Podcast
Questions and Answers
Which of the following is a medical device used in dogs for OA management?
Which of the following is a medical device used in dogs for OA management?
- Platelet rich plasma (PRP)
- Radiosynoviorthesis (RSO) (correct)
- Chondroitin sulfate
- Autologous conditioned plasma (ACP)
Which NSAID is associated with PGE2 receptor (EP4) antagonist activity?
Which NSAID is associated with PGE2 receptor (EP4) antagonist activity?
- Firocoxib (correct)
- Meloxicam
- Etodolac
- Tepoxalin
Which of the following is an example of a DMOAD (Disease Modifying Osteoarthritis Drug)?
Which of the following is an example of a DMOAD (Disease Modifying Osteoarthritis Drug)?
- Polysulfated glycosaminoglycan (Adequan®) (correct)
- Galliprant
- Robenacoxib
- Meloxicam
Which of the following is a preventative measure for reducing OA causing diseases in the population?
Which of the following is a preventative measure for reducing OA causing diseases in the population?
Which of the following is a side effect associated with Galliprant?
Which of the following is a side effect associated with Galliprant?
Which of the following is a source of adult multipotent stem cells for regenerative medicine in OA treatment?
Which of the following is a source of adult multipotent stem cells for regenerative medicine in OA treatment?
Which medication is currently not recommended as standard of care in OA treatment in people or animals?
Which medication is currently not recommended as standard of care in OA treatment in people or animals?
Which of the following is a surgical option for OA that involves amputation?
Which of the following is a surgical option for OA that involves amputation?
Which of the following is a key characteristic of Osteoarthritis (OA)?
Which of the following is a key characteristic of Osteoarthritis (OA)?
Which of the following is the only supported drug for managing OA?
Which of the following is the only supported drug for managing OA?
Which of the following best describes the definition of arthritis?
Which of the following best describes the definition of arthritis?
What is the general etiology of osteoarthritis (OA)?
What is the general etiology of osteoarthritis (OA)?
What are the diagnostic modalities for arthritic problems?
What are the diagnostic modalities for arthritic problems?
What are the medical management options for OA?
What are the medical management options for OA?
What is the current understanding of the efficacy of medical management options available for treatment of OA?
What is the current understanding of the efficacy of medical management options available for treatment of OA?
What is the role of surgical options in managing OA?
What is the role of surgical options in managing OA?
What are the primary classifications of arthritis?
What are the primary classifications of arthritis?
What are the secondary classifications of osteoarthritis (OA)?
What are the secondary classifications of osteoarthritis (OA)?
Which of the following is true about the impact of OA?
Which of the following is true about the impact of OA?
Which imaging modality is superior in quality and sensitivity for studying joint components and non-cartilaginous abnormalities?
Which imaging modality is superior in quality and sensitivity for studying joint components and non-cartilaginous abnormalities?
Which type of arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs?
Which type of arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs?
What is the underlying cause of crystal-induced arthritis reported in Dalmatians with hyperuricosuria?
What is the underlying cause of crystal-induced arthritis reported in Dalmatians with hyperuricosuria?
Which joint is not commonly affected by osteoarthritis in dogs and cats?
Which joint is not commonly affected by osteoarthritis in dogs and cats?
What is the key factor in the etiology of osteoarthritis (OA) in dogs?
What is the key factor in the etiology of osteoarthritis (OA) in dogs?
What is the pathogenesis of osteoarthritis (OA) involving, leading to pain and mobility impairment?
What is the pathogenesis of osteoarthritis (OA) involving, leading to pain and mobility impairment?
What type of arthritis can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA?
What type of arthritis can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA?
What can result in hemarthrosis, the presence of blood in the joint?
What can result in hemarthrosis, the presence of blood in the joint?
Which imaging modality is the most common for diagnosing arthritis?
Which imaging modality is the most common for diagnosing arthritis?
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Study Notes
Arthritis in Dogs and Cats: Key Facts and Considerations
- Osteoarthritis (OA) affects 20% of adult dogs, leading to impaired quality of life and associated costs.
- Genetics and aging are key factors in the etiology of OA, with ongoing studies in canine models to identify candidate genes.
- Body weight and obesity, exercise, and housing are environmental factors influencing OA development.
- The pathogenesis of OA involves cartilage loss, synovial inflammation, and osteophyte formation, leading to pain and mobility impairment.
- Common sites of OA in dogs and cats include the hip, elbow, stifle, and shoulder joints.
- Immune-mediated polyarthritis (IMPA) can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA.
- Septic arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs, and Pasteurella multicida and Bacteroides spp. in cats.
- Hemarthrosis, the presence of blood in the joint, can result from trauma, systemic coagulopathies, or neoplastic conditions.
- Crystal-induced arthritis, such as pseudo-gout and gout, is extremely rare in dogs, with sodium urate crystal deposition reported in Dalmatians with hyperuricosuria.
- Diagnosis of arthritis involves clinical signs, diagnostic imaging (radiography, CT, MRI, ultrasound), and laboratory tests (hematology, serum biochemistry, urinalysis).
- Radiography is the most common imaging modality, but MRI is superior in quality and sensitivity, particularly for studying joint components and non-cartilaginous abnormalities.
- Laboratory tests, including serology for disease-specific markers and 4DX snap tests for Lyme disease, can aid in diagnosing arthritis and its underlying causes.
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