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Questions and Answers
Which organelle is primarily involved in the process of apoptosis in neurodegenerative disorders?
Which organelle is primarily involved in the process of apoptosis in neurodegenerative disorders?
- Cytoplasm
- Mitochondria (correct)
- Golgi complex
- Nucleus
What is the primary function of the CD95 cell marker?
What is the primary function of the CD95 cell marker?
- Necrosis of cell
- Extrinsic pathway of apoptosis (correct)
- Cellular hyperplasia
- Cellular adaptation
Which of the following characteristics is least likely to be observed in the neurons of a patient with Parkinson's disease?
Which of the following characteristics is least likely to be observed in the neurons of a patient with Parkinson's disease?
- Alteration in cellular membrane structure
- Cellular shrinkage
- Inflammation (correct)
- Nuclear fragmentation
Which statement about caspases is accurate?
Which statement about caspases is accurate?
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Which factor acts as an antiapoptotic agent?
Which factor acts as an antiapoptotic agent?
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Study Notes
Organelles Involved in Apoptosis
- Mitochondria are directly involved in the process of apoptosis, potentially contributing to the progression of neurodegenerative disorders.
- Cytoplasm, Golgi complex, and Nucleus are not directly involved in apoptosis.
Parkinson's Disease Neuron Features
- Nuclear fragmentation, cellular shrinkage, and alteration in cellular membrane structure are all seen in neurons of patients with Parkinson's disease.
- Inflammation is not necessarily seen in neurons of patients with Parkinson's disease.
CD95 Cell Marker
- CD95 is a cell marker involved in the extrinsic pathway of apoptosis, which is one of the two main pathways of programmed cell death.
Caspases
- Caspases are cysteine proteases, not alanine proteases.
- They exist as zymogens and undergo cleavage to become activated.
- Caspases are dependent on proapoptotic and antiapoptotic proteins.
- They are required for embryogenesis.
Anti-Apoptotic Factor
- BCL-2 is an antiapoptotic factor.
- BAX, p53, and Smac are all proapoptotic factors.
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