Antimicrobial Resistance Quiz
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Questions and Answers

Which of the following factors can accelerate the evolution of drug resistance?

  • Overuse (correct)
  • Proper use
  • Patient compliance
  • Underuse

What are the common mechanisms of drug resistance?

  • Horizontal gene transfer only
  • None of the above
  • Both chromosomal mutations and horizontal gene transfer (correct)
  • Chromosomal mutations only

What are multidrug-resistant microbes (MDRs)?

  • Microbes that are resistant to one antimicrobial
  • Microbes that are resistant to all antimicrobials
  • Microbes that are resistant to multiple antimicrobials (correct)
  • Microbes that are not resistant to any antimicrobials

Which of the following is a clinically important superbug responsible for many nosocomial infections?

<p>Enterococcus faecium (C)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A pathogen that causes skin infections, pneumonia, and septicemia (B)</p> Signup and view all the answers

What is Vancomycin-resistant enterococci (VRE)?

<p>A pathogen that is resistant to vancomycin (D)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Bacteria that are resistant to multiple antimicrobials (C)</p> Signup and view all the answers

What are Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>Bacteria that are resistant to multiple antimicrobials (D)</p> Signup and view all the answers

What is the main concern with Multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>They are resistant to multiple antimicrobials (D)</p> Signup and view all the answers

What is the need for rapid clinical identification methods?

<p>To limit the spread of resistant bacteria (B)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (D)</p> Signup and view all the answers

Which of the following factors can accelerate the evolution of drug resistance?

<p>Overuse (D)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Both chromosomal mutations and horizontal gene transfer (B)</p> Signup and view all the answers

What are multidrug-resistant microbes (MDRs)?

<p>Microbes that are resistant to multiple antimicrobials (D)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections?

<p>Enterococcus faecium (A)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A pathogen that causes skin infections, pneumonia, and septicemia (A)</p> Signup and view all the answers

What is Vancomycin-resistant enterococci (VRE)?

<p>A pathogen that is resistant to vancomycin (D)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Bacteria that are resistant to multiple antimicrobials (A)</p> Signup and view all the answers

What are Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>Bacteria that are resistant to multiple antimicrobials (A)</p> Signup and view all the answers

What is the main concern with Multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>They are resistant to multiple antimicrobials (C)</p> Signup and view all the answers

What is the need for rapid clinical identification methods?

<p>To limit the spread of resistant bacteria (D)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (A)</p> Signup and view all the answers

Which of the following factors can accelerate the evolution of drug resistance?

<p>Misuse (C)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (B)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Enzymatic modification, prevention of cellular uptake, and target overproduction (C)</p> Signup and view all the answers

What is a multidrug-resistant microbe (MDR)?

<p>A microbe that is resistant to multiple antimicrobials (A)</p> Signup and view all the answers

What is cross resistance?

<p>Resistance to multiple drugs via a single resistance mechanism (A)</p> Signup and view all the answers

Which superbugs are responsible for many nosocomial infections?

<p>ESKAPE pathogens (A)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A pathogen that is resistant to all available β-lactams (B)</p> Signup and view all the answers

What is the cause of the emergence of Vancomycin-resistant enterococci (VRE), vancomycin-resistant S. aureus (VRSA), and vancomycin-intermediate S. aureus (VISA)?

<p>Increased use of vancomycin (A)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota (B)</p> Signup and view all the answers

What are MDR-TB and XDR-TB?

<p>Bacterial infections that are resistant to multiple antibiotics (D)</p> Signup and view all the answers

What is necessary to limit the spread of resistant bacteria?

<p>Rapid clinical identification methods (B)</p> Signup and view all the answers

What is necessary to combat antimicrobial resistance?

<p>All of the above (B)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (A)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (D)</p> Signup and view all the answers

Which of the following is NOT a common mechanism of drug resistance?

<p>Target mimicry and target overexpression (C)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to a single antimicrobial, while cross resistance confers resistance to multiple drugs via a single resistance mechanism (B)</p> Signup and view all the answers

Which of the following is NOT one of the ESKAPE pathogens?

<p>Escherichia coli (D)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA) resistant to?

<p>All available β-lactams (A)</p> Signup and view all the answers

Which of the following is NOT a vancomycin-resistant bacteria?

<p>Streptococcus pyogenes (D)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota and can cause opportunistic infections in hospitalized patients (A)</p> Signup and view all the answers

What is the difference between multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>MDR-TB is resistant to a single antimicrobial, while XDR-TB is resistant to multiple antimicrobials (B)</p> Signup and view all the answers

What is the main concern with the emergence of multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>They limit treatment options and increase the risk of treatment failure and death (C)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary to limit the spread of resistant bacteria?

<p>To identify infected patients and implement appropriate infection control measures (D)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (C)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (A)</p> Signup and view all the answers

Which of the following is NOT a common mechanism of drug resistance?

