Apoptosis and Neurodegeneration Quiz

Which organelle is primarily involved in the process of apoptosis in neurodegenerative disorders?

What is the primary function of the CD95 cell marker?

Which of the following characteristics is least likely to be observed in the neurons of a patient with Parkinson's disease?

Which statement about caspases is accurate?

Which factor acts as an antiapoptotic agent?

Organelles Involved in Apoptosis

Mitochondria are directly involved in the process of apoptosis, potentially contributing to the progression of neurodegenerative disorders.
Cytoplasm, Golgi complex, and Nucleus are not directly involved in apoptosis.

Parkinson's Disease Neuron Features

Nuclear fragmentation, cellular shrinkage, and alteration in cellular membrane structure are all seen in neurons of patients with Parkinson's disease.
Inflammation is not necessarily seen in neurons of patients with Parkinson's disease.

CD95 Cell Marker

CD95 is a cell marker involved in the extrinsic pathway of apoptosis, which is one of the two main pathways of programmed cell death.

Caspases

Caspases are cysteine proteases, not alanine proteases.
They exist as zymogens and undergo cleavage to become activated.
Caspases are dependent on proapoptotic and antiapoptotic proteins.
They are required for embryogenesis.

Anti-Apoptotic Factor

BCL-2 is an antiapoptotic factor.
BAX, p53, and Smac are all proapoptotic factors.

Test your knowledge on the role of organelles in apoptosis, particularly in relation to neurodegenerative disorders like Parkinson's disease. Explore how cellular features and specific markers such as CD95 influence cell death pathways. Understand the function of caspases in the apoptosis process.