Asthma Medications Mechanism Quiz
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Questions and Answers

What is the mechanism of action of dexamethasone in the bronchial smooth muscle?

  • Activates alpha-1 adrenergic receptors
  • Blocks histamine receptors on mast cells
  • Activates beta-2 adrenergic receptors
  • Binds to glucocorticoid receptors to reduce inflammation and airway sensitivity (correct)
  • How does salbutamol act on the bronchial smooth muscle?

  • Activates beta-2 adrenergic receptors for relaxation and dilation of the bronchioles (correct)
  • Causes vasoconstriction of blood vessels
  • Stimulates bronchial smooth muscle dilation
  • Blocks histamine receptors on mast cells
  • What are the effects of epinephrine in anaphylaxis?

  • Stimulates vasoconstriction of blood vessels (correct)
  • Binds to glucocorticoid receptors to reduce inflammation
  • Blocks histamine receptors on mast cells
  • Stimulates bronchial smooth muscle dilation
  • What is the primary effect of diphenhydramine in the body?

    <p>Blocks histamine receptors on mast cells</p> Signup and view all the answers

    Which receptor does epinephrine primarily activate in asthma?

    <p>Beta-2 adrenergic receptor</p> Signup and view all the answers

    What is the primary effect of dexamethasone in the bronchial smooth muscle?

    <p>Binds to glucocorticoid receptors to reduce inflammation and airway sensitivity</p> Signup and view all the answers

    What is the primary effect of Alpha-1 adrenergic receptor stimulation by epinephrine during cardiac arrest?

    <p>Vasoconstriction of vasculature throughout the entire body</p> Signup and view all the answers

    Which effect does amiodarone have on Phase 0 of the cardiac myocyte action potential?

    <p>Inhibits opening of fast sodium channels, slowing the influx of sodium</p> Signup and view all the answers

    What is the primary risk associated with normal saline (NS) bolus administration during cardiac arrest?

    <p>Fluid overload due to increased volume with weakened vasculature</p> Signup and view all the answers

    Where does dopamine primarily bind to D1 and D2 receptors?

    <p>CNS/cerebral cortex and PNS</p> Signup and view all the answers

    What is the effect of low dose dopamine administration?

    <p>Vasodilation and increased blood flow to renal and GI systems</p> Signup and view all the answers

    What is the primary effect of moderate dose dopamine administration?

    <p>Conversion to norepinephrine primarily acting on Beta-1 Adrenergic receptors</p> Signup and view all the answers

    What does high dose dopamine administration primarily lead to?

    <p>Increased resistance and blood pressure in the systemic vasculature</p> Signup and view all the answers

    What is the primary effect of Beta-2 adrenergic receptor stimulation by epinephrine during cardiac arrest?

    <p>Stimulation of bronchial smooth muscle dilation</p> Signup and view all the answers

    What is the primary effect of Beta-1 adrenergic receptor stimulation by epinephrine during cardiac arrest?

    <p>Increase in cardiac contractility and rate</p> Signup and view all the answers

    What is the primary effect of epinephrine on the vasculature during cardiac arrest?

    <p>Stimulates vasoconstriction of arteries, arterioles, and veins throughout the entire body</p> Signup and view all the answers

    What is the primary effect of amiodarone on Phase 0 of the cardiac myocyte action potential?

    <p>Inhibits opening of fast sodium channels, slowing the influx of sodium and conduction velocity</p> Signup and view all the answers

    What is the primary effect of normal saline (NS) bolus on the circulating volume during cardiac arrest?

    <p>Expands the circulating volume, assisting in 'priming the pump' and increasing preload</p> Signup and view all the answers

    What is the primary effect of dopamine at moderate doses on the cardiovascular system?

    <p>Converts to norepinephrine and acts on Beta-1 adrenergic receptors to increase cardiac contractility and rate</p> Signup and view all the answers

    What is the primary effect of epinephrine on the bronchial smooth muscle?

    <p>Stimulates dilation of bronchial smooth muscle and decreases airway resistance</p> Signup and view all the answers

    At high doses, what is the primary effect of dopamine on the systemic vasculature?

    <p>Increases resistance in systemic vasculature, leading to elevated blood pressure</p> Signup and view all the answers

    What is the primary effect of epinephrine on the heart during cardiac arrest?

    <p>Increases conduction through the SA node to stimulate increased chronotropy and inotropy</p> Signup and view all the answers

    What is the primary effect of normal saline (NS) bolus on body temperature during cardiac arrest?

    <p>May lead to hypothermia due to room temperature saline being lower than mean body temperature</p> Signup and view all the answers

    What is the primary effect of amiodarone on potassium channels during Phase 1/2/3 of the cardiac myocyte action potential?

    <p>Inhibits potassium channels, slowing potassium efflux during repolarization phase</p> Signup and view all the answers

    What is the primary effect of norepinephrine as a neurotransmitter in the cardiovascular system?

    <p>Acts as a neurotransmitter and adrenergic agonist in heart, vasculature, and kidneys</p> Signup and view all the answers

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