<p>Target underproduction or enzymatic bypass (A)</p> Signup and view all the answers

Which of the following is a multidrug-resistant bacteria that is typically a member of the intestinal microbiota but can cause opportunistic infections in hospitalized patients?

<p>Klebsiella pneumoniae (C)</p> Signup and view all the answers

Which of the following is a superbug responsible for many nosocomial infections?

<p>Pseudomonas aeruginosa (C)</p> Signup and view all the answers

Which of the following is a widespread opportunistic pathogen that causes skin infections, pneumonia, and septicemia, and is resistant to all available β-lactams?

<p>Methicillin-resistant Staphylococcus aureus (MRSA) (B)</p> Signup and view all the answers

Which of the following is a multidrug-resistant Mycobacterium tuberculosis that results from the incorrect use of antimicrobials for tuberculosis treatment?

<p>MDR-TB (B)</p> Signup and view all the answers

Which of the following is a superbug that exhibits high resistance to vancomycin?

<p>Vancomycin-resistant enterococci (VRE) (D)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections and is resistant to multiple antimicrobials?

<p>Acinetobacter baumannii (B)</p> Signup and view all the answers

Which of the following is NOT a concern with Multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>Increased patient compliance (A)</p> Signup and view all the answers

Which of the following is a rapidly emerging threat in clinical settings and is resistant to most available antibiotics?

<p>Extended-spectrum β-lactamase–producing gram-negative pathogens (C)</p> Signup and view all the answers

What is the main concern with the increased use of vancomycin?

<p>Emergence of multidrug-resistant microbes (MDRs) (D)</p> Signup and view all the answers

What is necessary to combat antimicrobial resistance?

<p>Both A and B (A)</p> Signup and view all the answers

Which of the following is NOT a factor that can accelerate the evolution of drug resistance?

<p>Patient compliance (D)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (A)</p> Signup and view all the answers

Which of the following is NOT a common mechanism of drug resistance?

<p>Target elimination (A)</p> Signup and view all the answers

What is cross resistance?

<p>Resistance to multiple drugs via a single resistance mechanism (B)</p> Signup and view all the answers

Which of the following is NOT one of the ESKAPE pathogens?

<p>Escherichia coli (C)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA) resistant to?

<p>All available β-lactams (A)</p> Signup and view all the answers

What is the difference between vancomycin-resistant enterococci (VRE) and vancomycin-resistant S. aureus (VRSA)?

<p>VRE exhibits high resistance to vancomycin while VRSA exhibits intermediate resistance (A)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Bacteria that produce enzymes that inactivate β-lactam antibiotics (B)</p> Signup and view all the answers

What is the difference between multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>MDR-TB is resistant to two first-line drugs while XDR-TB is resistant to three or more second-line drugs (A)</p> Signup and view all the answers

What is the main concern with multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>They limit treatment options (D)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary?

<p>To limit the spread of resistant bacteria (A)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>Development of new antibiotics and prudent antimicrobial use (D)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (A)</p> Signup and view all the answers

What are the two ways resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (B)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Enzymatic modification and inactivation of the drug, prevention of cellular uptake or efflux, target modification, target overproduction or enzymatic bypass, and target mimicry (C)</p> Signup and view all the answers

What is cross resistance?

<p>Resistance to multiple drugs via a single resistance mechanism (C)</p> Signup and view all the answers

What are the ESKAPE pathogens?

<p>Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (D)</p> Signup and view all the answers

What is MRSA?

<p>A widespread opportunistic pathogen that causes skin infections, pneumonia, and septicemia (C)</p> Signup and view all the answers

What are VRE, VRSA, and VISA?

<p>Vancomycin-resistant bacteria (D)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota but can cause opportunistic infections in hospitalized patients (A)</p> Signup and view all the answers

What are MDR-TB and XDR-TB?

<p>Drug-resistant tuberculosis strains (B)</p> Signup and view all the answers

What is the main concern with MDRs and cross resistance in clinical settings?

<p>The spread of resistant bacteria (D)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary?

<p>To limit the spread of resistant bacteria (A)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>Prudent antimicrobial use and patient compliance (C)</p> Signup and view all the answers

Which of the following factors can contribute to the evolution of antimicrobial resistance?

<p>Misuse of antimicrobial drugs (D)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (D)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Target mimicry and enzymatic modification (D)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to multiple antimicrobials and cross resistance confers resistance to a single drug (B)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections?

<p>Klebsiella pneumoniae (A)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A drug that is resistant to all available β-lactams (C)</p> Signup and view all the answers

What caused the emergence of vancomycin-resistant enterococci (VRE), vancomycin-resistant S. aureus (VRSA), and vancomycin-intermediate S. aureus (VISA)?

