Podcast
Questions and Answers
Apoptosis leads to cell shrinkage and increased density of cytoplasm.
Apoptosis leads to cell shrinkage and increased density of cytoplasm.
True
Tumors are resistant to apoptosis during their active growth phase.
Tumors are resistant to apoptosis during their active growth phase.
False
ER stress is the basis of degenerative diseases in the cardiovascular system.
ER stress is the basis of degenerative diseases in the cardiovascular system.
False
Viral infections like HIV and Hepatitis can lead to cell death through apoptosis.
Viral infections like HIV and Hepatitis can lead to cell death through apoptosis.
Signup and view all the answers
Apoptotic bodies are usually phagocytosed by neutrophils.
Apoptotic bodies are usually phagocytosed by neutrophils.
Signup and view all the answers
Radiation and cytotoxic drugs can cause DNA damage leading to apoptosis.
Radiation and cytotoxic drugs can cause DNA damage leading to apoptosis.
Signup and view all the answers
Apoptosis is a pathway of cell death that is induced by a tightly regulated suicide program.
Apoptosis is a pathway of cell death that is induced by a tightly regulated suicide program.
Signup and view all the answers
Necrosis and apoptosis have similar features.
Necrosis and apoptosis have similar features.
Signup and view all the answers
Apoptotic cells always elicit an inflammatory reaction.
Apoptotic cells always elicit an inflammatory reaction.
Signup and view all the answers
Apoptosis occurs only in pathologic conditions.
Apoptosis occurs only in pathologic conditions.
Signup and view all the answers
Hormone-dependent involution is an example of a physiologic cause of apoptosis.
Hormone-dependent involution is an example of a physiologic cause of apoptosis.
Signup and view all the answers
Apoptosis is a random process that occurs without any regulation.
Apoptosis is a random process that occurs without any regulation.
Signup and view all the answers
Necrosis is characterized by reduced cell size and intact plasma membrane.
Necrosis is characterized by reduced cell size and intact plasma membrane.
Signup and view all the answers
In apoptosis, cellular contents undergo enzymatic digestion and may leak out of the cell.
In apoptosis, cellular contents undergo enzymatic digestion and may leak out of the cell.
Signup and view all the answers
Apoptosis involves a reduction in cell size, brightly eosinophilic cytoplasm, and a condensed nucleus.
Apoptosis involves a reduction in cell size, brightly eosinophilic cytoplasm, and a condensed nucleus.
Signup and view all the answers
Necrosis is invariably a physiologic process.
Necrosis is invariably a physiologic process.
Signup and view all the answers
Protein cleavage in apoptosis is carried out by protease 'caspases'.
Protein cleavage in apoptosis is carried out by protease 'caspases'.
Signup and view all the answers
Apoptosis is a means of eliminating unwanted cells.
Apoptosis is a means of eliminating unwanted cells.
Signup and view all the answers
Apoptotic bodies are formed when cytoplasmic proteins swell and expand.
Apoptotic bodies are formed when cytoplasmic proteins swell and expand.
Signup and view all the answers
Signals from plasma membrane receptors in the death receptor pathway lead to the activation of executioner caspases.
Signals from plasma membrane receptors in the death receptor pathway lead to the activation of executioner caspases.
Signup and view all the answers
Apoptosis is also known as necrosis.
Apoptosis is also known as necrosis.
Signup and view all the answers
DNA breakdown in apoptosis is mainly mediated by exo-nucleases.
DNA breakdown in apoptosis is mainly mediated by exo-nucleases.
Signup and view all the answers
The two main pathways of apoptosis are the Death receptor Pathway and the Endoplasmic Reticulum Pathway.
The two main pathways of apoptosis are the Death receptor Pathway and the Endoplasmic Reticulum Pathway.
Signup and view all the answers
Imbalance in the BCL2 family of proteins can lead to leakage of pro-apoptotic substances from the nucleus.
Imbalance in the BCL2 family of proteins can lead to leakage of pro-apoptotic substances from the nucleus.
Signup and view all the answers