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Questions and Answers
Which receptors do 1st generation (typical) antipsychotic drugs primarily act as antagonists for?
Which receptors do 1st generation (typical) antipsychotic drugs primarily act as antagonists for?
What is the mechanism of action for 2nd generation (atypical) antipsychotic drugs?
What is the mechanism of action for 2nd generation (atypical) antipsychotic drugs?
Which category of antipsychotic agents includes Phenothiazines and Thioxanthenes?
Which category of antipsychotic agents includes Phenothiazines and Thioxanthenes?
What are the typical antipsychotics used to treat specifically?
What are the typical antipsychotics used to treat specifically?
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What is the main indication for Phenothiazines (major tranquilizers)?
What is the main indication for Phenothiazines (major tranquilizers)?
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Study Notes
Antipsychotic Drugs
- 1st generation (typical) antipsychotic drugs primarily act as antagonists for dopamine (D2) receptors.
Mechanism of Action
- 2nd generation (atypical) antipsychotic drugs have a mechanism of action that involves blocking serotonin 5-HT2 receptors and dopamine D2 receptors, with a higher affinity for serotonin receptors.
Antipsychotic Agents
- Phenothiazines and Thioxanthenes are categorized as typical antipsychotic agents.
Typical Antipsychotics
- Typical antipsychotics are used to treat psychotic symptoms, including hallucinations, delusions, and disorganized thinking and behavior, in conditions such as schizophrenia, bipolar disorder, and psychotic depression.
Phenothiazines
- The main indication for Phenothiazines (major tranquilizers) is to treat psychosis, particularly in schizophrenia.
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Description
Test your knowledge about the mechanism of action and uses of antipsychotic drugs, including first generation (typical) and second generation (atypical) drugs. Learn about their effects and potential side effects.