<p>Increased use of vancomycin (B)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Bacteria that are typically members of the intestinal microbiota (B)</p> Signup and view all the answers

What is the main concern with Multidrug-resistant microbes (MDRs) and cross resistance in clinical settings?

<p>The spread of resistant bacteria (D)</p> Signup and view all the answers

What is the significance of Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>They are of significant global concern (C)</p> Signup and view all the answers

What is necessary to limit the spread of resistant bacteria?

<p>The development of rapid clinical identification methods (B)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>Prudent antimicrobial use and the development of rapid clinical identification methods (A)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (D)</p> Signup and view all the answers

Which of the following is NOT a common mechanism of drug resistance?

<p>Target underproduction or enzymatic bypass (B)</p> Signup and view all the answers

Which of the following is a multidrug-resistant bacteria that is typically a member of the intestinal microbiota but can cause opportunistic infections in hospitalized patients?

<p>Klebsiella pneumoniae (B)</p> Signup and view all the answers

Which of the following is a superbug responsible for many nosocomial infections?

<p>Staphylococcus aureus (D)</p> Signup and view all the answers

Which of the following is a widespread opportunistic pathogen that is resistant to all available β-lactams?

<p>Staphylococcus aureus (B)</p> Signup and view all the answers

Which of the following is a multidrug-resistant Mycobacterium tuberculosis that is of significant global concern and results from the incorrect use of antimicrobials for tuberculosis treatment?

<p>MDR-TB (A)</p> Signup and view all the answers

Which of the following is NOT a vancomycin-resistant bacteria?

<p>K. pneumoniae (C)</p> Signup and view all the answers

Which of the following is NOT a concern in clinical settings regarding multidrug-resistant microbes (MDRs)?

<p>MDRs being susceptible to all available antimicrobials (C)</p> Signup and view all the answers

Which of the following is a mechanism of drug resistance where the microbe prevents the drug from entering the cell or pumps it out of the cell?

<p>Prevention of cellular uptake or efflux (A)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections and can be multidrug-resistant?

<p>Pseudomonas aeruginosa (B)</p> Signup and view all the answers

Which of the following is a mechanism of drug resistance where the microbe produces an enzyme that inactivates the drug?

<p>Enzymatic modification or inactivation of the drug (B)</p> Signup and view all the answers

Which of the following is a multidrug-resistant bacteria that emerged due to the increased use of vancomycin and exhibits high resistance to vancomycin?

<p>Enterococcus faecium (D)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (A)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Plasmids and transposons (A)</p> Signup and view all the answers

Which of the following is NOT a common mechanism of drug resistance?

<p>Target synthesis (B)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to multiple antimicrobials, while cross resistance confers resistance to multiple drugs via a single resistance mechanism (D)</p> Signup and view all the answers

Which of the following superbugs is responsible for causing skin infections, pneumonia, and septicemia and is resistant to all available β-lactams?

<p>Methicillin-resistant Staphylococcus aureus (MRSA) (C)</p> Signup and view all the answers

Which of the following pathogens emerged due to the increased use of vancomycin and exhibits high resistance to vancomycin?

<p>Vancomycin-resistant enterococci (VRE) (B)</p> Signup and view all the answers

Which of the following multidrug-resistant bacteria are typically members of the intestinal microbiota but can cause opportunistic infections in hospitalized patients?

<p>Extended-spectrum β-lactamase–producing gram-negative pathogens (B)</p> Signup and view all the answers

What is the difference between MDR-TB and XDR-TB?

<p>MDR-TB is resistant to all available antimicrobials, while XDR-TB is resistant to multiple antimicrobials (D)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary?

<p>To limit the spread of resistant bacteria (C)</p> Signup and view all the answers

What is necessary to combat antimicrobial resistance?

<p>Prudent antimicrobial use and new antimicrobial drug development (D)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections?

<p>All of the above (B)</p> Signup and view all the answers

What is the difference between VRSA and VISA?

<p>VRSA is resistant to vancomycin, while VISA exhibits intermediate resistance (A)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (A)</p> Signup and view all the answers

What are the two ways resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (B)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>All of the above (C)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to a single antimicrobial, while cross resistance confers resistance to multiple drugs (B)</p> Signup and view all the answers

What are the ESKAPE pathogens?

<p>Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (B)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A drug that is resistant to all available β-lactams (B)</p> Signup and view all the answers

What is the cause of the emergence of Vancomycin-resistant enterococci (VRE), vancomycin-resistant S. aureus (VRSA), and vancomycin-intermediate S. aureus (VISA)?

<p>Increased use of vancomycin (A)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota but can cause opportunistic infections in hospitalized patients (A)</p> Signup and view all the answers

What are MDR-TB and XDR-TB?

<p>Multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis (B)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary?

