Arthritis in Dogs and Cats
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Questions and Answers

Which of the following is a medical device used in dogs for OA management?

  • Platelet rich plasma (PRP)
  • Radiosynoviorthesis (RSO) (correct)
  • Chondroitin sulfate
  • Autologous conditioned plasma (ACP)
  • Which NSAID is associated with PGE2 receptor (EP4) antagonist activity?

  • Firocoxib (correct)
  • Meloxicam
  • Etodolac
  • Tepoxalin
  • Which of the following is an example of a DMOAD (Disease Modifying Osteoarthritis Drug)?

  • Polysulfated glycosaminoglycan (Adequan®) (correct)
  • Galliprant
  • Robenacoxib
  • Meloxicam
  • Which of the following is a preventative measure for reducing OA causing diseases in the population?

    <p>Breeding strategies</p> Signup and view all the answers

    Which of the following is a side effect associated with Galliprant?

    <p>Immune mediate hemolytic anemia</p> Signup and view all the answers

    Which of the following is a source of adult multipotent stem cells for regenerative medicine in OA treatment?

    <p>Adipose tissue</p> Signup and view all the answers

    Which medication is currently not recommended as standard of care in OA treatment in people or animals?

    <p>Stem cell therapy</p> Signup and view all the answers

    Which of the following is a surgical option for OA that involves amputation?

    <p>Amputation</p> Signup and view all the answers

    Which of the following is a key characteristic of Osteoarthritis (OA)?

    <p>All of the Above</p> Signup and view all the answers

    Which of the following is the only supported drug for managing OA?

    <p>NSAIDs</p> Signup and view all the answers

    Which of the following best describes the definition of arthritis?

    <p>A broad term encompassing inflammatory disease processes within synovial joints</p> Signup and view all the answers

    What is the general etiology of osteoarthritis (OA)?

    <p>Aberrant repair and eventual degradation of articular cartilage in association with alternations in subchondral bone metabolism</p> Signup and view all the answers

    What are the diagnostic modalities for arthritic problems?

    <p>X-rays, MRI, and joint fluid analysis</p> Signup and view all the answers

    What are the medical management options for OA?

    <p>Nonsteroidal anti-inflammatory drugs (NSAIDs), physical therapy, and weight management</p> Signup and view all the answers

    What is the current understanding of the efficacy of medical management options available for treatment of OA?

    <p>They provide symptomatic relief and help improve joint function</p> Signup and view all the answers

    What is the role of surgical options in managing OA?

    <p>To address severe cases where conservative treatments have failed</p> Signup and view all the answers

    What are the primary classifications of arthritis?

    <p>Immune-mediated, primary, secondary, infective, hemarthrosis, crystal induced</p> Signup and view all the answers

    What are the secondary classifications of osteoarthritis (OA)?

    <p>Developmental disorders, joint instability, trauma</p> Signup and view all the answers

    Which of the following is true about the impact of OA?

    <p>It can lead to joint instability and functional impairment</p> Signup and view all the answers

    Which imaging modality is superior in quality and sensitivity for studying joint components and non-cartilaginous abnormalities?

    <p>MRI</p> Signup and view all the answers

    Which type of arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs?

    <p>Septic arthritis</p> Signup and view all the answers

    What is the underlying cause of crystal-induced arthritis reported in Dalmatians with hyperuricosuria?

    <p>Sodium urate crystal deposition</p> Signup and view all the answers

    Which joint is not commonly affected by osteoarthritis in dogs and cats?

    <p>Ankle</p> Signup and view all the answers

    What is the key factor in the etiology of osteoarthritis (OA) in dogs?

    <p>Genetics and Aging</p> Signup and view all the answers

    What is the pathogenesis of osteoarthritis (OA) involving, leading to pain and mobility impairment?

    <p>Cartilage loss, synovial inflammation, and osteophyte formation</p> Signup and view all the answers

    What type of arthritis can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA?

    <p>Immune-mediated polyarthritis</p> Signup and view all the answers

    What can result in hemarthrosis, the presence of blood in the joint?

    <p>Systemic coagulopathies</p> Signup and view all the answers

    Which imaging modality is the most common for diagnosing arthritis?

    <p>Radiography</p> Signup and view all the answers

    Study Notes

    Arthritis in Dogs and Cats: Key Facts and Considerations

    • Osteoarthritis (OA) affects 20% of adult dogs, leading to impaired quality of life and associated costs.
    • Genetics and aging are key factors in the etiology of OA, with ongoing studies in canine models to identify candidate genes.
    • Body weight and obesity, exercise, and housing are environmental factors influencing OA development.
    • The pathogenesis of OA involves cartilage loss, synovial inflammation, and osteophyte formation, leading to pain and mobility impairment.
    • Common sites of OA in dogs and cats include the hip, elbow, stifle, and shoulder joints.
    • Immune-mediated polyarthritis (IMPA) can be classified into non-erosive and erosive types, with various underlying causes such as systemic lupus erythematosus and breed-associated IMPA.
    • Septic arthritis can occur due to direct inoculation or hematogenous spread, with Staphylococcus and Streptococcus spp. commonly involved in dogs, and Pasteurella multicida and Bacteroides spp. in cats.
    • Hemarthrosis, the presence of blood in the joint, can result from trauma, systemic coagulopathies, or neoplastic conditions.
    • Crystal-induced arthritis, such as pseudo-gout and gout, is extremely rare in dogs, with sodium urate crystal deposition reported in Dalmatians with hyperuricosuria.
    • Diagnosis of arthritis involves clinical signs, diagnostic imaging (radiography, CT, MRI, ultrasound), and laboratory tests (hematology, serum biochemistry, urinalysis).
    • Radiography is the most common imaging modality, but MRI is superior in quality and sensitivity, particularly for studying joint components and non-cartilaginous abnormalities.
    • Laboratory tests, including serology for disease-specific markers and 4DX snap tests for Lyme disease, can aid in diagnosing arthritis and its underlying causes.

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    Description

    Test your knowledge about arthritis in dogs and cats with this informative quiz. Explore key facts, considerations, and underlying causes of osteoarthritis, immune-mediated polyarthritis, septic arthritis, and crystal-induced arthritis in canine and feline companions.

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