Antiplatelet Medications: Ticlopidine and Clopidogrel
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Questions and Answers

Ticlopidine is as effective as aspirin.

False

What is the primary use of Ticlopidine?

  • Treatment of hypertension
  • Prevention of TIA and stroke (correct)
  • Management of diabetes
  • Relief of anxiety
  • Which medication is an alternative to aspirin for secondary prevention of stroke?

  • Ticlopidine
  • Clopidogrel (correct)
  • Ibuprofen
  • Warfarin
  • What adverse effects limit the use of Ticlopidine?

    <p>Serious hematologic and gastrointestinal adverse effects</p> Signup and view all the answers

    Aspirin plus clopidogrel must be started within 24 hours of symptom onset in minor stroke or TIA.

    <p>True</p> Signup and view all the answers

    What genetic factors may affect clopidogrel's efficacy?

    <p>Polymorphisms in hepatic enzymes (CYP1A2, CYP3A4)</p> Signup and view all the answers

    Proton-pump inhibitors may increase the efficacy of clopidogrel.

    <p>False</p> Signup and view all the answers

    Study Notes

    Ticlopidine vs Aspirin

    • Ticlopidine is as effective as aspirin for secondary prevention of stroke
    • Ticlopidine is an alternative to aspirin for secondary prevention of stroke
    • Adverse effects limit the use of Ticlopidine

    Clopidogrel

    • Clopidogrel is an alternative to aspirin for secondary prevention of stroke
    • Aspirin plus clopidogrel must be started within 24 hours of symptom onset in minor stroke or TIA.
    • Clopidogrel's efficacy is affected by genetic factors
    • Proton-pump inhibitors may increase the efficacy of clopidogrel.

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    Description

    Test your knowledge on the use and mechanisms of Ticlopidine and Clopidogrel, two important antiplatelet medications. Learn about their effectiveness in preventing strokes and TIAs, as well as their side effects and drug interactions. This quiz will enhance your understanding of these critical drugs in cardiovascular health.

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