<p>To prevent the spread of resistant bacteria (A)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (C)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Proper use (D)</p> Signup and view all the answers

What are the two ways resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (D)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Enzymatic modification or inactivation of the drug, prevention of cellular uptake or efflux, target modification, target overproduction or enzymatic bypass, and target mimicry (C)</p> Signup and view all the answers

What are MDRs?

<p>Multidrug-resistant bacteria (C)</p> Signup and view all the answers

What are the ESKAPE pathogens?

<p>Clinically important superbugs responsible for many nosocomial infections (C)</p> Signup and view all the answers

What is MRSA?

<p>A type of skin infection (C)</p> Signup and view all the answers

What are VRE, VRSA, and VISA?

<p>Vancomycin-resistant enterococci (VRE), vancomycin-resistant S. aureus (VRSA), and vancomycin-intermediate S. aureus (VISA) (C)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota (C)</p> Signup and view all the answers

What are MDR-TB and XDR-TB?

<p>Types of tuberculosis (B)</p> Signup and view all the answers

What is the main concern with MDRs and cross resistance in clinical settings?

<p>They can lead to treatment failure and increased mortality rates (A)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary?

<p>To limit the spread of resistant bacteria (D)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>Proper use of antimicrobials and new antimicrobial drug development (D)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Patient compliance (B)</p> Signup and view all the answers

What are the two ways in which resistance can occur?

<p>Horizontal gene transfer and vertical gene transfer (A)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Prevention of cellular uptake or efflux, target modification, target overproduction or enzymatic bypass, and target mimicry (C)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to multiple antimicrobials, while cross resistance confers resistance to multiple drugs via a single resistance mechanism (C)</p> Signup and view all the answers

Which of the following is a clinically important superbug responsible for many nosocomial infections?

<p>Acinetobacter baumannii (C)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A bacterium that is resistant to all available β-lactams (B)</p> Signup and view all the answers

What is the difference between Vancomycin-resistant enterococci (VRE) and vancomycin-resistant S. aureus (VRSA)?

<p>VRE is resistant to all available β-lactams, while VRSA is resistant to vancomycin (B)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Bacteria that are typically members of the intestinal microbiota but can cause opportunistic infections in hospitalized patients (D)</p> Signup and view all the answers

What is the difference between Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>MDR-TB is resistant to a single antimicrobial, while XDR-TB is resistant to multiple antimicrobials (B)</p> Signup and view all the answers

What is the main concern with the development of rapid clinical identification methods?

<p>They may not be accurate (A)</p> Signup and view all the answers

What are the necessary steps to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (A)</p> Signup and view all the answers

Which of the following is NOT a factor that accelerates the evolution of drug resistance?

<p>Proper use (D)</p> Signup and view all the answers

What are the two ways resistance can occur?

<p>Chromosomal mutations and horizontal gene transfer (B)</p> Signup and view all the answers

What are the common mechanisms of drug resistance?

<p>Enzymatic modification or inactivation of the drug, prevention of cellular uptake or efflux, target modification, target overproduction or enzymatic bypass, and target mimicry (B)</p> Signup and view all the answers

What is the difference between multidrug-resistant microbes (MDRs) and cross resistance?

<p>MDRs are resistant to multiple antimicrobials and cross resistance confers resistance to multiple drugs via a single resistance mechanism (B)</p> Signup and view all the answers

Which of the following is NOT one of the ESKAPE pathogens?

<p>Streptococcus pneumoniae (C)</p> Signup and view all the answers

What is Methicillin-resistant Staphylococcus aureus (MRSA)?

<p>A pathogen that causes skin infections, pneumonia, and septicemia, and is resistant to all available β-lactams (A)</p> Signup and view all the answers

What are the three types of vancomycin-resistant S. aureus?

<p>VRE, VRSA, and VISA (B)</p> Signup and view all the answers

What are extended-spectrum β-lactamase–producing gram-negative pathogens and carbapenem-resistant gram-negative bacteria?

<p>Multidrug-resistant bacteria that are typically members of the intestinal microbiota but can cause opportunistic infections in hospitalized patients (B)</p> Signup and view all the answers

What is the difference between Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) and extensively drug-resistant Mycobacterium tuberculosis (XDR-TB)?

<p>MDR-TB is resistant to at least isoniazid and rifampicin, while XDR-TB is resistant to isoniazid, rifampicin, a fluoroquinolone, and at least one of three injectable second-line drugs (B)</p> Signup and view all the answers

Why is the development of rapid clinical identification methods necessary to limit the spread of resistant bacteria?

<p>To identify resistant bacteria quickly and prevent their spread in healthcare facilities (A)</p> Signup and view all the answers

What is necessary to combat antimicrobial resistance?

<p>New antimicrobial drug development and prudent antimicrobial use (C)</p> Signup and view all the answers

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