Antihuman Globulin Test (Coombs Test)
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Questions and Answers

What was the original name of the test now known as the direct antiglobulin test?

  • DAT test
  • Coombs' test (correct)
  • Moreschi test
  • Dacie test
  • Who demonstrated that the antibody activity detecting Rh antibodies was associated with the anti-gamma globulin fraction in the reagent?

  • Dacie
  • Moreschi
  • Race
  • Coombs and Mourant (correct)
  • In which year did Dacie present the first evidence of another antibody activity influencing the final reaction?

  • 1946
  • 1908
  • 1945
  • 1951 (correct)
  • Which type of antibodies were detected by direct testing methods?

    <p>IgM antibodies</p> Signup and view all the answers

    Who described the principles of the AHG test in 1908?

    <p>Moreschi</p> Signup and view all the answers

    What did Dacie observe regarding the different reaction patterns obtained when dilutions of AHG were used to test cells sensitized with warm and cold antibodies?

    <p>Different reaction patterns</p> Signup and view all the answers

    What was the original name of the test now known as the direct antiglobulin test?

    <p>Coombs-Mourant test</p> Signup and view all the answers

    In what year did Coombs, Mourant, and Race detect weak and non-agglutinating Rh antibodies in serum?

    <p>1945</p> Signup and view all the answers

    Who demonstrated that the antibody activity detecting Rh antibodies was associated with the anti-gamma globulin fraction in the reagent?

    <p>Dacie</p> Signup and view all the answers

    What did Moreschi describe in 1908?

    <p>The principles of AHG test</p> Signup and view all the answers

    Who presented the first evidence that there might be another antibody activity influencing the final reaction?

    <p>Dacie</p> Signup and view all the answers

    What type of antibodies were detected by direct testing methods according to the text?

    <p>IgM antibodies only</p> Signup and view all the answers

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