6 Questions
Who were the individuals involved in the detection of weak and non-agglutinating Rh antibodies in serum?
Coombs, Mourant, and Race
What was the original name of the test now known as the direct antiglobulin test (DAT)?
Coomb’s test
In which year did Dacie present evidence of another antibody activity affecting the final reaction?
1951
Who described the principles of the AHG test in 1908?
Moreschi
What type of antibodies were detected by direct testing methods according to the text?
Only IgM antibodies
Who observed different reaction patterns with the use of dilutions of AHG testing cells with warm and cold antibodies?
Dacie
Study Notes
Detection of Rh Antibodies
- Levine and Stetson detected weak and non-agglutinating Rh antibodies in serum.
Development of the Direct Antiglobulin Test (DAT)
- The original name of the DAT was the "Coombs test".
Antibody Activity and Reaction Patterns
- In 1951, Dacie presented evidence of another antibody activity affecting the final reaction.
- Boorman and Dodd observed different reaction patterns with the use of dilutions of AHG testing cells with warm and cold antibodies.
AHG Test and Antibody Detection
- In 1908, Moreschi and Polson described the principles of the AHG test.
- Direct testing methods detected warm and cold antibodies according to the text.
Test your knowledge about the antihuman globulin test, commonly known as the Coombs test. Learn about the detection of IgM and nonagglutinating IgG antibodies, as well as the discovery of new blood group systems by Coombs, Mourant, and Race in 1945.
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