Antipsychotic Drugs and Schizophrenia Quiz
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Questions and Answers

What is the primary use of First Generation Antipsychotics?

  • To have a rapid antipsychotic effect
  • To reduce positive symptoms effectively (correct)
  • To primarily treat negative symptoms
  • To cure symptoms

Which of the following is a common adverse effect of First Generation Antipsychotics related to the cardiovascular system?

  • Endocrine effects
  • Metabolic effects
  • Sedation
  • Orthostatic hypotension (correct)

How are First Generation Antipsychotics usually administered?

  • Exclusively through oral tablets
  • Orally and through injection (correct)
  • Only through injection
  • Intravenously

What is a rare but serious reaction associated with First Generation Antipsychotics that can lead to death without treatment?

<p>Neuroleptic malignant syndrome (A)</p> Signup and view all the answers

Which movement disorder can be a late-onset side effect caused by exposure to antipsychotic drugs?

<p>Tardive dyskinesia (C)</p> Signup and view all the answers

What is the black box warning associated with First Generation Antipsychotics in elderly patients with dementia-related psychosis?

<p>Increased mortality due to metabolic effects (A)</p> Signup and view all the answers

Which symptom does Tardive dyskinesia present as?

<p>&quot;Late-onset abnormal movements&quot; (C)</p> Signup and view all the answers

'Depot, long-acting dosage forms for i.m. administration' refers to which aspect of First Generation Antipsychotics?

<p>'Available for injection' (B)</p> Signup and view all the answers

Which type of antipsychotic drugs is generally associated with less extrapyramidal effects?

<p>Second Generation (D)</p> Signup and view all the answers

What is the primary mechanism of action for First Generation antipsychotic drugs?

<p>Blockade of D2 type dopamine receptors (C)</p> Signup and view all the answers

Which symptoms are associated with Cognitive symptoms of Schizophrenia?

<p>Disordered thinking and learning problems (D)</p> Signup and view all the answers

What is the classification basis for First Generation antipsychotics?

<p>Potency levels (C)</p> Signup and view all the answers

Which neurotransmitter receptors are thought to contribute to antipsychotic effects in Second Generation drugs?

<p>D2 type dopamine and serotonin receptors (A)</p> Signup and view all the answers

Which neurotransmitter receptors do all antipsychotic drugs have the potential to block?

<p>Norepinephrine, histamine, and dopamine receptors (D)</p> Signup and view all the answers

Which symptoms characterize the Cognitive symptoms of Schizophrenia?

<p>'Lack of focus' and 'Learning problems' (C)</p> Signup and view all the answers

What is the primary factor that differentiates the potency levels among First Generation antipsychotic drugs?

<p>'Dopamine receptor affinity' (C)</p> Signup and view all the answers

What is the primary symptom of tardive dyskinesia?

<p>Jerky movements of the face with lip smacking and tongue protrusion (A)</p> Signup and view all the answers

How does Valbenazine (Ingrezza) work in treating tardive dyskinesia?

<p>By reducing dopamine release at the synapse (A)</p> Signup and view all the answers

Which class of antipsychotics is known to cause fewer extrapyramidal symptoms like tardive dyskinesia?

<p>Second Generation (Atypical) Antipsychotics (C)</p> Signup and view all the answers

Which antipsychotic is referred to as a 'dopamine stabilizer'?

<p>Aripiprazole (B)</p> Signup and view all the answers

What is a common adverse effect of Second Generation (Atypical) Antipsychotics?

<p>Dyslipidemia (D)</p> Signup and view all the answers

How do Atypical Antipsychotics differ from Conventional Antipsychotics?

<p>They cause fewer extrapyramidal symptoms (B)</p> Signup and view all the answers

'Metabolic effects' commonly associated with Second Generation (Atypical) Antipsychotics include:

<p>Weight gain, dyslipidemia, diabetes (A)</p> Signup and view all the answers

What role does Aripiprazole play in affecting dopamine receptors?

<p>Weak stimulation of dopamine receptors (B)</p> Signup and view all the answers

Which neurotransmitter receptors do Second Generation (Atypical) Antipsychotics typically block?

<p>D2 dopamine and serotonin receptors (C)</p> Signup and view all the answers

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