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Antimicrobial Resistance Quiz

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Questions and Answers

What is antimicrobial resistance?

Antimicrobial resistance happens when germs develop the ability to defeat drugs designed to kill them.

How does antimicrobial resistance affect the response of bacteria, viruses, fungi, and parasites to medicines?

Over time, these microorganisms no longer respond to medicines, making infections harder to treat.

What is the global public health impact of antimicrobial resistance?

Antimicrobial resistance is an urgent global public health threat, killing at least 1.27 million people worldwide in 2019.

How many antimicrobial-resistant infections occur annually in the U.S.?

More than 2.8 million antimicrobial-resistant infections occur each year in the U.S. Signup and view all the answers

Why is even resistance to one antibiotic concerning?

Resistance to even one antibiotic can lead to serious problems. Signup and view all the answers

What is the role of Clostridioides difficile in antimicrobial resistance?

Clostridioides difficile, though not typically resistant, can cause deadly diarrhea and is linked to antimicrobial use. Signup and view all the answers

What are some serious side effects of antimicrobial-resistant infections?

Organ failure Signup and view all the answers

What medical advances are dependent on the ability to fight infections using antibiotics?

Joint replacements, organ transplants, cancer therapy, and treatment of chronic diseases like diabetes, asthma, and rheumatoid arthritis Signup and view all the answers

What happens if antibiotics and antifungals lose their effectiveness?

We lose the ability to treat infections and control public health threats Signup and view all the answers

How can microbes develop resistance to specific antimicrobial agents?

By preventing access to sites, producing inactivating enzymes, possessing impermeable cell membranes, or lacking specific proteins like porins Signup and view all the answers

What are some mechanisms by which microbial cells might develop resistance to antibiotics?

Overproduction of target enzymes, altering the drug target, efflux pumping, preventing drug entry at the membrane level, having a bypass pathway, or inhibiting drug-converting enzymes Signup and view all the answers