Anxiolytic Drugs Quiz

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Questions and Answers

Which receptor do anxiolytic drugs predominantly act on?

  • GABA receptors (correct)
  • Glutamate receptors
  • Dopamine receptors
  • Serotonin receptors

What is the main disadvantage of diazepam as a sedative and anxiolytic?

  • Devoid of emetic side effects
  • Predictable anxiolytic and sedative action
  • Long elimination half-life (correct)
  • Rapid absorption when given by mouth

Which benzodiazepine is recommended for oral premedication due to its rapid absorption and anxiolytic action similar to that of morphine?

  • Alprazolam
  • Lorazepam
  • Midazolam
  • Diazepam (correct)

Why is intramuscular injection of diazepam not recommended?

<p>It is painful (D)</p> Signup and view all the answers

What is the pharmacokinetic property that differs among benzodiazepines?

<p>Duration of action (D)</p> Signup and view all the answers

What makes midazolam a suitable agent for producing conscious sedation?

<p>Its negligible soporific effects (A)</p> Signup and view all the answers

Why are opioids usually the agents of choice in the presence of acute severe pain?

<p>They are usually the most potent analgesic drugs (D)</p> Signup and view all the answers

What is the primary reason for using NSAIDs in day surgery?

<p>To reduce the required dose of anesthetic agent (D)</p> Signup and view all the answers

What is the reason for preferring pethidine over morphine in some cases?

<p>It causes less histamine release (D)</p> Signup and view all the answers

What is the primary effect of clonidine given as a premedication?

<p>To reduce postoperative pain in children (B)</p> Signup and view all the answers

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Study Notes

Anxiolytic Drugs and Sedatives

  • Anxiolytic drugs predominantly act on the GABA receptor.
  • The main disadvantage of diazepam as a sedative and anxiolytic is its long duration of action, leading to prolonged sedation.

Benzodiazepines

  • Midazolam is recommended for oral premedication due to its rapid absorption and anxiolytic action similar to that of morphine.
  • Diazepam is not recommended for intramuscular injection due to its slow and irregular absorption from the muscle.
  • The pharmacokinetic property that differs among benzodiazepines is their half-life.

Conscious Sedation and Pain Management

  • Midazolam is a suitable agent for producing conscious sedation due to its short half-life, rapid onset, and offset of action.
  • Opioids are usually the agents of choice in the presence of acute severe pain due to their potent analgesic action.
  • The primary reason for using NSAIDs in day surgery is to provide postoperative pain relief.
  • Pethidine is preferred over morphine in some cases due to its shorter duration of action and less histamine release.

Premedication

  • The primary effect of clonidine given as a premedication is to produce sedation and anxiolysis.

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