56 Questions
Which antibiotic is recommended for treating Clostridioides difficile infection?
Vancomycin (oral)
Which antibiotic is effective against Atypical Organisms such as Mycoplasma pneumoniae?
Azithromycin
Which antibiotic is suitable for treating infections caused by Pseudomonas aeruginosa?
Piperacillin/Tazobactam
Which antibiotic is a drug of choice for Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs)?
Doxycycline
Which antibiotic is recommended for treating Vancomycin-resistant Enterococcus (VRE) infections?
Daptomycin
What is the drug of choice for Acinetobacter baumannii infections?
Linezolid
Which antibiotic is recommended for treating Bacteroides fragilis infections?
Metronidazole
Name three antibiotics recommended for treating Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs).
SMX/TMP, Doxycycline, Clindamycin
What is the drug of choice for treating Vancomycin-resistant Enterococcus (VRE) infections?
Daptomycin
Which antibiotic is recommended for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci?
Vancomycin
Name an antibiotic effective against Nosocomial MRSA.
Linezolid
Which antibiotic is recommended for treating Clostridioides difficile infection?
Vancomycin (oral), Fidaxomicin, Metronidazole
What antibiotics are effective against Atypical Organisms such as Mycoplasma pneumoniae?
Azithromycin, clarithromycin
What antibiotics are suitable for treating infections caused by Pseudomonas aeruginosa?
Piperacillin/Tazobactam, Ceftolozane/Tazobactam, Cefepime (high-dose), Aminoglycosides
Match the following antibiotics with their primary usage:
Vancomycin (oral) = Clostridioides difficile Infection Fidaxomicin = Clostridioides difficile Infection Metronidazole = Clostridioides difficile Infection Azithromycin, clarithromycin = Atypical Organisms
Match the following antibiotics with the bacteria they are effective against:
Ampicillin/ Sulbactam = Extended spectrum beta-lactamase producing Gram-negative rods (ESBL GNR) - E. coli, K. pneumoniae, P. mirabilis Ceftolozane/Tazobactam = Pseudomonas aeruginosa Cefepime (high-dose) = Pseudomonas aeruginosa Piperacillin/Tazobactam = Pseudomonas aeruginosa
Match the following antibiotics with the type of infection they are suitable for treating:
Ceftazidime/Avibactam = Cystitis only nitrofurantoin, fosfomycin = Cystitis only Colistimethate polymyxin B = Cystitis only Cystitis only: fosfomycin = Cystitis only
Match the following antibiotics with their recommended usage for Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs):
SMX/TMP = Recommended Daptomycin = Not recommended Ceftolozane/Tazobactam = Not recommended Linezolid = Recommended
Match the following antibiotics with their recommended usage for Vancomycin-resistant Enterococcus (VRE) infections:
Ceftazidime/Avibactam = Not recommended Daptomycin = Recommended Colistimethate, polymyxin B = Recommended Vancomycin = Not recommended
Match the following antibiotics with their recommended usage for Carbapenem-resistant Gram-negative rods (CRE):
Linezolid = Not recommended Ceftazidime/Avibactam = Recommended Tigecycline = Recommended Quinupristin/Dalfopristin = Not recommended
Match the following antibiotics with their recommended usage for Acinetobacter baumannii infections:
Rifampin = Recommended Telavancin = Recommended Ceftolozane/Tazobactam = Not recommended Vancomycin = Not recommended
Which antibiotic is recommended for treating Clostridioides difficile infection?
Vancomycin (oral)
Which antibiotic is effective against Atypical Organisms such as Mycoplasma pneumoniae?
Doxycycline
Which antibiotic is recommended for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci?
Cefepime (high-dose)
Which antibiotic is recommended for treating Clostridioides difficile infection?
Vancomycin
What is the drug of choice for Acinetobacter baumannii infections?
Colistimethate
Which antibiotic is effective against Atypical Organisms such as Mycoplasma pneumoniae?
