Podcast
Questions and Answers
What gives atherosclerotic plaques their characteristic yellow color?
What gives atherosclerotic plaques their characteristic yellow color?
Which pigment is most commonly associated with sun tanning?
Which pigment is most commonly associated with sun tanning?
What is the most common inhaled pigment that is phagocytosed by alveolar macrophages?
What is the most common inhaled pigment that is phagocytosed by alveolar macrophages?
In which cells can exogenous pigments like carbon accumulate?
In which cells can exogenous pigments like carbon accumulate?
Signup and view all the answers
What pigment acts as a screen against harmful ultraviolet radiation?
What pigment acts as a screen against harmful ultraviolet radiation?
Signup and view all the answers
What are the three categories of intracellular accumulations mentioned in the text?
What are the three categories of intracellular accumulations mentioned in the text?
Signup and view all the answers
Which of the following is not a pathway of abnormal intracellular accumulations according to the text?
Which of the following is not a pathway of abnormal intracellular accumulations according to the text?
Signup and view all the answers
Which condition is characterized by the accumulation of excess cholesterol within cells?
Which condition is characterized by the accumulation of excess cholesterol within cells?
Signup and view all the answers
What is a common example of an exogenous pigment mentioned in the text?
What is a common example of an exogenous pigment mentioned in the text?
Signup and view all the answers
Which term is defined as an abnormal accumulation of iron in tissues, particularly in organs like the liver?
Which term is defined as an abnormal accumulation of iron in tissues, particularly in organs like the liver?
Signup and view all the answers
What is the major storage form of iron that accumulates in tissues when there is an excess of iron?
What is the major storage form of iron that accumulates in tissues when there is an excess of iron?
Signup and view all the answers
Which pigment is known as the 'wear and tear' pigment, consisting of lipids and phospholipids complexed with proteins?
Which pigment is known as the 'wear and tear' pigment, consisting of lipids and phospholipids complexed with proteins?
Signup and view all the answers
Which type of iron accumulation leads to tissue damage, scarring, and organ dysfunction?
Which type of iron accumulation leads to tissue damage, scarring, and organ dysfunction?
Signup and view all the answers
Which pigment can be identified unambiguously by the Prussian blue histochemical reaction?
Which pigment can be identified unambiguously by the Prussian blue histochemical reaction?
Signup and view all the answers
What is the golden-yellow to brown granular pigment that is derived from hemoglobin and can accumulate in liver cells?
What is the golden-yellow to brown granular pigment that is derived from hemoglobin and can accumulate in liver cells?
Signup and view all the answers
What is the term used to describe lipofuscin when it imparts an appearance to the tissue that is called brown atrophy?
What is the term used to describe lipofuscin when it imparts an appearance to the tissue that is called brown atrophy?
Signup and view all the answers
What is the typical appearance of lipofuscin in tissue sections?
What is the typical appearance of lipofuscin in tissue sections?
Signup and view all the answers
Which of the following tissues is lipofuscin NOT commonly seen in?
Which of the following tissues is lipofuscin NOT commonly seen in?
Signup and view all the answers
What forms the abnormal deposition of calcium salts seen in pathologic calcification?
What forms the abnormal deposition of calcium salts seen in pathologic calcification?
Signup and view all the answers
In which condition does dystrophic calcification occur?
In which condition does dystrophic calcification occur?
Signup and view all the answers
What is the term used to describe the abnormal accumulation of triglycerides within parenchymal cells?
What is the term used to describe the abnormal accumulation of triglycerides within parenchymal cells?
Signup and view all the answers
Which of the following is a condition that may result in the accumulation of proteins within cells due to defects in folding and transport?
Which of the following is a condition that may result in the accumulation of proteins within cells due to defects in folding and transport?
Signup and view all the answers
In which of the following conditions does an abnormal exogenous substance accumulate because the cell lacks the enzymatic machinery to degrade it?
In which of the following conditions does an abnormal exogenous substance accumulate because the cell lacks the enzymatic machinery to degrade it?
Signup and view all the answers
Which of the following substances may accumulate due to an inherited defect in an enzyme responsible for its degradation?
Which of the following substances may accumulate due to an inherited defect in an enzyme responsible for its degradation?
Signup and view all the answers
What type of change involves abnormal accumulation of minerals like iron or carbon within cells?
What type of change involves abnormal accumulation of minerals like iron or carbon within cells?
Signup and view all the answers
What is the consequence of parathyroid hormone excess on serum calcium levels?
What is the consequence of parathyroid hormone excess on serum calcium levels?
Signup and view all the answers
Where does metastatic calcification primarily occur due to increased secretion of parathyroid hormone?
Where does metastatic calcification primarily occur due to increased secretion of parathyroid hormone?
Signup and view all the answers
Which condition is NOT a cause of metastatic calcification?
Which condition is NOT a cause of metastatic calcification?
Signup and view all the answers
In which disease is metastatic calcification associated with renal failure as a cause of secondary hyperparathyroidism?
In which disease is metastatic calcification associated with renal failure as a cause of secondary hyperparathyroidism?
Signup and view all the answers
What is the principle cause of metastatic calcification related to destruction of bone tissue?
What is the principle cause of metastatic calcification related to destruction of bone tissue?
Signup and view all the answers
What is the major cause of fatty liver?
What is the major cause of fatty liver?
Signup and view all the answers
How does protein malnutrition contribute to lipid accumulation in the liver?
How does protein malnutrition contribute to lipid accumulation in the liver?
Signup and view all the answers
Which organ is commonly affected by fatty change?
Which organ is commonly affected by fatty change?
Signup and view all the answers
What morphological changes are observed in a severe fatty liver?
What morphological changes are observed in a severe fatty liver?
Signup and view all the answers
What distinguishes lipid accumulations from water or glycogen accumulations in the liver?
What distinguishes lipid accumulations from water or glycogen accumulations in the liver?
Signup and view all the answers
Which condition is associated with cholesterol and cholesterol esters accumulation?
Which condition is associated with cholesterol and cholesterol esters accumulation?
Signup and view all the answers
How do exogenous pigments like carbon accumulate in cells?
How do exogenous pigments like carbon accumulate in cells?
Signup and view all the answers
What is the effect of hepatotoxins like alcohol on lipid accumulation in the liver?
What is the effect of hepatotoxins like alcohol on lipid accumulation in the liver?
Signup and view all the answers
What is the consequence of severe fatty change in the liver?
What is the consequence of severe fatty change in the liver?
Signup and view all the answers
What can disrupt the steps of uptake, catabolism, or secretion leading to lipid accumulation?
What can disrupt the steps of uptake, catabolism, or secretion leading to lipid accumulation?
Signup and view all the answers