28 Questions
What can happen as a result of overusing or unnecessarily using antibiotics?
The emergence of stronger and more resistant organisms
What impact can not finishing a course of antibiotics have?
Development of resistance to antibiotics
Which of the following is NOT a common category of antibiotics based on their chemical structures?
Steroids
Why is it important to properly classify antibiotics by their antibacterial spectrum?
To understand their effectiveness against different types of bacteria
What led to the resistance in organisms like MRSA according to the text?
Overuse or unnecessary use of antibiotics
What is the primary mechanism of action (MOA) of cephalosporins?
Inhibit bacterial cell wall synthesis
Which generation of cephalosporins has the broadest spectrum of activity against both gram-positive and gram-negative bacteria?
Fourth generation
Which generation of cephalosporins is the only one to have activity against anaerobic bacteria?
Second generation
Which of the following is a key characteristic of third generation cephalosporins?
More effective at inactivating beta-lactamase enzymes
What is the primary use of fourth generation cephalosporins?
Treatment of infections caused by multidrug-resistant bacteria
Which generation of cephalosporins is considered to have the narrowest spectrum of activity?
First generation
What is the primary purpose of antimicrobial agents?
To eliminate pathogenic microorganisms from the body
Which of the following is NOT a major class of microorganisms that can cause infections in humans?
Algae
Which of the following is a physiological barrier that helps protect the body against microbial infections?
All of the above
What is the main reason why antimicrobial agents require a prescription?
All of the above
Which of the following is NOT a common therapeutic effect of antimicrobial agents?
Boosting the immune system
What is the importance of monitoring therapeutic levels of antimicrobial agents?
All of the above
What is the main mode of action of macrolides?
Preventing protein synthesis
Which bacteria are macrolides commonly used to treat?
Streptococcus infections
What is a common side effect associated with macrolides?
Mild gastrointestinal upset
Which of the following is a contraindication for using macrolides?
Known allergy
What is the main mechanism of action of tetracyclines?
Interfering with protein synthesis
When are tetracyclines mainly used in clinical practice?
For urinary tract infections
What is the broadest antibacterial action of any antibiotics to date?
Carbapenems
What is the mechanism of action for carbapenems?
Inhibit cell wall synthesis
What is the recommended infusion time for carbapenems?
60 minutes
Which of the following is a potential adverse effect of cephalosporins?
Nephrotoxicity
What is the purpose of cilastatin when used with imipenem?
To inhibit an enzyme that breaks down imipenem
Test your knowledge on commonly used antimicrobial agents, their purpose, therapeutic and adverse effects, examples, monitoring of therapeutic levels, drug interactions, and nursing interventions. Perfect for students in PHARMACOLOGY PN 1290 class in Winter 2024.
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