Doxycycline
What antibiotics are suitable for treating infections caused by Pseudomonas aeruginosa?
Ceftolozane/Tazobactam
Which antibiotics are recommended for treating Clostridioides difficile infection?
Vancomycin (oral), Fidaxomicin, Metronidazole
Name three antibiotics effective against Pseudomonas aeruginosa infections.
Piperacillin/Tazobactam, Ceftolozane/Tazobactam, Carbapenems
What antibiotics are suitable for treating Extended Spectrum Beta-lactamase producing Gram-negative rods (ESBL GNR) infections?
Carbapenems, Tigecycline, Ceftolozane/Tazobactam
Which antibiotics are recommended for treating Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs)?
SMX/TMP, Doxycycline, Minocycline, Clindamycin, Linezolid
What are the drug options for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci?
Vancomycin, Linezolid, Tedizolid, Ceftazidime/Avibactam, Cefepime, Tigecycline, Ceftazidime, Clindamycin, Moxifloxacin, Daptomycin, Ceftolozane/Tazobactam, Ceftaroline, Carbapenems, Telavancin, Ciprofloxacin, Levofloxacin, Oritavancin, Aztreonam, Dalbavancin, Aminoglycosides, Quinupristin/Dalfopristin, Colistimethate, Polymyxin B, Tigecycline
What antibiotics are recommended for treating Vancomycin-resistant Enterococcus (VRE) infections?
Daptomycin, Linezolid, Pen G, Ampicillin, Carbapenems
Which antibiotics are effective against Acinetobacter baumannii infections?
Vancomycin, Linezolid, Daptomycin, Rifampin, Telavancin, Carbapenems
Match the following antibiotics with the bacteria they are effective against:
Vancomycin (oral) = Clostridioides difficile Ceftolozane/Tazobactam = Pseudomonas aeruginosa Fidaxomicin = Clostridioides difficile Tigecycline = Extended spectrum beta-lactamase producing Gram-negative rods (ESBL GNR)
Match the following antibiotics with their recommended usage for Acinetobacter baumannii infections:
Carbapenems = Effective Aminoglycosides = Effective Colistimethate polymyxin B = Effective Quinolones = Ineffective
Match the following antibiotics with their recommended usage for Extended Spectrum Beta-lactamase producing Gram-negative rods (ESBL GNR) infections:
Carbapenems = Effective Cefepime (high-dose) = Effective Quinolones = Ineffective Ampicillin/Sulbactam = Ineffective
Is daptomycin recommended for treating Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs)?
True
Is nitrofurantoin suitable for treating cystitis caused by Carbapenem-resistant Gram-negative rods (CRE)?
False
Is rifampin recommended for treating Nosocomial MRSA?
True
Is vancomycin recommended for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci?
True
Match the following antibiotics with their recommended usage for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci:
Vancomycin = Consider using alternative if MIC > 2 Linezolid = Tedizolid Ceftazidime/Avibactam = Cefepime Tigecycline = Ceftazidime
Match the following antibiotics with the bacteria they are effective against:
SMX/TMP = Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) Daptomycin = VRE (E. faecium) Ceftazidime/Avibactam = Carbapenem-resistant Gram-negative rods (CRE) Colistimethate, polymyxin B = Acinetobacter baumannii
Match the following antibiotics with their recommended usage for Cystitis only:
Nitrofurantoin = Fosfomycin Doxycycline = Minocycline Clindamycin = Linezolid Tigecycline = Ceftazidime
Match the following antibiotics with their recommended usage for Nosocomial MRSA:
Vancomycin = Consider using alternative if MIC > 2 Linezolid = Daptomycin (not in pneumonia) Rifampin = Telavancin Colistimethate, polymyxin B = Tigecycline
Match the antibiotic with the bacteria it is effective against:
Linezolid = VRE (E. faecium) Daptomycin = Nosocomial MRSA Tigecycline = Acinetobacter baumannii Vancomycin = Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA)
Match the antibiotic with its recommended usage for more severe SSTIs requiring IV treatment or hospitalization, covering MRSA and Streptococci:
Vancomycin = Cover MRSA and Streptococci Linezolid = Cover MRSA and Streptococci Ceftazidime = Cover MRSA and Streptococci Tigecycline = Cover MRSA and Streptococci
Match the antibiotic with the type of infection it is suitable for treating:
SMX/TMP = Community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs) Doxycycline = Cystitis only Clindamycin = More severe SSTIs requiring IV treatment or hospitalization Nitrofurantoin = Cystitis only
Match the antibiotic with its recommended usage for Vancomycin-resistant Enterococcus (VRE) infections:
Daptomycin = E. faecalis Linezolid = E. faecalis Carbapenems = E. faecalis Pen G or ampicillin = E. faecalis
Vancomycin is recommended for treating Clostridioides difficile infection?
