Antiplatelet Drugs and Nursing Considerations
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Questions and Answers

What is the primary action of oral antiplatelet drugs like aspirin and clopidogrel?

  • Suppress platelet aggregation (correct)
  • Enhance clot formation
  • Increase platelet formation
  • Inhibit anticoagulant deficiencies
  • Which of the following is a common consideration before administering oral antiplatelet drugs?

  • History of upper GI bleeding (correct)
  • Recent use of antibiotics
  • Recent surgery for heart disease
  • Presence of high blood pressure
  • What should be monitored during the administration of intravenous antiplatelet drugs?

  • Daily weight
  • CBC and clotting studies (correct)
  • Renal function tests
  • Serum glucose levels
  • Which of the following statements about the use of aspirin and clopidogrel is true?

    <p>The daily dose of aspirin for antiplatelet effect is low, typically 80 mg/day.</p> Signup and view all the answers

    What is a key difference between oral and intravenous antiplatelet drugs?

    <p>Oral drugs are less effective than intravenous drugs.</p> Signup and view all the answers

    What should patients taking antiplatelet drugs do if they seek healthcare for other conditions?

    <p>Inform care providers about their antiplatelet medication.</p> Signup and view all the answers

    Which symptoms should be reported by patients using oral antiplatelet drugs?

    <p>Unusual bruising or excessive bleeding</p> Signup and view all the answers

    What potential risk is increased with the use of intravenous antiplatelet drugs compared to oral ones?

    <p>Greater risk of bleeding</p> Signup and view all the answers

    Study Notes

    Oral Antiplatelet Drugs

    • Examples: aspirin, clopidogrel
    • Mechanism of Action: Inhibit platelet aggregation in the arteries, preventing thrombus formation
    • Aspirin and clopidogrel block different platelet activation pathways.
    • Low-dose aspirin (80 mg/day) is typically used for antiplatelet effects.

    Nursing Considerations for Oral Antiplatelet Drugs

    • Assess history of intracranial hemorrhage, upper GI bleeding, peptic ulcer disease, or known bleeding tendencies.
    • Monitor for and report increased bruising, petechiae, purpura, and apparent or occult bleeding.
    • Do not administer concurrently with warfarin.

    Intravenous Antiplatelet Drugs

    • Examples: abciximab, eptifibatide, tirofiban
    • Mechanism of Action: Block the final common pathway of platelet activation, making them more effective than oral antiplatelet drugs.
    • Increased risk of bleeding compared to oral antiplatelet drugs.

    Nursing Considerations for Intravenous Antiplatelet Drugs

    • Determine history of bleeding disorders, intracranial hemorrhage, or recent trauma or surgery.
    • Inquire about recent use of oral antiplatelet or anticoagulant drugs.
    • Monitor CBC, including hemoglobin, hematocrit, and platelet count, and clotting studies.
    • Monitor vital signs and ECG during therapy.
    • Maintain separate IV lines for blood draws and administration of other drugs during infusion.
    • Closely observe for and immediately report anaphylaxis or bleeding uncontrolled by pressure.
    • Keep resuscitation equipment readily available.
    • Maintain bedrest during infusion.

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    Description

    This quiz covers oral and intravenous antiplatelet drugs, detailing their mechanisms of action and nursing considerations. Learn about the differences between drugs like aspirin and clopidogrel, as well as the precautions needed when administering these medications. Test your knowledge on key concepts essential for nursing practice in pharmacology.

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