<p>Tendon pain (C)</p> Signup and view all the answers

What instruction should be given to a client taking penicillin V who reports abdominal cramping with bloody diarrhea?

<p>Bring in a stool sample for testing.</p> Signup and view all the answers

What should a client taking amoxicillin report if they experience a rash and wheezing?

<p>Call emergency services immediately.</p> Signup and view all the answers

What adverse effect should a nurse instruct a client taking itraconazole to report?

<p>Swelling of hands or feet.</p> Signup and view all the answers

What classification of antibiotics should be expected to be prescribed for bacterial meningitis?

<p>Third gen cephalosporins (A)</p> Signup and view all the answers

Which lab value should a nurse monitor for a client receiving acyclovir for a herpes simplex infection?

<p>BUN</p> Signup and view all the answers

Flashcards

What is azithromycin used for?

Azithromycin is a safe alternative for patients allergic to penicillin, particularly for streptococcal pharyngitis. It is a macrolide antibiotic.

What should you do if the IV site is inflamed during cefotetan infusion?

If the IV site becomes warm, edematous, and painful during cefotetan infusion, stop the infusion immediately to prevent complications. This could indicate phlebitis.

Who needs careful monitoring when taking aztreonam?

Caution is needed when using aztreonam in patients with impaired kidney function. This is because the drug is excreted by the kidneys and may accumulate in the body leading to toxicity.

How does rifampin affect birth control pills?

Rifampin can reduce the effectiveness of oral contraceptives. It is crucial to advise patients on additional non-hormonal contraceptive methods.

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What happens when you mix cefotetan or metronidazole with alcohol?

Both cefotetan and metronidazole can cause a disulfiram-like reaction if alcohol is consumed while taking these medications. This reaction is characterized by nausea, vomiting, flushing, and headache.

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Who needs extra care with acyclovir?

Acyclovir, a drug used to treat viral infections, should be administered with caution in patients with dehydration. This is to avoid renal impairment, as acyclovir is excreted by the kidneys.

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What symptom might indicate superinfection after imipenem treatment?

Imipenem can sometimes cause superinfection, which is an infection by a new organism that wasn't present initially. This could manifest as mouth pain.

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What should you be mindful of when administering gentamicin?

Gentamicin should be used with caution alongside ethacrynic acid. This combination can increase the risk of nephrotoxicity (kidney damage).

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Why is cardiac monitoring important when taking oral erythromycin?

Oral erythromycin for diphtheria requires careful monitoring for cardiac dysrhythmias. This is because erythromycin can affect the heart's rhythm.

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What drug interaction can increase bleeding risk?

Concurrent use of warfarin and trimethoprim/sulfamethoxazole can increase the risk of bleeding. Always double-check prescriptions with the doctor.

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What is the go-to medication for MRSA infections?

Vancomycin is the drug of choice for treating infections caused by methicillin-resistant Staphylococcus aureus (MRSA). It is a powerful antibiotic against these resistant bacteria.

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What signs should you look for in patients taking isoniazid?

Isoniazid can cause jaundice (yellowing of the skin and eyes) and neurological symptoms, including numbness and dizziness. It's essential to monitor for these adverse effects.

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Why is isoniazid sometimes combined with rifampin?

Isoniazid is frequently prescribed alongside rifampin to prevent antibiotic resistance. This combination therapy is often used for tuberculosis treatment.

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Who needs special attention when taking metronidazole?

Metronidazole should be used cautiously in patients with a history of seizures. It can potentially lower the seizure threshold.

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Why is urine output monitoring important for gentamicin?

Regular urine output checks should be performed for patients taking gentamicin. This is crucial for identifying potential nephrotoxicity (kidney damage).

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What symptom should be reported by patients on nitrofurantoin?

Patients taking nitrofurantoin should report any cough. Persistent cough can indicate pulmonary issues related to the medication.

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What does bloody diarrhea suggest in tetracycline patients?

Blood-tinged diarrhea in patients taking tetracycline could indicate antibiotic-associated diarrhea (AAD), often caused by Clostridium difficile.

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What should be avoided when taking ciprofloxacin?

Antacids should be taken at least 2 hours after ciprofloxacin to avoid absorption issues. This optimizes the drug's effectiveness.

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What is typically given before amphotericin B?

