Podcast
Questions and Answers
Which of the following is a distinguishing feature of acquired aplastic anemia?
Which of the following is a distinguishing feature of acquired aplastic anemia?
- Onset in early childhood
- Presence of typical physical anomalies
- Abrupt onset of low blood counts in a previously well young adult (correct)
- Marrow hypocellularity after intensive cytotoxic chemotherapy for cancer
Which genetic disease usually presents in early childhood and has typical physical anomalies?
Which genetic disease usually presents in early childhood and has typical physical anomalies?
- RUNX1 mutation
- Dyskeratosis congenita
- Fanconi anemia (correct)
- GATA2 mutation
What can cause marrow hypocellularity in aplastic anemia?
What can cause marrow hypocellularity in aplastic anemia?
- Iatrogenic aplasia
- Radiation poisoning
- Chemotherapy for cancer (correct)
- Genetic diseases
Which of the following can present as marrow failure in normal-appearing adults?
Which of the following can present as marrow failure in normal-appearing adults?
What is a common manifestation of acquired aplastic anemia?
What is a common manifestation of acquired aplastic anemia?
Which of the following is a distinguishing feature of acquired aplastic anemia?
Which of the following is a distinguishing feature of acquired aplastic anemia?
What is a common manifestation of acquired aplastic anemia?
What is a common manifestation of acquired aplastic anemia?
What can cause marrow hypocellularity in aplastic anemia?
What can cause marrow hypocellularity in aplastic anemia?
Which genetic disease usually presents in early childhood and has typical physical anomalies?
Which genetic disease usually presents in early childhood and has typical physical anomalies?
Which of the following can present as marrow failure in normal-appearing adults?
Which of the following can present as marrow failure in normal-appearing adults?
Which of the following is a distinguishing feature of acquired aplastic anemia?
Which of the following is a distinguishing feature of acquired aplastic anemia?
Which genetic disease usually presents in early childhood and has typical physical anomalies?
Which genetic disease usually presents in early childhood and has typical physical anomalies?
What can cause marrow hypocellularity in aplastic anemia?
What can cause marrow hypocellularity in aplastic anemia?
Which of the following can present as marrow failure in normal-appearing adults?
Which of the following can present as marrow failure in normal-appearing adults?
What is a common manifestation of acquired aplastic anemia?
What is a common manifestation of acquired aplastic anemia?
What are the distinguishing features of acquired aplastic anemia?
What are the distinguishing features of acquired aplastic anemia?
What are some genetic diseases that can present as marrow failure in normal-appearing adults?
What are some genetic diseases that can present as marrow failure in normal-appearing adults?
What are some genetic diseases that usually present in early childhood and have typical physical anomalies?
What are some genetic diseases that usually present in early childhood and have typical physical anomalies?
What is pancytopenia?
What is pancytopenia?
What can cause bone marrow hypocellularity in aplastic anemia?
What can cause bone marrow hypocellularity in aplastic anemia?
Study Notes
Acquired Aplastic Anemia
- Distinguishing feature: marrow hypocellularity, which can be caused by radiation, chemotherapy, and toxins
- Common manifestation: pancytopenia, a condition characterized by a decrease in all three types of blood cells (red, white, and platelets)
Genetic Diseases
- Fanconi anemia: usually presents in early childhood, has typical physical anomalies, and can present as marrow failure in normal-appearing adults
- Dyskeratosis congenita: usually presents in early childhood, has typical physical anomalies, and can present as marrow failure in normal-appearing adults
Marrow Failure
- Can be caused by acquired aplastic anemia, which is a condition where the bone marrow fails to produce enough blood cells
- Can be caused by genetic diseases, such as Fanconi anemia and Dyskeratosis congenita, which usually present in early childhood and have typical physical anomalies
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Description
Test your knowledge on Aplastic Anemia and its various forms, including acquired and constitutional types. Learn about the causes, symptoms, and genetic diseases associated with this condition.