Atenolol Pharmacokinetics Quiz

What should be done after three sublingual (SL) nitroglycerin doses, administered 5 minutes apart, for patients outside of the hospital?

Continue taking more SL nitroglycerin doses
Seek medical attention (correct)
Wait for 10 minutes before seeking medical attention
Take a break for 30 minutes before seeking medical attention

How often is replacement of the SL nitroglycerin container necessary to prevent deactivation due to exposure to light?

Once a year
Once every 2 years
Every 3 months
Every 6 months (correct)

What is the shelf life of an opened translingual spray of nitroglycerin?

6 months
1 year
2 to 3 years (correct)
5 years

What is the recommended timing for taking extended-release oral nitrate preparations post-MI if angina persists after revascularization?

Morning after a nitrate-free interval (B) Signup and view all the answers

Why should nurses use special tubing provided by the manufacturer for IV nitroglycerin preparations?

PVC tubing absorbs up to 80% of the nitroglycerin (D) Signup and view all the answers

What is the goal of medical management in the context of myocardial function and complications prevention?

Minimize myocardial damage, preserve myocardial function, prevent complications (D) Signup and view all the answers

What is the purpose of administering IV beta-adrenergic blockers over 2.5 minutes?

To relieve hypotensive effects (B) Signup and view all the answers

What is the role of angiotensin-converting enzyme (ACE) inhibitors in patients with anterior infarction or heart failure?

To reduce mortality after an MI (B) Signup and view all the answers

What is the effect of administering aspirin during an evolving MI?

It substantially reduces mortality (B) Signup and view all the answers

What is the purpose of administering clopidogrel and ticagrelor for patients with unstable angina and NSTEMI?

To decrease the incidence of cardiovascular death and nonfatal MI (D) Signup and view all the answers

What is the main objective of glycoprotein IIb/IIIa receptor antagonists administration?

To inhibit platelet aggregation before and during invasive heart procedures (D) Signup and view all the answers

Which medication is widely used as the prototype nitrate for the management and prevention of acute chest pain caused by myocardial ischemia?

Nitroglycerin (B) Signup and view all the answers

What is the half-life of nitroglycerin?

1 to 4 minutes (D) Signup and view all the answers

How is nitroglycerin excreted from the body?

Excretion in the urine (C) Signup and view all the answers

What is the primary function of the medications used in the treatment of acute coronary syndrome?

Reducing oxygen demand of the myocardium (B) Signup and view all the answers

What is the primary function of beta-adrenergic blockers in treating acute coronary syndrome?

Reducing oxygen demand of the myocardium (C) Signup and view all the answers

Which drug undergoes extensive first-pass metabolism in the liver?

Nitroglycerin (A) Signup and view all the answers

What is the duration of action for transdermal ointment?

7 hours (D) Signup and view all the answers

What is the main mechanism by which nitroglycerin relieves angina?

Venous dilation (D) Signup and view all the answers

What is the most common adverse effect of nitroglycerin?

Severe headache (A) Signup and view all the answers

When is the administration of SL nitroglycerin or translingual spray essential?

As soon as chest pain develops (B) Signup and view all the answers

What is the onset time for IV nitroglycerin?

1 to 3 minutes (A) Signup and view all the answers

In which route of administration does nitroglycerin undergo rapid metabolism in the liver?

(PO) tablets or capsules (sustained release) (B) Signup and view all the answers

What is the effect of IV atenolol?

Immediate onset of action and dose-dependent duration (D) Signup and view all the answers

In what conditions is atenolol useful?

Treatment of angina, hypertension, and prophylaxis and treatment of MI (D) Signup and view all the answers

What is the reason for caution in administering atenolol to patients?

Severe bradycardia, heart failure, or hypotension (B) Signup and view all the answers

What is a major cardiac adverse reaction related to beta-adrenergic blockers such as atenolol?

Heart failure and substantial negative chronotropy (B) Signup and view all the answers

What condition should nonselective beta-adrenergic blockers not be used in?

Variant angina (D) Signup and view all the answers

What is one of the nursing implications for preventing interactions with atenolol?

Increasing the risk of bradycardia (C) Signup and view all the answers

What is the purpose of giving thrombolytic agents following a STEMI?

To dissolve thrombi and reestablish blood flow (D) Signup and view all the answers

What is the main concern regarding the use of morphine in post-MI patients?

Interfering with platelet inhibition (D) Signup and view all the answers

How does heparin work in the body?

By inhibiting clotting factors and preventing thrombus formation (B) Signup and view all the answers