Before administering amphotericin B, pre-medication with acetaminophen and diphenhydramine is essential. This helps minimize infusion-related reactions like fever and chills.

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What symptom is crucial to report while on ciprofloxacin?

Patients taking ciprofloxacin should report any tendon pain, as this could indicate tendinopathy, a potential adverse reaction to the medication.

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What should patients on penicillin V do if they have abdominal issues?

Patients taking penicillin V should bring stool samples for testing if they experience severe abdominal symptoms. This helps rule out complications like antibiotic-associated diarrhea.

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What symptoms indicate an allergic reaction to amoxicillin?

If a patient on amoxicillin develops a rash and wheezing, this could be an allergic reaction. Immediate action is necessary to prevent serious complications.

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What symptom should patients using itraconazole watch out for?

Patients taking itraconazole should report swelling in extremities. This could be an adverse effect of the medication.

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What class of antibiotics is commonly used for bacterial meningitis?

Third-generation cephalosporins are the mainstay of treatment for bacterial meningitis. They provide broad coverage against various bacteria, including some resistant strains.

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Study Notes

Antibiotic Therapy Highlights

  • Azithromycin: Safe alternative for clients allergic to penicillin, particularly for streptococcal pharyngitis.
  • Cefotetan Effects: If IV site is warm, edematous, and painful, immediately stop the infusion to prevent complications.
  • Aztreonam Caution: Renal impairment increases the need for cautious use of aztreonam in respiratory infections.
  • Rifampin Precautions: Rifampin reduces the efficacy of oral contraceptives; advise clients to use additional non-hormonal methods.

Adverse Reactions and Monitoring

  • Disulfiram-like Reaction: Cefotetan and Metronidazole can induce reactions if alcohol is consumed while taking the drugs.
  • Acyclovir Consideration: Dehydration necessitates cautious use of acyclovir for viral infections, to avoid renal impairment.
  • Imipenem Risk: Client may experience superinfection indicated by mouth pain after treatment for bacterial infections.
  • Gentamicin Interactions: Clarify use with Ethacrynic acid to prevent toxic effects.
  • Erythromycin Monitoring: Watch for cardiac dysrhythmias in clients taking oral erythromycin for diphtheria.

Drug Interactions and Effects

  • Warfarin and Trimethoprim/Sulfamethoxazole: Concurrent use can elevate bleeding risk; verify prescriptions with the provider.
  • MRSA Treatment: Expect Vancomycin for methicillin-resistant Staphylococcus aureus infections.
  • Isoniazid Considerations: For clients on isoniazid, monitor for jaundice and neurological symptoms like numbness and dizziness.
  • Rifampin Combination Therapy: Isoniazid is often prescribed alongside rifampin to prevent antibiotic resistance.

Cautions and Instructions

  • Metronidazole in Seizure Patients: Cautious use required for clients with a history of seizures.
  • Gentamicin Monitoring for Kidney Function: Regular urine output checks essential to identify potential nephrotoxicity.
  • Nitrofurantoin Adverse Effects: Clients should report cough, indicating potential pulmonary issues.
  • Clostridium difficile Risk: Blood-tinged diarrhea in clients on tetracycline suggests possible antibiotic-associated diarrhea.
  • Ciprofloxacin Instructions: Advise taking antacids at least 2 hours after ciprofloxacin to prevent absorption issues.

Fungal and Bacterial Infections Management

  • Amphotericin B Precautions: Pre-medicate with Acetaminophen and Diphenhydramine to minimize infusion-related reactions.
  • Ciprofloxacin and Tendon Pain: Report any tendon pain due to the risk of tendinopathy associated with ciprofloxacin.
  • Monitoring Abdominal Symptoms: Advise clients on penicillin V to bring stool samples for testing if experiencing severe abdominal symptoms.
  • Allergic Reactions to Amoxicillin: Immediate action is necessary for rash and wheezing while on amoxicillin.
  • Itraconazole Monitoring: Clients taking itraconazole should report swelling in extremities as a potential adverse reaction.

Antibiotics for Meningitis

  • Third Generation Cephalosporins: Expected antibiotic class for treating bacterial meningitis, providing broader coverage against resistant organisms.

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Description

Test your knowledge on pharmacology related to infections with these flashcards. This quiz covers critical concepts such as drug allergies and treatment options for various infections. Enhance your understanding and prepare for real-life nursing scenarios.

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