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Questions and Answers
What is the main consideration for selective toxicity of an antimicrobial drug?
What is the main consideration for selective toxicity of an antimicrobial drug?
- Antibiotic Resistance
- Molecule size
- Tissue penetration
- Safety profile (correct)
What does the term 'spectrum' refer to in relation to antimicrobial drugs?
What does the term 'spectrum' refer to in relation to antimicrobial drugs?
- Tissue penetration of the drug
- Microbes targeted by the drug (correct)
- Molecule size of the drug
- Mechanisms of antibiotic resistance
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
- Treatment before the specific microbe is identified (correct)
- Treatment based on safety profile
- Treatment based on tissue penetration
- Treatment based on resistance patterns
What can antibiotic resistance occur via in bacteria?
What can antibiotic resistance occur via in bacteria?
What is one of the factors influencing tissue penetration of an antibiotic?
What is one of the factors influencing tissue penetration of an antibiotic?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
What is the minimal inhibitory concentration (MIC)?
What is the minimal inhibitory concentration (MIC)?
Which type of drugs rely on the host defenses to kill the bacteria?
Which type of drugs rely on the host defenses to kill the bacteria?
What is the mechanism of action of natural penicillins?
What is the mechanism of action of natural penicillins?
Which drug is considered the treatment of choice in syphilis?
Which drug is considered the treatment of choice in syphilis?
What is the activity of antipseudomonal penicillins?
What is the activity of antipseudomonal penicillins?
What is the most common adverse effect of penicillins?
What is the most common adverse effect of penicillins?
Which drug is known as an extended-spectrum penicillin?
Which drug is known as an extended-spectrum penicillin?
What do beta-lactamase inhibitors do when combined with penicillins?
What do beta-lactamase inhibitors do when combined with penicillins?
Among patients with a positive skin test to penicillin, what percentage are at risk for cross-reactivity with cephalosporins according to more recent observational studies?
Among patients with a positive skin test to penicillin, what percentage are at risk for cross-reactivity with cephalosporins according to more recent observational studies?
What is the main consideration for tissue penetration of an antibiotic?
What is the main consideration for tissue penetration of an antibiotic?
How can antibiotic resistance occur in bacteria?
How can antibiotic resistance occur in bacteria?
What aspect does the term 'spectrum' refer to in relation to antimicrobial drugs?
What aspect does the term 'spectrum' refer to in relation to antimicrobial drugs?
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
What is one of the factors influencing selective toxicity of an antimicrobial drug?
What is one of the factors influencing selective toxicity of an antimicrobial drug?
What is the minimal inhibitory concentration (MIC)?
What is the minimal inhibitory concentration (MIC)?
How do bacteriostatic drugs differ from bactericidal drugs?
How do bacteriostatic drugs differ from bactericidal drugs?
What is the mechanism of action of natural penicillins?
What is the mechanism of action of natural penicillins?
What is the main consideration for selective toxicity of an antimicrobial drug?
What is the main consideration for selective toxicity of an antimicrobial drug?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
What contributes to the limited options for severe, life-threatening infections in the context of antimicrobial therapy?
Which drug is known as an extended-spectrum penicillin?
Which drug is known as an extended-spectrum penicillin?
What does the term 'spectrum' refer to in relation to antimicrobial drugs?
What does the term 'spectrum' refer to in relation to antimicrobial drugs?
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
In the context of antimicrobial therapy, what does 'empiric treatment' involve?
What can antibiotic resistance occur via in bacteria?
What can antibiotic resistance occur via in bacteria?
What is one of the factors influencing tissue penetration of an antibiotic?
What is one of the factors influencing tissue penetration of an antibiotic?
What is the most common adverse effect of penicillins?
What is the most common adverse effect of penicillins?
Which of the following antibiotics is most active against Pseudomonas?
Which of the following antibiotics is most active against Pseudomonas?
Which antibiotic is taken orally as a bowel decontaminant and used topically?
Which antibiotic is taken orally as a bowel decontaminant and used topically?
Which antibiotic is most commonly used for meningitis in infants?
Which antibiotic is most commonly used for meningitis in infants?
Which antibiotic is less resistant and used to monitor increased plasma levels of toxins?
Which antibiotic is less resistant and used to monitor increased plasma levels of toxins?
What is the adverse effect of isoniazid (vitamin B6 deficiency)?
What is the adverse effect of isoniazid (vitamin B6 deficiency)?
Which anti-tuberculous drug is contraindicated in pregnancy due to its vestibular and otoxic effects?
Which anti-tuberculous drug is contraindicated in pregnancy due to its vestibular and otoxic effects?
What is the main adverse effect of pyrazinamide?
What is the main adverse effect of pyrazinamide?
Which anti-tuberculous drug is the only bacteriostatic first-line drug?
Which anti-tuberculous drug is the only bacteriostatic first-line drug?
What is the mechanism of action of polyene antifungal agents?
What is the mechanism of action of polyene antifungal agents?
Which antifungal agent penetrates the central nervous system (CNS)?
Which antifungal agent penetrates the central nervous system (CNS)?
What is a common adverse effect of azole antifungal agents?
What is a common adverse effect of azole antifungal agents?
Which antifungal agent is used for dermatophytosis of the skin, hair, and nails?
Which antifungal agent is used for dermatophytosis of the skin, hair, and nails?
What is the most significant side effect associated with itraconazole and fluconazole (Triazoles)?
What is the most significant side effect associated with itraconazole and fluconazole (Triazoles)?
Which antifungal agent is used for oral thrush and candida esophagitis?
Which antifungal agent is used for oral thrush and candida esophagitis?
What is the common adverse effect of Streptomycin?
What is the common adverse effect of Streptomycin?
What is the primary mechanism of action of Ethambutol?
What is the primary mechanism of action of Ethambutol?
What are the adverse effects associated with minocycline?
What are the adverse effects associated with minocycline?
Which antibiotic should not be taken with dairy products?
Which antibiotic should not be taken with dairy products?
Which antibiotic is used in combination regimens for H. pylori?
Which antibiotic is used in combination regimens for H. pylori?
What is the spectrum of activity of macrolides such as erythromycin, azithromycin, and clarithromycin?
What is the spectrum of activity of macrolides such as erythromycin, azithromycin, and clarithromycin?
Which antibiotic is unrelated to other antibiotics and is used topically for acne and bacterial vaginosis?
Which antibiotic is unrelated to other antibiotics and is used topically for acne and bacterial vaginosis?
Which antibiotic inhibits bacterial DNA synthesis via inhibition of DNA topoisomerases?
Which antibiotic inhibits bacterial DNA synthesis via inhibition of DNA topoisomerases?
What are the uses of daptomycin?
What are the uses of daptomycin?
What are the adverse effects associated with antifolate drugs like trimethoprim-sulfamethoxazole (Bactrim, Septra)?
What are the adverse effects associated with antifolate drugs like trimethoprim-sulfamethoxazole (Bactrim, Septra)?
Which antibiotic is used to treat urinary tract infections, sinusitis, bronchitis, and MRSA?
Which antibiotic is used to treat urinary tract infections, sinusitis, bronchitis, and MRSA?
What is the mechanism of action of mupirocin (Bactroban)?
What is the mechanism of action of mupirocin (Bactroban)?
What antibiotic is known to cause prolongation of the QT interval and has been associated with a small increase in cardiovascular deaths in those with pre-existing cardiac disease?
What antibiotic is known to cause prolongation of the QT interval and has been associated with a small increase in cardiovascular deaths in those with pre-existing cardiac disease?
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