Arenaviruses and Filoviruses Quiz

Which of the following is a characteristic of arenaviruses?

Which of the following is a characteristic of filoviruses?

What is the mode of transmission for arenaviruses?

What is the mode of transmission for filoviruses?

Which of the following is a virulence factor found in both filoviruses and arenaviruses?

Which virus is associated with lymphocytic choriomeningitis?

Which of the following is NOT a technique used to diagnose filovirus and arenavirus infections?

Which virus is responsible for causing Lassa fever?

How is Lassa fever primarily transmitted?

Which protein is responsible for viral cellular entry of arenaviruses?

What is the genomic composition of Lassa virus?

Which receptor does Ebola virus use to enter cells?

Which virus causes hemorrhagic fever and has a filamentous shape?

Which animal is the natural host of Lassa virus?

Which region is Lassa fever endemic to?

Characteristics of Viruses

Arenaviruses are characterized by being negative-sense RNA viruses
Filoviruses are characterized by being filamentous and containing a negative-sense RNA genome

Mode of Transmission

Arenaviruses are primarily transmitted through contact with infected rodents or their urine, feces, or saliva
Filoviruses are primarily transmitted through contact with infected bodily fluids, such as blood, sweat, and semen

Virulence Factors

The glycoprotein (GP) is a virulence factor found in both filoviruses and arenaviruses

Virus Associations

Lymphocytic choriomeningitis is associated with the LCMV virus, which is an arenavirus
Lassa fever is caused by the Lassa virus, which is an arenavirus
Ebola virus is a filovirus

Diagnosis

Immunofluorescence assay is a technique used to diagnose filovirus and arenavirus infections
Western blot is a technique used to diagnose filovirus and arenavirus infections
PCR (Polymerase Chain Reaction) is a technique used to diagnose filovirus and arenavirus infections
Gram staining is NOT a technique used to diagnose filovirus and arenavirus infections

Viral Entry and Genomics

The SSP (stable signal peptide) is responsible for viral cellular entry of arenaviruses
Lassa virus has a single-stranded negative-sense RNA genome
Ebola virus uses the receptor NPC1 (Niemann-Pick disease type C1) to enter cells

Lassa Fever

Lassa fever is primarily transmitted through contact with infected rodents or their urine, feces, or saliva
The Mastomys natalensis is the natural host of Lassa virus
Lassa fever is endemic to West Africa

Test your knowledge on the classification, structure, replication, and origins of arenaviruses and filoviruses. This quiz covers topics such as host reservoirs and modes of transmission. Challenge yourself to become an expert on these viral families.