Aplastic Anemia Quiz

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Questions and Answers

What did Paul Ehrlich first describe in 1888?

  • Iron deficiency anemia
  • Hemolytic anemia
  • Sickle cell anemia
  • Aplastic anemia (correct)

What characterizes hypoproliferative disorders?

  • Reduced growth or production of blood cells (correct)
  • Abnormal shape of blood cells
  • Increased growth of blood cells
  • Excessive destruction of blood cells

What is the most common cause of acquired aplastic anemia?

  • Immune-mediated destruction of hematopoiesis (correct)
  • Viral infection
  • Genetic predisposition
  • Chemical exposure

What is the term for a congenital or genetic predisposition to bone marrow failure?

<p>Constitutional aplastic anemia (B)</p> Signup and view all the answers

Which agents are considered to cause iatrogenic aplastic anemia?

<p>Benzene and benze (B)</p> Signup and view all the answers

Which of the following is a characteristic of hypoproliferative disorders?

<p>Reduced growth of blood cells (C)</p> Signup and view all the answers

What is the most common cause of acquired aplastic anemia?

<p>Immune-mediated destruction of hematopoiesis (A)</p> Signup and view all the answers

What distinguishes idiopathic aplastic anemia?

<p>No established history of chemical or drug exposure or viral infection (A)</p> Signup and view all the answers

Which deficiency is not included in the anemias characterized by reduced growth or production of blood cells?

<p>Vitamin D (A)</p> Signup and view all the answers

What are the etiologic agents considered to cause iatrogenic aplastic anemia?

<p>Drug and chemical related agents (C)</p> Signup and view all the answers

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Study Notes

Historical Background

  • Paul Ehrlich first described aplastic anemia in 1888.

Hypoproliferative Disorders

  • Hypoproliferative disorders are characterized by a normal or decreased reticulocyte count.
  • Hypoproliferative disorders are accompanied by erythropoietic insufficiency.

Aplastic Anemia

  • The most common cause of acquired aplastic anemia is radiation and chemotherapy.
  • Idiopathic aplastic anemia is distinguished by the absence of a known cause.
  • Inherited bone marrow failure syndromes are a congenital or genetic predisposition to bone marrow failure, also known as Fanconi anemia.

Iatrogenic Aplastic Anemia

  • Chemotherapeutic agents, ionizing radiation, and benzene are considered to cause iatrogenic aplastic anemia.

Anemias

  • Vitamin B12 and folate deficiencies are included in the anemias characterized by reduced growth or production of blood cells.
  • Iron deficiency is not included in the anemias characterized by reduced growth or production of blood cells.

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