Antiplatelet Medications: Ticlopidine and Clopidogrel
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Questions and Answers

Ticlopidine is as effective as aspirin.

False (B)

What is the primary use of Ticlopidine?

  • Treatment of hypertension
  • Prevention of TIA and stroke (correct)
  • Management of diabetes
  • Relief of anxiety

Which medication is an alternative to aspirin for secondary prevention of stroke?

  • Ticlopidine
  • Clopidogrel (correct)
  • Ibuprofen
  • Warfarin

What adverse effects limit the use of Ticlopidine?

<p>Serious hematologic and gastrointestinal adverse effects</p> Signup and view all the answers

Aspirin plus clopidogrel must be started within 24 hours of symptom onset in minor stroke or TIA.

<p>True (A)</p> Signup and view all the answers

What genetic factors may affect clopidogrel's efficacy?

<p>Polymorphisms in hepatic enzymes (CYP1A2, CYP3A4)</p> Signup and view all the answers

Proton-pump inhibitors may increase the efficacy of clopidogrel.

<p>False (B)</p> Signup and view all the answers

Study Notes

Ticlopidine vs Aspirin

  • Ticlopidine is as effective as aspirin for secondary prevention of stroke
  • Ticlopidine is an alternative to aspirin for secondary prevention of stroke
  • Adverse effects limit the use of Ticlopidine

Clopidogrel

  • Clopidogrel is an alternative to aspirin for secondary prevention of stroke
  • Aspirin plus clopidogrel must be started within 24 hours of symptom onset in minor stroke or TIA.
  • Clopidogrel's efficacy is affected by genetic factors
  • Proton-pump inhibitors may increase the efficacy of clopidogrel.

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Description

Test your knowledge on the use and mechanisms of Ticlopidine and Clopidogrel, two important antiplatelet medications. Learn about their effectiveness in preventing strokes and TIAs, as well as their side effects and drug interactions. This quiz will enhance your understanding of these critical drugs in cardiovascular health.

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