Antihuman Globulin Test (Coombs Test)

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12 Questions

What was the original name of the test now known as the direct antiglobulin test?

Coombs' test

Who demonstrated that the antibody activity detecting Rh antibodies was associated with the anti-gamma globulin fraction in the reagent?

Coombs and Mourant

In which year did Dacie present the first evidence of another antibody activity influencing the final reaction?

1951

Which type of antibodies were detected by direct testing methods?

IgM antibodies

Who described the principles of the AHG test in 1908?

Moreschi

What did Dacie observe regarding the different reaction patterns obtained when dilutions of AHG were used to test cells sensitized with warm and cold antibodies?

Different reaction patterns

What was the original name of the test now known as the direct antiglobulin test?

Coombs-Mourant test

In what year did Coombs, Mourant, and Race detect weak and non-agglutinating Rh antibodies in serum?

1945

Who demonstrated that the antibody activity detecting Rh antibodies was associated with the anti-gamma globulin fraction in the reagent?

Dacie

What did Moreschi describe in 1908?

The principles of AHG test

Who presented the first evidence that there might be another antibody activity influencing the final reaction?

Dacie

What type of antibodies were detected by direct testing methods according to the text?

IgM antibodies only

Learn about the antihuman globulin test, also known as the Coomb's test, in this quiz by Rolly Nery Rayo, RMT. Explore the detection of IgM and IgG antibodies, as well as the discovery of new blood group systems.

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