Anxiolytic Drugs: Mechanism and Effects

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Questions and Answers

Which receptor do anxiolytic drugs predominantly act on?

  • Serotonin receptors
  • Glutamate receptors
  • GABA receptors (correct)
  • Dopamine receptors

What is the main disadvantage of diazepam as a sedative and anxiolytic?

  • Lack of amnesic properties
  • Short elimination half-life
  • Prolonged duration of action (correct)
  • Predictable anxiolytic and sedative action

What property of midazolam makes it suitable for conscious sedation in short endoscopic procedures and pre-operative sedation?

  • Water solubility
  • Lipid solubility (correct)
  • Long elimination half-life
  • Presence of soporific metabolites

Which benzodiazepine is rapidly absorbed when given by mouth and exerts an anxiolytic action similar to that of morphine?

<p>Diazepam (A)</p> Signup and view all the answers

Which benzodiazepine is a water-soluble derivative and becomes highly lipid soluble at physiologic pH?

<p>Midazolam (C)</p> Signup and view all the answers

Which drug has been found to provide pre-operative sedative effect superior to that of diazepam?

<p>Midazolam (D)</p> Signup and view all the answers

Which classification of opioids includes drugs like morphine and codeine?

<p>Natural Opium Alkaloids (B)</p> Signup and view all the answers

Which drug has been shown to reduce postoperative pain in children?

<p>Clonidine (B)</p> Signup and view all the answers

What is the effect of benzodiazepines on the respiratory system?

<p>No effect (A)</p> Signup and view all the answers

Which opioid is 1/10th as potent as morphine but has similar efficacy, sedation, euphoria, and respiratory depression in equianalgesic dose?

<p>Pethidine (B)</p> Signup and view all the answers

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