18 Questions
What is the mechanism of action of dabigatran etexilate?
Direct thrombin inhibitor
What is the main use of aspirin as an antiplatelet drug?
Prevention of thrombosis in arteries
Which adverse effect is specifically associated with ADP receptor blockers like clopidogrel and ticlopidine?
Increased risk of bleeds
Which condition is not a use for thrombolytics?
Hypertension (HTN)
What is the major adverse effect of heparin sodium (unfractionated)?
Hemorrhage
Which drug is used for stroke prevention in nonvalvular atrial fibrillation?
Rivaroxaban
Which condition is a contraindication for the use of unfractionated heparin?
Disseminated Intravascular Coagulation (DIC)
When should thrombolytics be avoided?
After recent major surgery
When transitioning from IV Heparin to PO Warfarin, for how many days should a patient receive both drugs?
2-3 days
What is the antidote for rivaroxaban and apixaban?
Andexanet
What is the main adverse effect associated with thrombolytics?
Brain Hemorrhage
When should lab draws be done for patients on continuous infusion of heparin sodium?
Anytime
What is the antagonist (antidote) for warfarin?
Phytonadione (vitamin K)
Which clotting factors does warfarin inhibit the synthesis of?
Factor II and IV
What is the lab value used to monitor warfarin therapy?
International Normalized Ratio (INR)
What is the recommended duration for dual antiplatelet therapy with ADP receptor blockers like clopidogrel?
>12 months
What is the urgent reversal agent for major or life-threatening hemorrhage in warfarin therapy?
Prothrombin Complex Concentrate (KCentra)
What is the effect of high vitamin K intake on warfarin therapy, and what should patients be taught regarding this?
Increases INR; patients should increase vitamin K intake
Test your knowledge on the mechanism of action, uses, adverse effects, contraindications, and nursing implications of antiplatelet drugs. Explore prototypes like aspirin and learn about drug classes that help prevent conditions such as heart attacks and strokes.
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