Antipsychotic Drugs and Schizophrenia Quiz

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What is the primary use of First Generation Antipsychotics?

To have a rapid antipsychotic effect

To reduce positive symptoms effectively (correct)

To primarily treat negative symptoms

To cure symptoms

Which of the following is a common adverse effect of First Generation Antipsychotics related to the cardiovascular system?

Endocrine effects

Metabolic effects

Sedation

Orthostatic hypotension (correct)

How are First Generation Antipsychotics usually administered?

Exclusively through oral tablets

Orally and through injection (correct)

Only through injection

Intravenously

What is a rare but serious reaction associated with First Generation Antipsychotics that can lead to death without treatment?

Neuroleptic malignant syndrome Signup and view all the answers

Which movement disorder can be a late-onset side effect caused by exposure to antipsychotic drugs?

Tardive dyskinesia Signup and view all the answers

What is the black box warning associated with First Generation Antipsychotics in elderly patients with dementia-related psychosis?

Increased mortality due to metabolic effects Signup and view all the answers

Which symptom does Tardive dyskinesia present as?

"Late-onset abnormal movements" Signup and view all the answers

'Depot, long-acting dosage forms for i.m. administration' refers to which aspect of First Generation Antipsychotics?

'Available for injection' Signup and view all the answers

Which type of antipsychotic drugs is generally associated with less extrapyramidal effects?

Second Generation Signup and view all the answers

What is the primary mechanism of action for First Generation antipsychotic drugs?

Blockade of D2 type dopamine receptors Signup and view all the answers

Which symptoms are associated with Cognitive symptoms of Schizophrenia?

Disordered thinking and learning problems Signup and view all the answers

What is the classification basis for First Generation antipsychotics?

Potency levels Signup and view all the answers

Which neurotransmitter receptors are thought to contribute to antipsychotic effects in Second Generation drugs?

D2 type dopamine and serotonin receptors Signup and view all the answers

Which neurotransmitter receptors do all antipsychotic drugs have the potential to block?

Norepinephrine, histamine, and dopamine receptors Signup and view all the answers

Which symptoms characterize the Cognitive symptoms of Schizophrenia?

'Lack of focus' and 'Learning problems' Signup and view all the answers

What is the primary factor that differentiates the potency levels among First Generation antipsychotic drugs?

'Dopamine receptor affinity' Signup and view all the answers

What is the primary symptom of tardive dyskinesia?

Jerky movements of the face with lip smacking and tongue protrusion Signup and view all the answers

How does Valbenazine (Ingrezza) work in treating tardive dyskinesia?

By reducing dopamine release at the synapse Signup and view all the answers

Which class of antipsychotics is known to cause fewer extrapyramidal symptoms like tardive dyskinesia?

Second Generation (Atypical) Antipsychotics Signup and view all the answers

Which antipsychotic is referred to as a 'dopamine stabilizer'?

Aripiprazole Signup and view all the answers

What is a common adverse effect of Second Generation (Atypical) Antipsychotics?

Dyslipidemia Signup and view all the answers

How do Atypical Antipsychotics differ from Conventional Antipsychotics?

They cause fewer extrapyramidal symptoms Signup and view all the answers

'Metabolic effects' commonly associated with Second Generation (Atypical) Antipsychotics include:

Weight gain, dyslipidemia, diabetes Signup and view all the answers

What role does Aripiprazole play in affecting dopamine receptors?

Weak stimulation of dopamine receptors Signup and view all the answers

Which neurotransmitter receptors do Second Generation (Atypical) Antipsychotics typically block?

D2 dopamine and serotonin receptors Signup and view all the answers