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Questions and Answers
Who were the individuals involved in the detection of weak and non-agglutinating Rh antibodies in serum?
Who were the individuals involved in the detection of weak and non-agglutinating Rh antibodies in serum?
What was the original name of the test now known as the direct antiglobulin test (DAT)?
What was the original name of the test now known as the direct antiglobulin test (DAT)?
In which year did Dacie present evidence of another antibody activity affecting the final reaction?
In which year did Dacie present evidence of another antibody activity affecting the final reaction?
Who described the principles of the AHG test in 1908?
Who described the principles of the AHG test in 1908?
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What type of antibodies were detected by direct testing methods according to the text?
What type of antibodies were detected by direct testing methods according to the text?
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Who observed different reaction patterns with the use of dilutions of AHG testing cells with warm and cold antibodies?
Who observed different reaction patterns with the use of dilutions of AHG testing cells with warm and cold antibodies?
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Study Notes
Detection of Rh Antibodies
- Levine and Stetson detected weak and non-agglutinating Rh antibodies in serum.
Development of the Direct Antiglobulin Test (DAT)
- The original name of the DAT was the "Coombs test".
Antibody Activity and Reaction Patterns
- In 1951, Dacie presented evidence of another antibody activity affecting the final reaction.
- Boorman and Dodd observed different reaction patterns with the use of dilutions of AHG testing cells with warm and cold antibodies.
AHG Test and Antibody Detection
- In 1908, Moreschi and Polson described the principles of the AHG test.
- Direct testing methods detected warm and cold antibodies according to the text.
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Description
Test your knowledge about the antihuman globulin test, commonly known as the Coombs test. Learn about the detection of IgM and nonagglutinating IgG antibodies, as well as the discovery of new blood group systems by Coombs, Mourant, and Race in 1945.
