Antitussives and Expectorants in Pharmacology
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Questions and Answers

Bromhexine is an example of a bronchodilator.

False

Mometasone is a type of mucolytic drug.

False

Acetylcysteine is used to relieve bronchospasms.

False

Salbutamol is a long-acting β-receptor agonist.

<p>False</p> Signup and view all the answers

Xanthine derivatives are used to dilate airways and increase airflow.

<p>True</p> Signup and view all the answers

Leukotriene antagonists are used to treat COPD.

<p>True</p> Signup and view all the answers

Ambroxol is a type of corticosteroid.

<p>False</p> Signup and view all the answers

Corticosteroids are used to relieve bronchospasms.

<p>False</p> Signup and view all the answers

Dextromethorphan is a non-opioid expectorant.

<p>False</p> Signup and view all the answers

Antihistamines are used to relieve cold symptoms, such as sneezing and runny nose.

<p>True</p> Signup and view all the answers

Guaifenesin is a type of antitussive.

<p>False</p> Signup and view all the answers

Phenylephrine is a type of decongestant that reduces congestion of nasal passages and increases drainage of sinuses.

<p>True</p> Signup and view all the answers

Codeine is an opioid antitussive that is commonly used in children.

<p>False</p> Signup and view all the answers

Loratadine is a type of decongestant.

<p>False</p> Signup and view all the answers

Expectorants are used to relieve productive coughs.

<p>False</p> Signup and view all the answers

Oxymetazoline is a type of antihistamine.

<p>False</p> Signup and view all the answers

Antitussive drugs are used to treat productive cough and help clear the airway.

<p>False</p> Signup and view all the answers

Mucolytics are drugs used to reduce nasal congestion.

<p>False</p> Signup and view all the answers

Expectorants are used to stop or reduce coughing.

<p>False</p> Signup and view all the answers

Decongestants are used to treat viral infections.

<p>False</p> Signup and view all the answers

Antihistamines are used to treat allergic reactions.

<p>True</p> Signup and view all the answers

Cough suppressants are used to treat productive cough.

<p>False</p> Signup and view all the answers

Non-productive cough is associated with bacterial infections.

<p>False</p> Signup and view all the answers

Mucolytics are used to treat lower respiratory tract disorders.

<p>True</p> Signup and view all the answers

Study Notes

Upper Respiratory Tract Disorders

  • Inflammatory disorders: rhinitis, sinusitis, tonsillitis, and common cold
  • Viral or bacterial infections cause excessive mucus production and irritation of nasal mucosa
  • Symptoms: sneeze and cough reflex, nasal congestion, and mucosal irritation

Cough Physiology

  • Cough is a physiological and protective reflex to clear airways
  • Can be a sign of disease, such as infections, asthma, or pulmonary tumors
  • Two types of cough:
    • Non-productive cough: viral infection, dry cough, no excessive mucus production, can be treated with cough suppressants
    • Productive cough: bacterial infections, excessive mucus production, coughing helps clear airways, cough suppression is harmful

Antitussive Drugs

  • Used to stop or reduce coughing, suppress cough reflex by direct action on the CNS
  • Only used for non-productive cough, not for productive cough
  • Examples: Corticosteroids (Beclomethasone, Mometasone, Flunisolide)

Mucolytic Drugs

  • Reduce viscosity of sputum and respiratory secretions, making it easier to cough up
  • Examples: Bromhexine, Ambroxol, Acetylcysteine, Carbocysteine

Lower Respiratory Tract Disorders

  • COPD: progressive lung disease causing breathing problems, associated with lung inflammation
  • Asthma: episodic obstruction of respiratory passage, characterized by wheezing, shortness of breath, and difficulty breathing

Antiasthma Drugs

  • Bronchodilators:
    • β-receptor agonists: Salbutamol, Terbutaline, Salmeterol, Formoterol
    • Xanthine derivatives: Theophylline, Aminophylline
  • Leukotriene antagonists: block leukotriene effects, preventing bronchospasm, inflammation, and mucus secretion

Expectorants

  • Help remove mucus by stimulating secretory glands, loosening and thinning sputum
  • Used in non-productive and chronic cough
  • Examples: Guaifenesin, Potassium iodide

Histamines and Antihistamines

  • Histamine: released in response to allergic reactions, causing histamine effects (congestion, runny nose, watery eyes)
  • Antihistamines: bind to H1 histamine receptors, preventing histamine effects
  • Used to relieve cold symptoms, perennial or seasonal allergic rhinitis, allergic reactions
  • Examples: Diphenhydramine, Fexofenadine, Loratadine

Nasal Congestion and Decongestants

  • Nasal congestion: dilation of nasal blood vessels, transudation of fluid into tissue spaces, and swelling of nasal cavity
  • Causes: allergy, infection, inflammation
  • Decongestants:
    • Adrenergics: stimulate α-adrenergic receptors, causing vasoconstriction
    • Examples: Naphazoline, Oxymetazoline, Phenylephrine

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Description

This quiz covers the types of antitussives, including opioids and non-opioids, and expectorants that help remove mucus from the respiratory tract. Learn about their mechanisms and uses in treating coughs.

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