False
Doxycycline is effective against Atypical Organisms such as Mycoplasma pneumoniae?
True
Tigecycline is suitable for treating Cystitis only?
False
Vancomycin is the drug of choice for treating Clostridioides difficile infection
True
Tigecycline is recommended for treating Carbapenem-resistant Gram-negative rods (CRE) infections
True
Azithromycin and clarithromycin are effective against Atypical Organisms such as Mycoplasma pneumoniae
True
Study Notes
Community-Associated Methicillin-Resistant Staphylococcus aureus (CA MRSA)
- CA MRSA skin and soft tissue infections (SSTIs):
- Treatment options: SMX/TMP, doxycycline, minocycline, clindamycin*, linezolid
- More severe SSTIs requiring IV treatment or hospitalization:
- Cover MRSA and Streptococci with:
- Vancomycin (consider alternative if MIC > 2)
- Linezolid, tedizolid
- Ceftazidime/Avibactam
- Cefepime
- Tigecycline
- Cover MRSA and Streptococci with:
Vancomycin-Resistant Enterococcus (VRE)
- VRE (E. faecium):
- Treatment options: daptomycin, carbapenems
- VRE (E. faecalis):
- Treatment options: penicillin G or ampicillin, linezolid, daptomycin, carbapenems
Carbapenem-Resistant Gram-Negative Rods (CRE)
- CRE:
- Treatment options: linezolid, ceftazidime/Avibactam, quinupristin/dalfopristin, colistimethate, polymyxin B, tigecycline
Bacteroides fragilis
- Treatment options: metronidazole, beta-lactam/beta-lactamase inhibitor
Extended Spectrum Beta-Lactamase (ESBL) Producing Gram-Negative Rods (ESBL GNR)
- ESBL GNR (E. coli, K. pneumoniae, P. mirabilis):
- Treatment options: carbapenems, tigecycline, ceftolozane/Tazobactam
- Cystitis only: nitrofurantoin, fosfomycin, doxycycline
Pseudomonas aeruginosa
- Treatment options: piperacillin/Tazobactam, cefotetan, cefoxitin, cephalosporins (except 1st generation), carbapenems, SMX/TMP, aminoglycosides, quinolones, cefepime (high dose)
Clostridium difficile Infection
- Treatment options: vancomycin (oral), fidaxomicin, metronidazole
Atypical Organisms
- Treatment options: azithromycin, clarithromycin, carbapenems (except ertapenem), doxycycline, minocycline, ampicillin/sulbactam, quinolones, minocycline, HNPEK, beta-lactam/beta-lactamase inhibitor, tigecycline, quinolones, SMX/TMP
Test your knowledge of drugs of choice and active drugs for specific pathogens with this RxPrep summary tables quiz. Identify the most effective treatment options for community-associated MRSA, VRE, and carbapenem-resistant Gram-negative rods, among others. Sharpen your understanding of antimicrobial therapy with this comprehensive quiz.
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