Arthritis in Dogs and Cats

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Questions and Answers

Which of the following is a medical device used in dogs for OA management?

Platelet rich plasma (PRP)

Radiosynoviorthesis (RSO) (correct)

Chondroitin sulfate

Autologous conditioned plasma (ACP)

Which NSAID is associated with PGE2 receptor (EP4) antagonist activity?

Firocoxib (correct)

Meloxicam

Etodolac

Tepoxalin

Which of the following is an example of a DMOAD (Disease Modifying Osteoarthritis Drug)?

Polysulfated glycosaminoglycan (Adequan®) (correct)

Galliprant

Robenacoxib

Meloxicam

Which of the following is a preventative measure for reducing OA causing diseases in the population?

Breeding strategies Signup and view all the answers

Which of the following is a side effect associated with Galliprant?

Immune mediate hemolytic anemia Signup and view all the answers

Which of the following is a source of adult multipotent stem cells for regenerative medicine in OA treatment?

Adipose tissue Signup and view all the answers

Which medication is currently not recommended as standard of care in OA treatment in people or animals?

Stem cell therapy Signup and view all the answers

Which of the following is a surgical option for OA that involves amputation?

Amputation Signup and view all the answers

Which of the following is a key characteristic of Osteoarthritis (OA)?

All of the Above Signup and view all the answers

Which of the following is the only supported drug for managing OA?

NSAIDs Signup and view all the answers

Which of the following best describes the definition of arthritis?

A broad term encompassing inflammatory disease processes within synovial joints Signup and view all the answers

What is the general etiology of osteoarthritis (OA)?

Aberrant repair and eventual degradation of articular cartilage in association with alternations in subchondral bone metabolism Signup and view all the answers

What are the diagnostic modalities for arthritic problems?

X-rays, MRI, and joint fluid analysis Signup and view all the answers

What are the medical management options for OA?

Nonsteroidal anti-inflammatory drugs (NSAIDs), physical therapy, and weight management Signup and view all the answers

What is the current understanding of the efficacy of medical management options available for treatment of OA?

They provide symptomatic relief and help improve joint function Signup and view all the answers

What is the role of surgical options in managing OA?

To address severe cases where conservative treatments have failed Signup and view all the answers

What are the primary classifications of arthritis?

Immune-mediated, primary, secondary, infective, hemarthrosis, crystal induced Signup and view all the answers

What are the secondary classifications of osteoarthritis (OA)?

Developmental disorders, joint instability, trauma Signup and view all the answers

Which of the following is true about the impact of OA?

It can lead to joint instability and functional impairment Signup and view all the answers

Which imaging modality is superior in quality and sensitivity for studying joint components and non-cartilaginous abnormalities?

MRI Signup and view all the answers

Which type of arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs?

Septic arthritis Signup and view all the answers

What is the underlying cause of crystal-induced arthritis reported in Dalmatians with hyperuricosuria?

Sodium urate crystal deposition Signup and view all the answers

Which joint is not commonly affected by osteoarthritis in dogs and cats?

Ankle Signup and view all the answers

What is the key factor in the etiology of osteoarthritis (OA) in dogs?

Genetics and Aging Signup and view all the answers

What is the pathogenesis of osteoarthritis (OA) involving, leading to pain and mobility impairment?

Cartilage loss, synovial inflammation, and osteophyte formation Signup and view all the answers

What type of arthritis can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA?

Immune-mediated polyarthritis Signup and view all the answers

What can result in hemarthrosis, the presence of blood in the joint?

Systemic coagulopathies Signup and view all the answers

Which imaging modality is the most common for diagnosing arthritis?

Radiography Signup and view all the answers

Study Notes

Arthritis in Dogs and Cats: Key Facts and Considerations

Osteoarthritis (OA) affects 20% of adult dogs, leading to impaired quality of life and associated costs.
Genetics and aging are key factors in the etiology of OA, with ongoing studies in canine models to identify candidate genes.
Body weight and obesity, exercise, and housing are environmental factors influencing OA development.
The pathogenesis of OA involves cartilage loss, synovial inflammation, and osteophyte formation, leading to pain and mobility impairment.
Common sites of OA in dogs and cats include the hip, elbow, stifle, and shoulder joints.
Immune-mediated polyarthritis (IMPA) can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA.
Septic arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs, and Pasteurella multicida and Bacteroides spp. in cats.
Hemarthrosis, the presence of blood in the joint, can result from trauma, systemic coagulopathies, or neoplastic conditions.
Crystal-induced arthritis, such as pseudo-gout and gout, is extremely rare in dogs, with sodium urate crystal deposition reported in Dalmatians with hyperuricosuria.
Diagnosis of arthritis involves clinical signs, diagnostic imaging (radiography, CT, MRI, ultrasound), and laboratory tests (hematology, serum biochemistry, urinalysis).
Radiography is the most common imaging modality, but MRI is superior in quality and sensitivity, particularly for studying joint components and non-cartilaginous abnormalities.
Laboratory tests, including serology for disease-specific markers and 4DX snap tests for Lyme disease, can aid in diagnosing arthritis and its underlying causes.

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Description

Test your knowledge about arthritis in dogs and cats with this informative quiz. Explore key facts, considerations, and underlying causes of osteoarthritis, immune-mediated polyarthritis, septic arthritis, and crystal-induced arthritis in canine and feline companions.