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Anxiolytic Drugs: Mechanism and Effects
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Anxiolytic Drugs: Mechanism and Effects

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Questions and Answers

Which receptor do anxiolytic drugs predominantly act on?

  • Serotonin receptors
  • Glutamate receptors
  • GABA receptors (correct)
  • Dopamine receptors
  • What is the main disadvantage of diazepam as a sedative and anxiolytic?

  • Lack of amnesic properties
  • Short elimination half-life
  • Prolonged duration of action (correct)
  • Predictable anxiolytic and sedative action
  • What property of midazolam makes it suitable for conscious sedation in short endoscopic procedures and pre-operative sedation?

  • Water solubility
  • Lipid solubility (correct)
  • Long elimination half-life
  • Presence of soporific metabolites
  • Which benzodiazepine is rapidly absorbed when given by mouth and exerts an anxiolytic action similar to that of morphine?

    <p>Diazepam</p> Signup and view all the answers

    Which benzodiazepine is a water-soluble derivative and becomes highly lipid soluble at physiologic pH?

    <p>Midazolam</p> Signup and view all the answers

    Which drug has been found to provide pre-operative sedative effect superior to that of diazepam?

    <p>Midazolam</p> Signup and view all the answers

    Which classification of opioids includes drugs like morphine and codeine?

    <p>Natural Opium Alkaloids</p> Signup and view all the answers

    Which drug has been shown to reduce postoperative pain in children?

    <p>Clonidine</p> Signup and view all the answers

    What is the effect of benzodiazepines on the respiratory system?

    <p>No effect</p> Signup and view all the answers

    Which opioid is 1/10th as potent as morphine but has similar efficacy, sedation, euphoria, and respiratory depression in equianalgesic dose?

    <p>Pethidine</p> Signup and view all the answers

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