Questions and Answers
What is Aripiprazole (Abilify)?
What are some indications for using Aripiprazole (Abilify)?
Schizophrenia, acute mania, adjunct treatment of depression.
Which of the following is a common side effect of Aripiprazole (Abilify)?
Aripiprazole (Abilify) is contraindicated in patients with hypersensitivity.
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What is the drug action of Aripiprazole (Abilify)?
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What should be monitored when a patient is on Aripiprazole (Abilify)?
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Which condition requires caution when prescribing Aripiprazole (Abilify)?
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There is a risk of serotonin syndrome with concurrent use of SSRIs and Aripiprazole (Abilify).
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What is the drug classification of Aripiprazole (Abilify)?
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Study Notes
Aripiprazole (Abilify) Overview
- Aripiprazole is a third-generation antipsychotic classified as atypical.
- It is noted for causing manic reactions and akathisia.
- Unlike other antipsychotics, it has a lower likelihood of inducing weight gain or diabetes.
Drug Classification
- Classified as an antipsychotic and categorized as a dihydrocarbostyril.
- Available in both oral (PO) and intramuscular (IM) formulations.
Indications
- Primarily used to treat schizophrenia and acute mania.
- Also serves as adjunct therapy in managing depression.
Side Effects
- Common adverse effects include akathisia, confusion, depression, and drowsiness.
- Other potential side effects: fatigue, hostility, insomnia, lightheadedness, and nervousness.
- Serious risks include seizures, suicidal thoughts, tardive dyskinesia (TD), and neuroleptic malignant syndrome (NMS).
- Cardiovascular effects can range from lower to higher heart rate and blood pressure changes.
- Gastrointestinal issues: constipation, nausea, anorexia, and potential ulcers.
Nursing Responsibilities
- Monitor patients for signs of restlessness and fluctuations in weight.
- Aripiprazole is deemed least likely to cause diabetes among atypical antipsychotics.
Drug Action
- Functions as a dopamine and serotonin receptor agonist.
- Acts as an antagonist at the 5-HT2A receptor, indicating its modulatory role in neurotransmission.
Contraindications
- Administration is contraindicated in individuals with hypersensitivity to the drug.
Cautionary Measures
- Caution advised for patients with cardiovascular conditions, cerebrovascular issues, or hypotension.
- Liver enzyme inhibitors and medications that prolong the QT interval, such as SSRIs, warrant careful monitoring.
Drug Interactions
- Concomitant use with SSRIs increases the risk of serotonin syndrome, necessitating vigilance in prescribing practices.
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Description
This quiz consists of flashcards that cover essential information about Aripiprazole (Abilify), a third-generation antipsychotic. Key points include its drug classification, indications for use, and side effects. It's ideal for students and professionals in the field of psychiatry and pharmacology.
